Abstract: The present disclosure describes, in part, compositions and methods for the treatment of NASH and NASH-associated diseases. Compositions comprising an agent able to increases the expression, activity, or level of one more of a protective miRNA, preferably miR-375 are provided that may be used for the treatment of liver and/or liver-associated disease is treated in the subject.

Abstract: A bulk syrup delivery system in which a compartmentized tank delivery truck includes a plurality of separate compartments or tanks, generally one for each of several different types of soft drink syrup. One multichannel delivery hose, having one channel or passageway for each type of syrup, extends from a hose reel on the delivery truck to a delivery receptacle at the account. The account has a plurality of separate storage tanks, each of which is coupled to the delivery receptacle, which is designed to couple to the end of the delivery hose, such that each compartment in the delivery truck couples to the proper storage tank in the account. A plurality of separate check or closure valves are installed in each side of the coupling between the hose and the delivery receptacle, such that flow therebetween is prevented until the valves are opened. The compartments in the delivery truck are pressurized (e.g.