Abstract: Described herein are methods that define cellular populations that are sensitive to RARA agonists and identify patient populations that will benefit from treatment with RARA agonists. The methods may comprise administering RARA agonists to patient populations.

Abstract: The invention provides methods that define cellular populations that are sensitive to RARA agonists and identify patient subgroups that will benefit from treatment with RARA agonists. The invention also provides packaged pharmaceutical compositions that comprise a RARA agonist and instructions for determining if such agonist is suitable for use in treatment.

Abstract: The invention provides methods that define cellular populations that are sensitive to RARA agonists and identify patient subgroups that will benefit from treatment with RARA agonists. The invention also provides packaged pharmaceutical compositions that comprise a RARA agonist and instructions for determining if such agonist is suitable for use in treatment.

Abstract: A shape card for self-assessment of a shape of a hair includes a first part, a second part, and a third part. The first part includes one or more first reference markers for assessing a number of hair waves. The second part includes one or more second reference markers for assessing hair curvature. The third part includes one or more descriptors each describing a target hair shape. The target hair shape is a result of a combination of one of the one or more first reference markers and one of the one or more second reference markers.

Abstract: Described herein are methods that define cellular populations that are sensitive to RARA agonists and identify patient populations that will benefit from treatment with RARA agonists. The methods may comprise administering RARA agonists to patient populations.

Abstract: Described herein are methods that define cellular populations that are sensitive to RARA agonists and identify patient populations that will benefit from treatment with RARA agonists. The methods may comprise administering RARA agonists to patient populations.

Abstract: A method of measuring indications of hair type of a user, the method comprising the steps of: providing a mobile device; providing a reference card, the reference card including one or more reference markers; providing one or more of the user's hairs at the 5 surface of the reference card; acquiring one or more images of said one or more hairs using the mobile device; identifying the path of each of the one or more hairs along the reference card; and calculating the curve of each hair from its identified path.

Abstract: The invention provides methods that define cellular populations that are sensitive to RARA agonists and identify patient subgroups that will benefit from treatment with RARA agonists. The invention also provides packaged pharmaceutical compositions that comprise a RARA agonist and instructions for determining if such agonist is suitable for use in treatment.

Abstract: A method of measuring indications of hair type of a user, the method comprising the steps of: providing a mobile device; providing a reference card, the reference card including one or more reference markers; providing one or more of the user's hairs at the surface of the reference card; acquiring one or more images of said one or more hairs using the mobile device; identifying the path of each of the one or more hairs along the reference card; and calculating the diameter of each hair from the acquired image.

Abstract: A method of analysing at least one hair surface using a 3D printer includes collecting a first imaging data for the at least one hair surface; applying at least one treatment to the at least one hair surface, the at least one treatment including at least one benefit agent; collecting a second imaging data for the at least one hair surface after applying the at least one treatment; converting the first imaging data into a first formatted data, the first formatted data associated with the 3D printer; converting the second imaging data into a second formatted data, the second formatted data associated with the 3D printer; producing a first 3D model of the at least one hair surface from the 3D printer using the first formatted data; and producing a second 3D model of the at least one hair surface from the 3D printer using the second formatted data.

Abstract: A method of analysing at least one hair surface using a 3D printer includes collecting a first imaging data for the at least one hair surface; applying at least one assault to the at least one hair surface; collecting a second imaging data for the at least one hair surface after applying the at least one assault; converting the first imaging data into a first formatted data, the first formatted data associated with the 3D printer; converting the second imaging data into a second formatted data, the second formatted data associated with the 3D printer; producing a first 3D model of the at least one hair surface from the 3D printer using the first formatted data; and producing a second 3D model of the at least one hair surface from the 3D printer using the second formatted data.

Abstract: Described herein are methods that define cellular populations that are sensitive to RARA agonists and identify patient populations that will benefit from treatment with RARA agonists. The methods may comprise administering RARA agonists to patient populations.

Abstract: Described herein are methods that define cellular populations that are sensitive to RARA agonists and identify patient populations that will benefit from treatment with RARA agonists. The methods may comprise administering RARA agonists to patient populations.

Abstract: A method of analysing the effect of an assault on hair, comprising the steps of: (i) collecting imaging data for at least one hair surface, (ii) applying at least one assault to the at least one hair surface, (iii) collecting imaging data for the at least one hair surface arising from step (ii), (iv) converting the imaging data collected at steps (i) and (iii) into a format to create magnified images from a 3D printer, (v) producing magnified 3D models of the at least one hair surface from a 3D printer using the data from step (iv), (vi) comparing the 3D model arising from step (iii) to the 3D model of step (i) and (vii) assessing the degree of damage to the hair.

Abstract: A method of analysing the effect and deposition of remedial and beneficial treatments on hair, comprising the steps of: (i) collecting imaging data for at least one hair surface, (ii) applying at least one treatment, comprising at least one benefit agent, to the hair surface, to deposit the benefit agent onto the hair surface, (iii) collecting imaging data for the hair surface arising from step (ii), (iv) converting the imaging data collected at steps (i) and (iii) into a format to create magnified images from a 3D printer, 10 (v) producing magnified 3D models of the hair surface from a 3D printer using the data from step iv, (vi) comparing the 3D model arising from step (iii) to the 3D model arising from step (i), (vii) analyzing the deposition behavior of the benefit agent, (viii) analyzing any consumer perceivable effect resulting from step (ii), and (ix) correlating the analysis of step (vii) to the analysis of step (viii).

Abstract: A method of measuring indications of hair type of a user, the method comprising the steps of: providing a mobile device; providing a reference card, the reference card including one or more reference markers; providing one or more of the user's hairs at the surface of the reference card; acquiring one or more images of said one or more hairs using the mobile device; identifying the path of each of the one or more hairs along the reference card; and calculating the diameter of each hair from the acquired image.

Abstract: A method of measuring indications of hair type of a user, the method comprising the steps of: providing a mobile device; providing a reference card, the reference card including one or more reference markers; providing one or more of the user's hairs at the 5 surface of the reference card; acquiring one or more images of said one or more hairs using the mobile device; identifying the path of each of the one or more hairs along the reference card; and calculating the curve of each hair from its identified path.

Abstract: Described herein are methods that define cellular populations that are sensitive to RARA agonists and identify patient populations that will benefit from treatment with RARA agonists. The methods may comprise administering RARA agonists to patient populations.

Abstract: Described herein are methods that define cellular populations that are sensitive to RARA agonists and identify patient populations that will benefit from treatment with RARA agonists. The methods may comprise administering RARA agonists to patient populations.

Abstract: Described herein are methods that define cellular populations that are sensitive to RARA agonists and identify patient populations that will benefit from treatment with RARA agonists. The methods may comprise administering RARA agonists to patient populations.