Patents by Inventor Robert Macke

Robert Macke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7122622
    Abstract: The invention relates to a peptide compound having an improved binding affinity to somatostatin receptors, comprising a somatostatin analogue as the peptide and a chelating group covalently linked to the N-terminal free amino group of said peptide, wherein said somatostatin analogue carries an 1-naphthylalanine or a 3-benzothienylalanine residue in its 3-position. The invention further relates to said peptide compound labeled with a detectable element or with a therapeutic radionuclide, as well as to a diagnostic method and to a method for the therapeutic treatment of tumors, by using the labeled compounds.
    Type: Grant
    Filed: April 16, 2003
    Date of Patent: October 17, 2006
    Assignee: BioSynthema Inc.
    Inventors: Helmut Robert Macke, Jean-Claude Reubi, Jörg Simon Schmitt, Mihaela Ginj
  • Publication number: 20040044177
    Abstract: The invention relates to a peptide compound having an improved binding affinity to somatostatin receptors, comprising a somatostatin analogue as the peptide and a chelating group covalently linked to the N-terminal free amino group of said peptide, wherein said somatostatin analogue carries an 1-naphthylalanine or a 3-benzothienylalanine residue in its 3-position. The invention further relates to said peptide compound labeled with a detectable element or with a therapeutic radionuclide, as well as to a diagnostic method and to a method for the therapeutic treatment of tumors, by using the labeled compounds.
    Type: Application
    Filed: April 16, 2003
    Publication date: March 4, 2004
    Inventors: Helmut Robert Macke, Jean-Claude Reubi, Jorg Simon Schmitt, Mihaela Ginj
  • Patent number: 5511574
    Abstract: A thrust block for an irrigation system enables a high pressure valve or other component connected to the thrust block to be easily replaced without digging out a concrete block and surrounding portion of the ground and sectioning the adjacent pipe sections. The valve includes flanges on each end thereof which are releasably secured to similarly configured flanges on couplings. Braces are partially embedded within a concrete block beneath the valve and an upper end of each brace is secured to the fasteners joining the conventional flanges of the valve and the coupling. A push-on fitting is provided on each coupling for easy assembly of the coupling to the adjacent pipe sections.
    Type: Grant
    Filed: November 15, 1994
    Date of Patent: April 30, 1996
    Inventor: Robert Macke