Patents by Inventor Robert Mark Worden
Robert Mark Worden has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10246786Abstract: An inexpensive, easily renewable bioelectronic device useful for bioreactors, biosensors, and biofuel cells includes an electrically conductive carbon electrode and a bioelectronic interface bonded to a surface of the electrically conductive carbon electrode, wherein the bioelectronic interface includes catalytically active material that is electrostatically bound directly or indirectly to the electrically conductive carbon electrode to facilitate easy removal upon a change in pH, thereby allowing easy regeneration of the bioelectronic interface.Type: GrantFiled: June 9, 2016Date of Patent: April 2, 2019Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITYInventors: Robert Mark Worden, Brian L. Hassler, Lawrence T. Drzal, IIsoon Lee
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Patent number: 9714404Abstract: Various embodiments provide a bioreactor for producing a bioproduct comprising one or more catalytically active zones located in a housing and adapted to keep two incompatible gaseous reactants separated when in a gas phase, wherein each of the one or more catalytically active zones may comprise a catalytic component retainer and a catalytic component retained within and/or thereon. Each of the catalytically active zones may additionally or alternatively comprise a liquid medium located on either side of the catalytic component retainer. Catalytic component may include a microbial cell culture located within and/or on the catalytic component retainer, a suspended catalytic component suspended in the liquid medium, or a combination thereof. Methods of using various embodiments of the bioreactor to produce a bioproduct, such as isobutanol, are also provided.Type: GrantFiled: March 6, 2014Date of Patent: July 25, 2017Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITYInventors: Robert Mark Worden, Yangmu Chloe Liu
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Patent number: 9601227Abstract: Electrically conductive nanowires, and genetically or chemically modified production and use of such nanowires with altered conductive, adhesive, coupling or other properties are described. The disclosed nanowires are used as device or device components or may be adapted for soluble metal remediation.Type: GrantFiled: February 28, 2014Date of Patent: March 21, 2017Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITYInventors: Gemma Reguera, Dena Cologgi, Robert Mark Worden, Angelines A. Castro-Forero, Rebecca Steidl
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Publication number: 20160326658Abstract: An inexpensive, easily renewable bioelectronic device useful for bioreactors, biosensors, and biofuel cells includes an electrically conductive carbon electrode and a bioelectronic interface bonded to a surface of the electrically conductive carbon electrode, wherein the bioelectronic interface includes catalytically active material that is electrostatically bound directly or indirectly to the electrically conductive carbon electrode to facilitate easy removal upon a change in pH, thereby allowing easy regeneration of the bioelectronic interface.Type: ApplicationFiled: June 9, 2016Publication date: November 10, 2016Inventors: Robert Mark Worden, Brian L. Hassler, Lawrence T. Drzal, IIsoon Lee
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Patent number: 9406959Abstract: An inexpensive, easily renewable bioelectronic device useful for bioreactors, biosensors, and biofuel cells includes an electrically conductive carbon electrode and a bioelectronic interface bonded to a surface of the electrically conductive carbon electrode, wherein the bioelectronic interface includes catalytically active material that is electrostatically bound directly or indirectly to the electrically conductive carbon electrode to facilitate easy removal upon a change in pH, thereby allowing easy regeneration of the bioelectronic interface.Type: GrantFiled: April 23, 2010Date of Patent: August 2, 2016Assignee: Board of Trustees of Michigan State UniversityInventors: Robert Mark Worden, Brian L Hassler, Lawrence T. Drzal, Ilsoon Lee
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Publication number: 20140239237Abstract: Electrically conductive nanowires, and genetically or chemically modified production and use of such nanowires with altered conductive, adhesive, coupling or other properties are described. The disclosed nanowires are used as device or device components or may be adapted for soluble metal remediation.Type: ApplicationFiled: February 28, 2014Publication date: August 28, 2014Applicant: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITYInventors: Gemma REGUERA, Dena COLOGGI, Robert Mark WORDEN, Angelines A. CASTRO-FORERO, Rebecca STEIDL
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Publication number: 20140187826Abstract: Various embodiments provide a bioreactor for producing a bioproduct comprising a housing; and one or more catalytically active zones located in the housing and adapted to keep two incompatible gaseous reactants separated when in a gas phase, wherein each of said catalytically active zone comprises a catalytic component retainer and a catalytic component retained within and/or on the catalytic component retainer. Each of said catalytically active zones may additionally or alternatively comprise a liquid medium located on either side of the catalytic component retainer and the catalytic component may additionally or alternatively be a suspended catalytic component suspended in a liquid medium located on either side of the catalytic component retainer. Methods of using various embodiments of the bioreactor to produce a bioproduct, such as isobutanol, are also provided.Type: ApplicationFiled: March 6, 2014Publication date: July 3, 2014Applicant: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITYInventors: Robert Mark WORDEN, Yangmu Chloe LIU
