Patents by Inventor Robert Michael Strongin

Robert Michael Strongin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Analyte detection using near-infrared fluorophores
    Patent number: 10197574
    Abstract: Embodiments of compounds for selectively detecting an analyte are disclosed, along with methods and kits for detecting analytes with the compounds. The compounds are bridged viologen conjugates including at least one fluorophore according to the general structure At least one of R1/R2, R2/R3, R3/R4, R5/R6, R6/R7, and/or R7/R8 together form a substituted or unsubstituted cycloalkyl or aryl.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: February 5, 2019
    Assignee: Portland State University
    Inventors: Robert Michael Strongin, Martha Sibrian-Vazquez, Jorge Omar Escobedo-Cordova, Mark Allen Lowry
  • Near-infrared fluorescent dyes with large stokes shifts
    Patent number: 9958451
    Abstract: Embodiments of near-infrared (NIR) dyes are disclosed, along with methods and kits for detecting analytes with the NIR dyes. The NIR dyes have a structure according to the general structure At least one of R1/R2, R2/R3, R3/R4, R5/R6, R6/R7, and/or R7/R8 together forms a substituted or unsubstituted cycloalkyl or aryl.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: May 1, 2018
    Assignee: Portland State University
    Inventors: Robert Michael Strongin, Martha Sibrian-Vazquez, Jorge Omar Escobedo-Cordova, Mark Allen Lowry
  • ANALYTE DETECTION USING NEAR-INFRARED FLUOROPHORES
    Publication number: 20160223558
    Abstract: Embodiments of compounds for selectively detecting an analyte are disclosed, along with methods and kits for detecting analytes with the compounds. The compounds are bridged viologen conjugates including at least one fluorophore according to the general structure At least one of R1/R2, R2/R3, R3/R4, R5/R6, R6/R7, and/or R7/R8 together form a substituted or unsubstituted cycloalkyl or aryl.
    Type: Application
    Filed: January 28, 2016
    Publication date: August 4, 2016
    Applicant: Portland State University
    Inventors: Robert Michael Strongin, Martha Sibrian-Vazquez, Jorge Omar Escobedo-Cordova, Mark Allen Lowry
  • NEAR-INFRARED FLUORESCENT DYES WITH LARGE STOKES SHIFTS
    Publication number: 20160154001
    Abstract: Embodiments of near-infrared (NIR) dyes are disclosed, along with methods and kits for detecting analytes with the NIR dyes. The NIR dyes have a structure according to the general structure At least one of R1/R2, R2/R3, R3/R4, R5/R6, R6/R7, and/or R7/R8 together forms a substituted or unsubstituted cycloalkyl or aryl.
    Type: Application
    Filed: December 15, 2015
    Publication date: June 2, 2016
    Applicant: Portland State University
    Inventors: Robert Michael Strongin, Martha Sibrian-Vazquez, Jorge Omar Escobedo-Cordova, Mark Allen Lowry
  • Near-infrared fluorescent dyes with large stokes shifts
    Patent number: 9250246
    Abstract: Embodiments of near-infrared (NIR) dyes are disclosed, along with methods and kits for detecting analytes with the NIR dyes. The NIR dyes have a structure according to the general structure At least one of R1/R2, R2/R3, R3/R4, R5/R6, R6/R7, and/or R7/R8 together forms a substituted or unsubstituted cycloalkyl or aryl.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: February 2, 2016
    Assignee: Portland State University
    Inventors: Robert Michael Strongin, Martha Sibrian-Vazquez, Jorge Omar Escobedo-Cordova, Mark Allen Lowry
  • Thiol detection
    Patent number: 8927727
    Abstract: Embodiments of compounds for selectively detecting a thiol are disclosed. In some embodiments, the compounds are bridged viologens, and the compounds are capable of reacting with homocysteine and/or glutathione in a buffered solution to produce a change in the solution's absorbance spectrum and/or emission spectrum. Also disclosed are embodiments of methods and kits for detecting homocysteine and/or glutathione with the disclosed bridged viologens.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: January 6, 2015
    Assignee: The State of Oregon Acting by and through the State Board of Higher Education on behalf of Portland State University
    Inventors: Robert Michael Strongin, Martha Sibrian-Vazquez
  • ANALYTE DETECTION USING NEAR-INFRARED FLUOROPHORES
    Publication number: 20140127820
    Abstract: Embodiments of compounds for selectively detecting an analyte are disclosed, along with methods and kits for detecting analytes with the compounds. The compounds are bridged viologen conjugates including at least one fluorophore according to the general structure At least one of R1/R2, R2/R3, R3/R4, R5/R6, R6/R7, and/or R7/R8 together form a substituted or unsubstituted cycloalkyl or aryl.
    Type: Application
    Filed: June 29, 2012
    Publication date: May 8, 2014
    Applicant: The Oregon State Board of Higher Education on Behalf of Portland State University
    Inventors: Robert Michael Strongin, Martha Sibrian-Vazquez, Jorge Omar Escobedo-Cordova, Mark Allen Lowry
  • NEAR-INFRARED FLUORESCENT DYES WITH LARGE STOKES SHIFTS
    Publication number: 20140120628
    Abstract: Embodiments of near-infrared (NIR) dyes are disclosed, along with methods and kits for detecting analytes with the NIR dyes. The NIR dyes have a structure according to the general structure At least one of R1/R2, R2/R3, R3/R4, R5/R6, R6/R7, and/or R7/R8 together forms a substituted or unsubstituted cycloalkyl or aryl.
    Type: Application
    Filed: June 29, 2012
    Publication date: May 1, 2014
    Applicant: The Oregon State Board of Higher Education on Behalf of Portland State University
    Inventors: Robert Michael Strongin, Martha Sibrian-Vazquez, Jorge Omar Escobedo-Cordova, Mark Allen Lowry
  • THIOL DETECTION
    Publication number: 20120276649
    Abstract: Embodiments of compounds for selectively detecting a thiol are disclosed. In some embodiments, the compounds are bridged viologens, and the compounds are capable of reacting with homocysteine and/or glutathione in a buffered solution to produce a change in the solution's absorbance spectrum and/or emission spectrum. Also disclosed are embodiments of methods and kits for detecting homocysteine and/or glutathione with the disclosed bridged viologens.
    Type: Application
    Filed: June 29, 2012
    Publication date: November 1, 2012
    Inventors: Robert Michael Strongin, Martha Sibrian-Vazquez