Patents by Inventor Robert Malmstrom

Robert Malmstrom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS
    Publication number: 20250332156
    Abstract: Disclosed are compounds of Formula (I) or pharmaceutically acceptable salts or solvates thereof, wherein R1, R2, R2a, R3, R3a, m, n, and W are as defined herein. The compounds are, for example, inhibitors of WRN helicase and useful in treating a proliferative disease, such as cancer.
    Type: Application
    Filed: July 5, 2023
    Publication date: October 30, 2025
    Inventors: Shota Kikuchi, Betty Lam, Jason Green, Don Rogness, David Weinstein, Larry Burgess, Robert Malmstrom
  • PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS
    Publication number: 20250188040
    Abstract: Disclosed are compounds of Formula (I): or pharmaceutically acceptable salts or solvates thereof, wherein R1, R3, X, Y, Z, and W are as defined herein. The compounds are, for example, inhibitors of WRN helicase and useful in treating a proliferative disease, such as cancer.
    Type: Application
    Filed: December 10, 2024
    Publication date: June 12, 2025
    Inventors: Shota Kikuchi, Betty Lam, Jason Green, Don Rogness, David Weinstein, Larry Burgress, Benjamin Homing, Kelsey Lamb, Zachary Owyang, Robert Malmstrom
  • COMPOUNDS AND METHODS FOR MODULATING STAT3
    Publication number: 20250059161
    Abstract: Compounds and methods for inhibiting STAT3.
    Type: Application
    Filed: March 1, 2024
    Publication date: February 20, 2025
    Inventors: Qingfeng WU, Brian COOK, Michael WALLACE, Jonathan POLLACK, Aaron SNEAD, Bryan LEE, Robert MALMSTROM, Gabriel HAMMERSLEY, Mariangela URBANO, Jason GREEN, Philip ALABI
  • Pharmaceutical compositions comprising WRN helicase inhibitors
    Patent number: 12187685
    Abstract: Disclosed are compounds of Formula (I): or pharmaceutically acceptable salts or solvates thereof, wherein R1, R3, X, Y, Z, and W are as defined herein. The compounds are, for example, inhibitors of WRN helicase and useful in treating a proliferative disease, such as cancer.
    Type: Grant
    Filed: September 20, 2023
    Date of Patent: January 7, 2025
    Inventors: Shota Kikuchi, Betty Lam, Jason Green, Don Rogness, David Weinstein, Larry Burgess, Benjamin Horning, Kelsey Lamb, Zachary Owyang, Robert Malmstrom
  • PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS
    Publication number: 20240140915
    Abstract: Disclosed are compounds of Formula (I): or pharmaceutically acceptable salts or solvates thereof, wherein R1, R3, X, Y, Z, and W are as defined herein. The compounds are, for example, inhibitors of WRN helicase and useful in treating a proliferative disease, such as cancer.
    Type: Application
    Filed: September 20, 2023
    Publication date: May 2, 2024
    Inventors: Shota Kikuchi, Betty Lam, Jason Green, Don Rogness, David Weinstein, Larry Burgess, Benjamin Horning, Kelsey Lamb, Zachary Owyang, Robert Malmstrom
  • PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS
    Publication number: 20240067612
    Abstract: Disclosed are compounds of Formula (I): or pharmaceutically acceptable salts or solvates thereof, wherein R1, R3, X, Y, Z, and W are as defined herein. The compounds are, for example, inhibitors of WRN helicase and useful in treating a proliferative disease, such as cancer.
    Type: Application
    Filed: July 5, 2023
    Publication date: February 29, 2024
    Inventors: Shota Kikuchi, Betty Lam, Jason Green, Don Rogness, David Weinstein, Larry Burgess, Benjamin Horning, Kelsey Lamb, Zach Owyang, Robert Malmstrom
  • PI3KGAMMA inhibitors
    Patent number: 11344559
    Abstract: The present disclosure relates to PI3K? inhibitors and methods of their use.
    Type: Grant
    Filed: June 25, 2020
    Date of Patent: May 31, 2022
    Assignee: The Regents of the University of California
    Inventors: Judith Varner, Rommie Amaro, Megan Kaneda, Robert Malmstrom, Victoria Feher
  • PI3KGAMMA INHIBITORS
    Publication number: 20200405730
    Abstract: The present disclosure relates to PI3K? inhibitors and methods of their use.
    Type: Application
    Filed: June 25, 2020
    Publication date: December 31, 2020
    Inventors: Judith Varner, Rommie Amaro, Megan Kaneda, Robert Malmstrom, Victoria Feher