Patents by Inventor Robert M. Pope

Robert M. Pope has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IDENTIFICATION OF CANCER BIOMARKERS AND PHOSPHORYLATED PROTEINS
    Publication number: 20120258877
    Abstract: Methods are provided for identifying proteins that are differentially expressed in disease state and normal cells. Stable isotope labeling of cells in culture allows for the identification of a multiplicity of proteins whose differential abundance in normal and disease state cells can be indicative of the disease state. Biomarkers are identified for breast cancer, in which the biomarkers are proteins having a two-fold or greater difference in abundance between breast cancer and normal cells. Identified biomarkers can be used detection methods that can provide diagnosis, typing, staging, or prognosis of cancer, such as breast cancer, or can be used to predict the response of cancer, such as breast cancer, to one or more anti-cancer agents.
    Type: Application
    Filed: February 9, 2011
    Publication date: October 11, 2012
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Robert M. POPE, Xiquan Liang, Mahbod Hajivandi, John Leite
  • COMPOSITIONS, KITS, AND METHODS FOR CALIBRATION IN MASS SPECTROMETRY
    Publication number: 20120205592
    Abstract: The invention provides compositions, kits, and methods for calibrating a mass spectrometer using two or more recombinant proteins and one or more energy-absorbing molecules. The recombinant proteins of the invention display high purities, making them suitable for use in mass spectrometry.
    Type: Application
    Filed: January 13, 2012
    Publication date: August 16, 2012
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Mahbod R. HAJIVANDI, Robert M. Pope, Mehrnoosh Sadeghi, Xiquan Liang, John Leite
  • COMPOSITIONS, KITS, AND METHODS FOR CALIBRATION IN MASS SPECTROMETRY
    Publication number: 20110226942
    Abstract: The invention provides compositions, kits, and methods for calibrating a mass spectrometer using two or more recombinant proteins and one or more energy-absorbing molecules. The recombinant proteins of the invention display high purities, making them suitable for use in mass spectrometry.
    Type: Application
    Filed: January 18, 2011
    Publication date: September 22, 2011
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: MAHBOD R. HAJIVANDI, ROBERT M. POPE, MEHRNOOSH SADEGHI, XIQUAN LIANG, JOHN F. LEITE
  • IDENTIFICATION OF CANCER BIOMARKERS AND PHOSPHORYLATED PROTEINS
    Publication number: 20090226913
    Abstract: Methods are provided for identifying proteins that are differentially expressed in disease state and normal cells. Stable isotope labeling of cells in culture allows for the identification of a multiplicity of proteins whose differential abundance in normal and disease state cells can be indicative of the disease state. Biomarkers are identified for breast cancer, in which the biomarkers are proteins having a two-fold or greater difference in abundance between breast cancer and normal cells. Identified biomarkers can be used detection methods that can provide diagnosis, typing, staging, or prognosis of cancer, such as breast cancer, or can be used to predict the response of cancer, such as breast cancer, to one or more anti-cancer agents.
    Type: Application
    Filed: December 19, 2008
    Publication date: September 10, 2009
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Robert M. Pope, Xiquan Liang, Mahbod Hajivandi, John Leite