Abstract: A method for screening, diagnosis or prognosis of sudden death in heart failure in a mammalian subject, for determining sudden death in heart failure in a mammalian subject, for identifying a mammalian subject at risk of sudden death in heart failure, or for monitoring the effect of therapy administered to a mammalian subject at experiencing imminent sudden death in heart failure included measuring the level of C-reactive protein (CRP), myeloperoxidase (MPO), neutrophil count, white blood cell count and BNP in a sample of bodily fluid from the mammalian subject. Methods for monitoring the cardiac health of a mammalian subject are further included. Kits and devices for carrying out such methods are also provided.