Patents by Inventor Robert Modlin

Robert Modlin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CONTROLLED RELEASE ENCAPSULATED ANTI-BACTERIAL AND ANTI-INFLAMMATORY NANOPARTICLES
    Publication number: 20110135742
    Abstract: This invention pertains to the formulation of nanoparticles that have intrinsic antimicrobial and anti-inflammatory activity. The nanoparticles can be impregnated with one or more therapeutic agents and thereby enhance the antimicrobial and/or anti-inflammatory activity of such agents, and also other properties that the therapeutic agents provide.
    Type: Application
    Filed: June 19, 2007
    Publication date: June 9, 2011
    Applicant: The Regents of the University of California
    Inventors: Jenny Kim, Adam Friedman, Robert Modlin
  • ANTIMICROBIAL THERAPY
    Publication number: 20100273748
    Abstract: Methods and compositions for modulating gene expression and the innate immune response by 1,25(OH)2 vitamin D3 (1,25D3) are provided. Also provided are methods and compositions for modulating histone acetylation using 1,25(OH)2 vitamin D3 (1,25D3).
    Type: Application
    Filed: September 7, 2007
    Publication date: October 28, 2010
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Richard L. Gallo, Jurgen Schauber, Robert Modlin
  • Granulysin peptides and methods of use thereof
    Publication number: 20060128623
    Abstract: Granulysin peptides are small antimicrobial agents with potent activity against bacteria and inflammation. A pharmaceutical composition comprising granulysin peptides as an active agent is administered therapeutically to a patient suffering from a microbial infection.
    Type: Application
    Filed: December 14, 2005
    Publication date: June 15, 2006
    Inventors: Robert Modlin, Jenny Kim, Daniel Anderson, David Eisenberg, Richard Gallo
  • Methods for stimulating tlr irf3 pathways for inducing anti-microbial, anti-inflammatory and anticancer responses
    Publication number: 20060057104
    Abstract: The present invention provides methods for stimulating Toll-like receptors (TLR) to activate IRF (e.g., an IRF3) and signaling pathway, and thereby directing an antimicrobial activity. The present invention also provides methods for identifying agents that bind and/or stimulate TLR and mediate induction of an IRF3 pathway, thereby directing an antimicrobial activity. Additionally, the invention provides methods and agents for suppressing stimulation of TLR, thereby directing an anti-inflammatory response.
    Type: Application
    Filed: April 24, 2003
    Publication date: March 16, 2006
    Applicant: THE Regents of the University of California Office of the President
    Inventors: Genhong Cheng, Robert Modlin, Sagar Vaidya, Sean Doyle