Abstract: A stable formulation of an anti-IL 13R antibody. Also provided is the use of this formulation for treatment, method of treatment using the formulation and a process of making the formulation.

Abstract: A system and method for selecting an intraocular lens, for implantation into an eye, includes a controller having a processor and a tangible, non-transitory memory on which instructions are recorded. The controller is configured to selectively execute a machine learning model trained with a training dataset. Execution of the instructions by the processor causes the controller to obtain pre-operative objective data for the patient, including one or more anatomic eye measurements. The controller is configured to obtain pre-operative questionnaire data for the patient, including at least one personality trait. The pre-operative objective data and the pre-operative questionnaire data are entered as respective inputs to the machine learning model. A predicted subjective outcome score for the patient is generated as an output of the machine learning model. The intraocular lens is selected based in part on the predicted subjective outcome score.

Abstract: A method of treating an autoimmune skin disease in a patient comprising administering a therapeutically effective amount of a DHODH inhibitor or a pharmaceutically acceptable salt thereof. Also provided are formulations or compositions suitable for treating autoimmune skin diseases.

Abstract: A system and method for selecting an intraocular lens, for implantation into an eye, includes a controller having a processor and a tangible, non-transitory memory on which instructions are recorded. The controller is configured to selectively execute a machine learning model trained with a training dataset. Execution of the instructions by the processor causes the controller to obtain pre-operative objective data for the patient, including one or more anatomic eye measurements. The controller is configured to obtain pre-operative questionnaire data for the patient, including at least one personality trait. The pre-operative objective data and the pre-operative questionnaire data are entered as respective inputs to the machine learning model. A predicted subjective outcome score for the patient is generated as an output of the machine learning model. The intraocular lens is selected based in part on the predicted subjective outcome score.

Abstract: Height adjustable seat posts for bicycles are described herein. An example seat post includes an upper tube and a lower tube are configured in a telescopic arrangement and moveable between at least a first position and a second position. The seat post includes an upper sealhead, a lower sealhead, a shaft coupled to the lower tube and extending through the lower sealhead and into the upper tube, and a piston in the upper tube and coupled to the shaft. The piston divides the upper tube into a first chamber between the piston and the upper sealhead and a second chamber between the piston and the lower sealhead. The seat post also includes a spacer in the second chamber between the piston and the lower sealhead to reduce a length of the height adjustable seat post in at least one of the first and second positions.

Abstract: The present disclosure relates to physical forms of a DHODH inhibitor, such as a stable crystalline form of and compositions comprising the same. Also provided is the use of the physical form (such as a polymorph) or composition thereof in treatment, such as the treatment of a viral disease or an autoimmune disease or disorder.

Abstract: Embodiments disclosed herein include a modular microwave source array. In an embodiment, a housing assembly for the source array comprises a first conductive layer, wherein the first conductive layer comprises a first coefficient of thermal expansion (CTE), and a second conductive layer over the first conductive layer, wherein the second conductive layer comprises a second CTE that is different than the first CTE. In an embodiment, the housing assembly further comprises a plurality of openings through the housing assembly, where each opening passes through the first conductive layer and the second conductive layer.

Abstract: A container and system for the mobile/portable heating of fluids is described. The container has an octahedral shape, including a pinched waist section. This pinched waist, along with the rounded corners at each edge of the octahedron, has a specific radius of curvature selected to maximize volumetric efficiency while still maintaining the ability to blow mold the container. One or more heating elements and attachment mechanism are also provided so that fluids in the container can be quickly and efficiently heated.

Abstract: This invention presents a method for the arrangement of information corresponding to a combination of treatments for electronic use, being derived from a method for the organization and storage of medicines and supplements in a storage organizer, which can be readily reviewed by patients and healthcare providers to facilitate Medication Therapy Management Services.

Abstract: A method of treating an autoimmune disease in a patient comprising administering a therapeutically effective amount of a DHODH inhibitor or a pharmaceutically acceptable salt thereof. Also provided are formulations or compositions suitable for treating autoimmune diseases.

Abstract: A method of treating an autoimmune skin disease in a patient comprising administering a therapeutically effective amount of a DHODH inhibitor or a pharmaceutically acceptable salt thereof. Also provided are formulations or compositions suitable for treating autoimmune skin diseases.

Abstract: Techniques involve an air flow assembly to provide pressurized air, e.g., for use by an air-cushion vehicle (ACV) or other craft. The air flow assembly includes a volute having a central chamber, a lift duct, and a thruster duct. The air flow assembly further includes a set of guide members disposed between the central chamber and the thruster duct, and linkage coupled to the set of guide members. The linkage is constructed and arranged to transition the set of guide members between a closed configuration in which the set of guide members closes an opening between the central chamber and the thruster duct, and an opened configuration in which the set of guide members opens the opening between the central chamber and the thruster duct.

