Patents by Inventor Robert MAKA

Robert MAKA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CD25-biased anti-IL-2 antibody
    Patent number: 12692306
    Abstract: The invention provides a human IL-2 (hIL-2)-specific monoclonal antibody, wherein a complex of hIL-2 and the monoclonal induces IL-2 signalling preferentially via CD25 and the trimeric IL-2R. The invention further provides a pharmaceutical composition comprising hIL-2 and said hIL-2-mAb for use treating inflammatory disease.
    Type: Grant
    Filed: August 18, 2021
    Date of Patent: July 28, 2026
    Assignee: UNIVERSITÄT ZÜRICH
    Inventors: Onur Boyman, Ufuk Karakus, Miro Raeber, Roman Meledin, Robert Maka
  • A CD25-BIASED ANTI-IL-2 ANTIBODY
    Publication number: 20230303680
    Abstract: The invention provides a human IL-2 (hlL-2)-specific monoclonal antibody, wherein a complex of hlL-2 and the monoclonal induces IL-2 signalling preferentially via CD25 and the trimeric IL-2R. The invention further provides a pharmaceutical composition comprising hlL-2 and said hlL-2-mAb for use treating inflammatory disease.
    Type: Application
    Filed: August 18, 2021
    Publication date: September 28, 2023
    Applicant: UNIVERSITÄT ZÜRICH
    Inventors: Onur BOYMAN, Ufuk KARAKUS, Miro RAEBER, Roman MELEDIN, Robert MAKA