Abstract: A composition for topical application to the skin contains as an essential component at least one of various lipids analogous to those normally found in epidermal skin, including ceramides, sphingolipids (sulfatides, sphingomyelin), phospholipids and cholesterol. In addition to these lipids, other active components act in concert to improve the skin by controlling transepidermal water loss and reversing some of the effects of the aging process. These components, which include combinations of squalane, vitamins A, C, and E, beta carotene, and various oils including evening primrose, avocado, and chamomile, are carried in a base comprised of a suitable silicone or combination thereof, the silicones in a proportion advantageously sufficient to impart a non-oily feel following application. These components act only on the epidermis, almost entirely on the stratum corneum.

Abstract: A method of treating damaged tissue by applying a composition to the damaged tissue in an amount effective to treat the damaged tissue. The composition includes a semi-occlusive ointment base and salicylic acid in an amount effective to produce keratoplasticity.