Patents by Inventor Robert Martienssen

Robert Martienssen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230235348
    Abstract: The present disclosure provides methods for increasing meiotic recombination in crop plants, as well as plants and seeds produced by such methods.
    Type: Application
    Filed: July 19, 2022
    Publication date: July 27, 2023
    Applicants: Cold Spring Harbor Laboratory, Cambridge Enterprise Limited
    Inventors: Robert Martienssen, Charles Underwood, Ian Henderson
  • Patent number: 8273528
    Abstract: Methods and compositions for determining the methylation profile of individuals and using the profiles to identify clones with desired traits.
    Type: Grant
    Filed: January 16, 2007
    Date of Patent: September 25, 2012
    Assignees: Cold Spring Harbor Laboratory, Washington University
    Inventors: Robert Martienssen, Eric J. Richards, Zachary Lippmann, Vincent Colot
  • Publication number: 20070178506
    Abstract: Methods and compositions for determining the methylation profile of individuals and using the profiles to identify clones with desired traits.
    Type: Application
    Filed: January 16, 2007
    Publication date: August 2, 2007
    Applicant: Cold Spring Harbor Laboratory and Washington University
    Inventors: Robert Martienssen, Eric Richards, Zachary Lippmann, Vincent Colot
  • Patent number: 7186512
    Abstract: Methods and compositions for determining the methylation profile of individuals and using the profiles to identify clones with desired traits.
    Type: Grant
    Filed: June 26, 2003
    Date of Patent: March 6, 2007
    Assignees: Cold Spring Harbor Laboratory, Washington University
    Inventors: Robert Martienssen, Eric J. Richards, Zachary Lippmann, Vincent Colot
  • Publication number: 20050112763
    Abstract: Methods of regulating the formation of heterochromatin at a target locus within the genome of a cell and methods of regulating the modification of a histone protein assumed on the DNA of a target locus within the genome of a cell are provided. In particular, the invention provides methods to regulate the structure of the genome of a cell, where the structure is regulated by modulating heterochromatin formation, heterochromatin architecture, histone methylation, and/or DNA methylation, by exposing the cell to an RNAi probe complementary to a target locus so as to activate the RNAi machinery to modify the genomic structure of the target locus and adjacent segments of the genome.
    Type: Application
    Filed: August 20, 2004
    Publication date: May 26, 2005
    Inventors: Shivinder Grewal, Thomas Volpe, Ira Hall, Catherine Kidner, Robert Martienssen
  • Publication number: 20040132048
    Abstract: Methods and compositions for determining the methylation profile of individuals and using the profiles to identify clones with desired traits.
    Type: Application
    Filed: June 26, 2003
    Publication date: July 8, 2004
    Inventors: Robert Martienssen, Eric J. Richards, Zachary Lippmann, Vincent Colot
  • Publication number: 20040058375
    Abstract: This invention provides methods by which repetitive elements can be selectively removed from genomic libraries made from complex eukaryotic genomes. In particular, the invention relates to affecting the efficiency of recovery of novel genes and regulatory sequences, by use of methylation restrictive bacteria, cell-free enzymes, and methyl-binding proteins.
    Type: Application
    Filed: September 5, 2003
    Publication date: March 25, 2004
    Applicant: Cold Spring Harbor Laboratory
    Inventors: W. Richard McCombie, Robert A. Martienssen
  • Publication number: 20030180775
    Abstract: This invention provides methods by which repetitive elements can be selectively removed from genomic libraries made from complex eukaryotic genomes. In particular, the invention relates to affecting the efficiency of recovery of novel genes and regulatory sequences, by use of methylation restrictive bacteria, cell-free enzymes, and methyl-binding proteins.
    Type: Application
    Filed: February 20, 2003
    Publication date: September 25, 2003
    Applicant: Cold Spring Harbor Laboratory
    Inventors: W. Richard McCombie, Robert A. Martienssen
  • Publication number: 20030157546
    Abstract: This invention provides methods by which repetitive elements can be selectively removed from genomic libraries made from complex eukaryotic genomes. In particular, the invention relates to affecting the efficiency of recovery of novel genes and regulatory sequences, by use of methylation restrictive bacteria, cell-free enzymes, and methyl-binding proteins.
    Type: Application
    Filed: February 20, 2003
    Publication date: August 21, 2003
    Applicant: Cold Spring Harbor Laboratory
    Inventors: W. Richard McCombie, Robert A. Martienssen
  • Patent number: 6541683
    Abstract: The present invention provides a non-naturally occurring seed plant that is characterized by producing seeds of increased size due to ectopic expression of a nucleic acid molecule encoding an AGL8-related gene product. The AGL8-related gene product can have, for example, substantially the amino acid sequence of an AGL8 ortholog such as Arabidopsis AGL8 (SEQ ID NO:2). The present invention further provides a non-naturally occurring seed plant that is characterized by producing fruit of increased size due to ectopic expression of a nucleic acid molecule encoding an AGL8-family gene product. The AGL8-family gene product can have substantially the amino acid sequence of an AGL8 ortholog, for example, the amino acid sequence of Arabidopsis AGL8 (SEQ ID NO:2). Related methods and kits also are provided.
    Type: Grant
    Filed: November 7, 2000
    Date of Patent: April 1, 2003
    Assignees: The Regents of the University of California, Cold Spring Harbor Laboratory
    Inventors: Martin F. Yanofsky, Robert Martienssen, Cristina Ferrandiz, Qing Gu
  • Publication number: 20010046669
    Abstract: This invention provides methods by which repetitive elements can be selectively removed from genomic libraries made from complex eukaryotic genomes. In particular, the invention relates to affecting the efficiency of recovery of novel genes and regulatory sequences, by use of methylation restrictive hosts.
    Type: Application
    Filed: October 29, 1999
    Publication date: November 29, 2001
    Inventors: William R. McCobmie, Pablo D. Rabinowicz, Robert A. Martienssen
  • Patent number: 6229068
    Abstract: The present invention provides a non-naturally occurring seed plant that is characterized by producing seeds of increased size due to ectopic expression of a nucleic acid molecule encoding an AGL8-related gene product. The AGL8-related gene product can have, for example, substantially the amino acid sequence of an AGL8 ortholog such as Arabidopsis AGL8 (SEQ ID NO:2). The present invention further provides a non-naturally occurring seed plant that is characterized by producing fruit of increased size due to ectopic expression of a nucleic acid molecule encoding an AGL8-family gene product. The AGL8-family gene product can have substantially the amino acid sequence of an AGL8 ortholog, for example, the amino acid sequence of Arabidopsis AGL8 (SEQ ID NO:2). Related methods and kits also are provided.
    Type: Grant
    Filed: June 26, 1998
    Date of Patent: May 8, 2001
    Assignees: Cold Spring Harbor Labs.,, The Regents of the University of California
    Inventors: Martin F. Yanofsky, Robert Martienssen, Cristina Ferrandiz, Qing Gu