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Patent number: 6326203Abstract: A method and bioreactor (10) apparatus is described for maintaining cells in a culture medium containing gas or liquid aphrons. A preferred microbubble generator (42, 42A) of a gas which is necessary for maintaining the cells to produce plant described chemicals is described. Bioparticles (11) containing magnetically susceptible particles are provided in a column (12) surrounded by solenoids (13, 14, 14A) which act to hold the bioparticles in position in the column. Preferably, one of the solenoids with a magnetically susceptible screen (24) acts as a valve to allow a portion of the bioparticles to be removed from the column.Type: GrantFiled: December 14, 1999Date of Patent: December 4, 2001Assignee: Board of Trustees operating Michigan State UniversityInventors: Robert Mark Worden, Tyler T. Ames
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Patent number: 6087158Abstract: A method and bioreactor (10) apparatus is described for maintaining cells in a culture medium containing gas or liquid aphrons. A preferred microbubble generator (42, 42A) of a gas which is necessary for maintaining the cells to produce plant derived chemicals is described. Bioparticles (11) containing magnetically susceptible particles are provided in a column (12) surrounded by a solenoids (13, 14, 14A) which act to hold the bioparticles in position in the column. Preferably, one of the solenoids with a magnetically susceptible screen (24) acts as a valve to allow a portion of the bioparticles to be removed from the column.Type: GrantFiled: April 27, 1999Date of Patent: July 11, 2000Assignee: Board of Trustees Operating Michigan State UniversityInventors: Robert Mark Worden, Tyler T. Ames
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Patent number: 6054319Abstract: A method and bioreactor (10) apparatus is described for maintaining cells in a culture medium containing gas or liquid aphrons. A preferred microbubble generator (42, 42A) of a gas which is necessary for maintaining the cells to produce plant derived chemicals is described. Bioparticles (11) containing magnetically susceptible particles are provided in a column (12) surrounded by a solenoids (13, 14, 14A) which act to hold the bioparticles in position in the column. Preferably, one of the solenoids with a magnetically susceptible screen (24) acts as a valve to allow a portion of the bioparticles to be removed from the column.Type: GrantFiled: February 3, 1998Date of Patent: April 25, 2000Assignee: Board of Trustees operating Michigan State UniversityInventors: Robert Mark Worden, Tyler T. Ames
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Patent number: 6022727Abstract: A method for forming gas or liquid aphrons with reversible surfactants or emulsifiers is described. Polymers which change their emulsifying properties upon change of pH, temperature or other condition are used to form the aphrons. The aphrons are useful for chemical reactions and separations, mass transfer processes, and for biological processes.Type: GrantFiled: January 12, 1998Date of Patent: February 8, 2000Assignee: Board of Trustees Operating Michigan State UniversityInventors: Robert Mark Worden, Alec B. Scranton
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Patent number: 5885826Abstract: A method and bioreactor apparatus is described for growing plant cells, particularly to produce plant derived chemicals is described. Bioparticles (11) containing magnetically susceptible particles are provided in a column (12) surrounded by a solenoids (13, 14, 14A) which act to hold the bioparticles in position in the column. One of the solenoids with a magnetically susceptible screen (24) acts as a valve to allow a portion of the bioparticles to be removed from the column. The method is particularly described for producing daidzein and genistein.Type: GrantFiled: December 22, 1997Date of Patent: March 23, 1999Assignee: Board of Trustees operating Michigan State UniversityInventors: Robert Mark Worden, Kenneth C. Sink, Tyler T. Ames, Vicki S. Thompson
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Patent number: 5846829Abstract: A method and bioreactor (10) apparatus is described for growing plant cells, particularly to produce plant derived chemicals is described. Bioparticles (11) containing magnetically susceptible particles are provided in a column (12) surrounded by a solenoids (13, 14, 14A) which act to hold the bioparticles in position in the column. One of the solenoids with a magnetically susceptible screen (24) acts as a valve to allow a portion of the bioparticles to be removed from the column. The method is particularly described for producing daidzein and genistein.Type: GrantFiled: November 8, 1996Date of Patent: December 8, 1998Assignee: Board of Trustees operating Michigan State UniversityInventors: Robert Mark Worden, Kenneth C. Sink, Tyler T. Ames, Vicki S. Thompson