Abstract: The present invention relates to an adjustable chair (10) comprising: a seat base (12) defining a seating surface portion (14) for receiving a user thereon in use, the seat base (12) comprising an integral seat back engagement portion (20) for engaging with a portion of a seat back (16), a seat front portion (40) opposing the seat back engagement portion (20), a first seat side portion and a second seat side portion opposing the first seat side portion, each of the first and second seat side portions located between the seat back engagement portion (20) and the seat front portion (40) and extending substantially transverse to the seat surface portion (14); and a seat back (16) having a seat base engagement portion (18) dimensioned to slidably engage with the seat back engagement portion (20) to form a seat back adjustment mechanism, wherein the seat back adjustment mechanism is located adjacent at least one of the first and second seat side portions and wherein the seat back adjustment mechanism is movable be

Abstract: Techniques involve an air flow assembly to provide pressurized air, e.g., for use by an air-cushion vehicle (ACV) or other craft. The air flow assembly includes a volute having a central chamber, a lift duct, and a thruster duct. The air flow assembly further includes a set of guide members disposed between the central chamber and the thruster duct, and linkage coupled to the set of guide members. The linkage is constructed and arranged to transition the set of guide members between a closed configuration in which the set of guide members closes an opening between the central chamber and the thruster duct, and an opened configuration in which the set of guide members opens the opening between the central chamber and the thruster duct.

Abstract: Embodiments disclosed herein include a modular microwave source array. In an embodiment, a housing assembly for the source array comprises a first conductive layer, wherein the first conductive layer comprises a first coefficient of thermal expansion (CTE), and a second conductive layer over the first conductive layer, wherein the second conductive layer comprises a second CTE that is different than the first CTE. In an embodiment, the housing assembly further comprises a plurality of openings through the housing assembly, where each opening passes through the first conductive layer and the second conductive layer.

Abstract: The present disclosure relates to a pharmaceutically acceptable salt of compounds (I), i.e. varlitinib, a method of producing the salt, a purer form of the free base obtainable from the salt, and a pharmaceutical composition comprising any one of the same. Also provided is a salt, free base or composition thereof for use in treatment, in particular the treatment of cancer, including as part of a combination therapy, for example in combination with a chemotherapeutic agent. The disclosure also extends to compositions comprising the same and use of any one of the same in treatment, in particular treatment of cancer.

Abstract: A system and method for selecting an intraocular lens, for implantation into an eye, includes a controller having a processor and a tangible, non-transitory memory on which instructions are recorded. The controller is configured to selectively execute a machine learning model trained with a training dataset. Execution of the instructions by the processor causes the controller to obtain pre-operative objective data for the patient, including one or more anatomic eye measurements. The controller is configured to obtain pre-operative questionnaire data for the patient, including at least one personality trait. The pre-operative objective data and the pre-operative questionnaire data are entered as respective inputs to the machine learning model. A predicted subjective outcome score for the patient is generated as an output of the machine learning model. The intraocular lens is selected based in part on the predicted subjective outcome score.

Abstract: The present disclosure provides methods for purifying a solution comprising cantharidin and cantharidin-associated impurities. A method to purify the solution can comprise recrystallization or sublimation, for example. The purified cantharidin can be analyzed using a detection method comprising a stationary phase and one or more mobile phases.

Abstract: A novel soybean variety, designated AV42705183 is provided. Also provided are the seeds of soybean variety AV42705183, cells from soybean variety AV42705183, plants of soybean AV42705183, and plant parts of soybean variety AV42705183. Methods provided include producing a soybean plant by crossing soybean variety AV42705183 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety AV42705183, methods for producing other soybean varieties or plant parts derived from soybean variety AV42705183, and methods of characterizing soybean variety AV42705183. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety AV42705183 are further provided.

Abstract: An equipment stand for storing police and/or military clothing and equipment may include a base; at least one upright extending upward from the base; a belt hanger supported by the upright and effective for holding an equipment belt; a vest hanger supported by the upright and effective for holding an equipment vest; a tray supported by the upright and effective for holding miscellaneous objects that do not need to be secured; and a lock box supported by the upright and effective for holding miscellaneous objects that may need to be secured. The stand may include an upright extension for holding one or more clothing hangers. The stand may be freestanding, or may be used without the base when mounted to a wall.