Abstract: Disclosed herein are proteins having at least 90% sequence identity to a wild-type human butyrylcholinesterase and compositions comprising same. The disclosed proteins may have at least one mutation at a position within the acyl binding pocket and at least one mutation adjacent to the acyl biding pocket. Further disclosed are proteins having at least 90% sequence identity to a wild-type human butyrylcholinesterase, wherein the protein may comprise a mutation at a position selected from one or more of 282, 283, and 284.

Abstract: Particular embodiments comprise providing a surface mesh for an object, generating a voxel grid comprising volumetric masks for the mesh, and generating a lit mesh, wherein the lit mesh comprises a shaded version of the mesh as positioned in a scene. The voxel grid may be positioned over the lit mesh in the scene, and a first ray may be traced to a position of the voxel grid. If the traced ray passed through the voxel grid and hit a location on the lit mesh, then one or more second rays may be traced to the hit location on the lit mesh. If the traced ray hit a location in the voxel grid but did not hit a location on the lit mesh, then one or more second rays may be traced from the hit location in the voxel grid to the closest locations on the lit mesh. Finally, color sampled at one or more locations proximate to the position of the voxel grid may be blurred outward through the voxel grid to create a volumetric projection.

Abstract: Particular embodiments comprise providing a surface mesh for an object, generating a voxel grid comprising volumetric masks for the mesh, and generating a lit mesh, wherein the lit mesh comprises a shaded version of the mesh as positioned in a scene. The voxel grid may be positioned over the lit mesh in the scene, and a first ray may be traced to a position of the voxel grid. If the traced ray passed through the voxel grid and hit a location on the lit mesh, then one or more second rays may be traced to the hit location on the lit mesh. If the traced ray hit a location in the voxel grid but did not hit a location on the lit mesh, then one or more second rays may be traced from the hit location in the voxel grid to the closest locations on the lit mesh. Finally, color sampled at one or more locations proximate to the position of the voxel grid may be blurred outward through the voxel grid to create a volumetric projection.

Abstract: A venous access device is generally discussed herein with particular discussions extended to port access device having a protective clip. The port access device includes a needle hub having a needle extending therefrom and a catheter hub having a catheter tube extending therefrom with the needle positioned inside the tube in a ready to use position. A tip protector is positioned inside a clip housing, which is positioned in between the catheter hub and the needle hub.

Abstract: A device and method of making a peel-away introducer sheath adapted for use in transcutaneous insertions of medical instrumentation according to an embodiment of the present invention includes, forming at least two anchor apertures in an end portion of a peel-away sheath tube, molding a fitting around the end portion by passing molten resin into a fitting mold and through the at least two anchor apertures, and cooling the resin within the mold and the at least two anchor apertures to thereby fasten the fitting to the sheath tube.

Abstract: A device and method of making a peel-away introducer sheath adapted for use in transcutaneous insertions of medical instrumentation according to an embodiment of the present invention includes, forming at least two anchor apertures in an end portion of a peel-away sheath tube, molding a fitting around the end portion by passing molten resin into a fitting mold and through the at least two anchor apertures, and cooling the resin within the mold and the at least two anchor apertures to thereby fasten the fitting to the sheath tube.

Abstract: A device and method of making a peel-away introducer sheath adapted for use in transcutaneous insertions of medical instrumentation according to an embodiment of the present invention includes, forming at least two anchor apertures in an end portion of a peel-away sheath tube, molding a fitting around the end portion by passing molten resin into a fitting mold and through the at least two anchor apertures, and cooling the resin within the mold and the at least two anchor apertures to thereby fasten the fitting to the sheath tube.

Abstract: A method and system for importing data comprising the downloading of product data from different sources and in different formats; processing the downloaded data by at least comparing it with data downloaded and stored in a product database; and reviewing the results of the comparison to detect differences in the data, the differences potentially being errors. The system and methods further comprise connecting the downloaded data from its supplier specific format into a standard format; comparing the downloaded data in the standard format with a previously downloaded data set saved in the standard format; categorizing the product data based on the results of the second comparison; and processing each category of data independently to automatically update the product database.

Abstract: A venous access device is generally discussed herein with particular discussions extended to port access device having a protective clip. The port access device includes a needle hub having a needle extending therefrom and a catheter hub having a catheter tube extending therefrom with the needle positioned inside the tube in a ready to use position. A tip protector is positioned inside a clip housing, which is positioned in between the catheter hub and the needle hub.

Abstract: A method and system for importing data comprising the downloading of product data from different sources and in different formats; processing the downloaded data by at least comparing it with data downloaded and stored in a product database; and reviewing the results of the comparison to detect differences in the data, the differences potentially being errors. The system and methods further comprise connecting the downloaded data from its supplier specific format into a standard format; comparing the downloaded data in the standard format with a previously downloaded data set saved in the standard format; categorizing the product data based on the results of the second comparison; and processing each category of data independently to automatically update the product database.

Abstract: A device and method of making a peel-away introducer sheath adapted for use in transcutaneous insertions of medical instrumentation according to an embodiment of the present invention includes, forming at least two anchor apertures in an end portion of a peel-away sheath tube, molding a fitting around the end portion by passing molten resin into a fitting mold and through the at least two anchor apertures, and cooling the resin within the mold and the at least two anchor apertures to thereby fasten the fitting to the sheath tube.

Abstract: A portable ladder platform having locking and leveling features. A platform is provided which attaches to a standard rung type ladder through brace members, one of which is hook shaped for placement over a rung, and another, which is pivotable, moves under the rung to prevent accidental dislodgement of the platform in use. A leveling device is provided which allows adjustment for varying ladder angles.