Patents by Inventor Robert M. Snapka

Robert M. Snapka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indirect labeling method for post-separation detection of chemical compounds
    Patent number: 5071775
    Abstract: A sensitive and general method of post-separation detection and quantification of chemical compounds is described. The method involves separation of unlabeled compounds by chromatography, electrophoresis or other means and selective binding of the separated compounds to ligands containing highly neutron-activatable elements, followed by neutron irradiation. The neutron-activatable elements are converted to their radiation-emitting isotopes by neutron absorption, and detection is done by autoradiography, fluorography or other means of radiation detection. The theoretical sensitivity of the method is in the attomole (10.sup.-18 mole) range.
    Type: Grant
    Filed: August 13, 1986
    Date of Patent: December 10, 1991
    Assignee: Massachusetts Institute of Technology
    Inventors: Robert M. Snapka, Kwan S. Kwok, John A. Bernard, Jr., Otto R. Harling, Alexander Varshavsky