Abstract: An NMR apparatus having a magnet coil system for generating a homogeneous magnetic field comprises a superconducting magnet arranged within a vacuum vessel in the cold region of a cryostat, and a shim system containing shim elements arranged outside the vacuum vessel. The superconducting magnet has a first mechanical connection point to the vacuum vessel via a magnet suspension, and the shim system has a second mechanical connection point to the vacuum vessel via a positioning element. On at least one portion of a path along the vacuum vessel from the first connection point to the second connection point and/or on at least one portion of a path along the positioning element from the second connection point to the shim system, a regulating element for regulating thermally caused changes in length is arranged on the relevant path. Magnetic field homogeneity can thus be kept largely stable.

Abstract: Provided are crystalline forms of a KRAS G12C inhibitor compound and to processes for their preparation. Furthermore, provided is pharmaceutical composition comprising said crystalline forms, and at least one pharmaceutically acceptable excipient. The pharmaceutical composition can be used as a medicament, in particular for the treatment of cancer, and KRAS G12C-mutant cancer.

Abstract: The present disclosure provides methods of producing a plant that exhibits an enhanced trait selected from the group consisting of altered hexose sugar level, altered starch level, altered sucrose phosphate synthase activity, altered ureide level and delayed senescence, as compared to a control plant. The present disclosure also provides transgenic cells, plants, plant parts, seeds, progeny plants, products or commodity products produced by this method.

Abstract: Polynucleotides and polypeptides incorporated into expression vectors have been introduced into plants and were ectopically expressed. The polypeptides of the invention have been shown to confer at least one regulatory activity and confer increased yield, greater height, greater early season growth, greater canopy coverage, greater stem diameter, greater late season vigor, increased secondary rooting, more rapid germination, greater cold tolerance, greater tolerance to water deprivation, reduced stomatal conductance, altered C/N sensing, increased low nitrogen tolerance, increased low phosphorus tolerance, or increased tolerance to hyperosmotic stress as compared to the control plant as compared to a control plant.

Abstract: Polynucleotides and polypeptides incorporated into expression vectors have been introduced into plants and were ectopically expressed. The polypeptides of the invention have been shown to confer at least one regulatory activity and confer increased yield, greater height, greater early season growth, greater canopy coverage, greater stem diameter, greater late season vigor, increased secondary rooting, more rapid germination, greater cold tolerance, greater tolerance to water deprivation, reduced stomatal conductance, altered C/N sensing, increased low nitrogen tolerance, increased low phosphorus tolerance, or increased tolerance to hyperosmotic stress as compared to the control plant as compared to a control plant.

Abstract: This invention provides molecular constructs and methods for the temporally specific control of gene expression in plants or in plant pests or pathogens. More specifically, this invention provides plant miRNA genes having novel circadian expression patterns that are useful for designing recombinant DNA constructs for temporally specific expression of at least one gene. Also provided are non-natural transgenic plant cells, plants, and seeds containing in their genome a recombinant DNA construct of this invention.

Abstract: Methods and compositions for modulating plant development are provided. Methods employing type A Response Regulators (RR) are provided. The type A RR sequences are used in a variety of methods including modulating root development, modulating leaf and/or shoot development, modulating shoot regeneration from callus, modulating tolerance under abiotic stress, modulating yield, modulating cytokinin level/activity, and modulating plant responsiveness to cytokinin. Transformed plants, plant cell, tissues, seed, and expression vectors are also provided.

Abstract: Isolated polynucleotides that encode cytokinin-sensing histidine kinase polypeptides, and the encoded polypeptides, are described. Expression cassettes comprising the polynucleotides of the invention and plants and plant cells that are transformed with the polynucleotides are described. Methods of using the cytokinin-sensing histidine kinase polypeptides and polynucleotides to modulate histidine kinase activity and/or histidine kinase levels in plants and plant cells are further described.

Abstract: A sensor for measuring stress, temperature, pressure, sound, etc. comprising an optical waveguide, preferably an optical fiber waveguide, a light source which injects light into one end of the waveguide, a deformer contacting and deforming the waveguide to cause light to couple from originally excited modes to other modes, and an optical detector to detect the change in light coupling caused by deformation of the waveguide.

Abstract: A sensor for measuring stress, temperature, pressure, sound, etc. comprising an optical waveguide, preferably an optical fiber waveguide, a light source which injects light into one end of the waveguide, a deformer contacting and deforming the waveguide to cause light to couple from originally excited modes to other modes, and an optical detector to detect the change in light coupling caused by deformation of the waveguide.