Patents by Inventor Robert Mittler

Robert Mittler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polynucleotides encoding humanized antibodies against human 4-1BB
    Publication number: 20050202022
    Abstract: A humanized antibody that binds to human 4-1BB and that allows binding of human 4-1BB to a human 4-1BB ligand. In one aspect, the antibody is an IgG4 antibody. Also provided is a method for treating cancer in a subject comprising administering a therapeutically effective amount of the antibody to said subject.
    Type: Application
    Filed: March 7, 2005
    Publication date: September 15, 2005
    Inventors: Maria Kunkel, Subinay Ganguly, Ralph Abraham, Diane Hollenbaugh, Jill Rillema, Barbara Thorne, Walter Shuford, Robert Mittler
  • Modified sFv molecules which mediate adhesion between cells and uses thereof
    Patent number: 6699715
    Abstract: The modified sFv molecules of the present invention stimulate adhesion between cells thereby enhancing the immune response against disease. These molecules generally comprise an antigen binding site of an antibody and at least a portion of a transmembrane domain of a cell surface receptor.
    Type: Grant
    Filed: November 27, 1996
    Date of Patent: March 2, 2004
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Jeffrey A. Ledbetter, Martha Hayden, Perry Fell, Robert Mittler, Gosta Winberg