Abstract: This invention relates to a pharmaceutical formulation of a bispecific anti-VEGF/ANG2 antibody, and a process for the preparation and uses of the formulation.

Abstract: An integrated circuit module is provided for post-lamination implanting into a smartcard body. The integrated circuit module includes a contact plate, a biometric sensor, a secure element, and means for electrical connection to an antenna embedded within the smartcard body. The secure element includes contact and contactless communication logic, and is configured to perform at least one smartcard function utilising the biometric sensor.

Abstract: A structure for aligning a biometrically-authorisable smartcard with respect to a smartphone during biometric enrolment of the smartcard. The structure includes a smartcard area for receiving the smartcard and a guide for aligning the structure in a predetermined position with respect to the smartphone. The alignment structure is configured such that, when the smartcard is received in the smartcard area and the structure is aligned in the predetermined position with respect to the smartphone, the smartcard is located proximate a near field communication antenna of the smartphone such that the smartcard receives power from the antenna.

Abstract: This invention relates to a pharmaceutical formulation of a bispecific anti-VEGF/ANG2 antibody, and a process for the preparation and uses of the formulation.

Abstract: A device for heat treatment of materials and a method for thermal treatment of materials, which is carried out with the device according to the invention. Based on the invention, measurement data can be acquired with a high accuracy, where it is important that the device and the method are operated at very high temperatures. The method is preferably operated at a temperature >773.15 K (500° C.). In addition to the very high accuracy, the method also offers the possibility of acquiring and storing the measurement data during the performance of the method and then correlating it with performance data determined in downstream characterizations of the materials.

Abstract: In one embodiment, a sensor system includes an active thermal sensor pixel matrix, a plurality of presence sensors, and an image acquisition controller. The pixel matrix includes a plurality of pixels arranged in a plurality of rows and a plurality of columns and a boundary defining a perimeter. The plurality of presence sensors is disposed at least partially within the boundary of the pixel matrix. The image acquisition controller is coupled to the pixel matrix and the plurality of presence sensors. The image acquisition controller is configured to: (i) receive signals from the presence sensors; (ii) identify, based on the signals, a scan region, wherein the scan region is a portion of the pixel matrix that is in contact with or adjacent to a specimen; and (iii) obtain image data only from pixels that are within the scan region for generating an image of the specimen.

Abstract: An assembly comprising a smartcard (100) and a signal booster (200), wherein the smartcard comprises: an antenna (103) for contactless power harvesting; and a biometric capture device (102), wherein the smartcard is configured to perform biometric enrolment using the biometric capture device and to perform biometric authorisation using the biometric capture device after biometric enrolment has been completed, and wherein the signal booster (200) comprises: a first antenna (201) configured to inductively couple with the smartcard antenna (103), and a second antenna (202) configured to inductively couple with a near field communication antenna (302) of a smartphone (301), wherein the second antenna is smaller than the first antenna, and wherein the first and second antennas are in electrical communication such that power received via the second antenna from the antenna of the smartphone is transmitted via the first antenna to the antenna of the smartcard.

Abstract: An integrated circuit module is provided for post-lamination implanting into a smartcard body. The integrated circuit module includes a contact plate, a biometric sensor, a secure element, and means for electrical connection to an antenna embedded within the smartcard body. The secure element includes contact and contactless communication logic, and is configured to perform at least one smartcard function utilising the biometric sensor.

Abstract: An object of the present disclosure is to provide a staked-in needle prefilled syringe formulation containing an antibody engineered by a mutation to histidine, which reduces the difficulty in pushing out a drug and the risk of causing clogging in a needle. The staked-in needle prefilled syringe formulation can be produced by a simple method on an industrial scale. The present prefilled syringe formulation is characterized by having an elastomeric needle shield having a low zinc leaching capacity.

Abstract: A three-dimensional print head apparatus comprising a hopper, a nozzle, a barrel, a heating system, a fume extraction system, a dry air purge system, and an agitator. The hopper may having a cavity and may have a lower aperture. The nozzle may have an upper aperture and may have a lower aperture. The heating system may be positioned along at least a portion of the barrel, which may defined a heated zone of the barrel. The dry air purge system may be in fluid communication with the hopper. The agitator may have at least one paddle.

Abstract: A structure for aligning a biometrically-authorisable smartcard with respect to a smartphone during biometric enrolment of the smartcard. The structure includes a smartcard area for receiving the smartcard and a guide for aligning the structure in a predetermined position with respect to the smartphone. The alignment structure is configured such that, when the smartcard is received in the smartcard area and the structure is aligned in the predetermined position with respect to the smartphone, the smartcard is located proximate a near field communication antenna of the smartphone such that the smartcard receives power from the antenna.

Abstract: A three-dimensional print head apparatus including a hopper, a nozzle, a barrel, and a heating system. The apparatus may further include a fume extraction system and a dry air purge system. The hopper may have a cavity and a lower aperture. The nozzle may have an upper aperture and a lower aperture. The heating system may be positioned along the barrel, and the dry air purge system may be in fluid communication with the hopper.

Abstract: A three-dimensional print head apparatus may include a securing mechanism, a hopper, a nozzle, a heating system, and a fume extraction system. The securing mechanism may be adapted to secure to a wrist joint of a robotic arm. The hopper may have a cavity and a lower aperture and may be secured to the securing mechanism. The nozzle may have an upper aperture and a lower aperture. The heating system may be positioned along the barrel.

Abstract: In one embodiment, a sensor system includes an active thermal sensor pixel matrix, a plurality of presence sensors, and an image acquisition controller. The pixel matrix includes a plurality of pixels arranged in a plurality of rows and a plurality of columns and a boundary defining a perimeter. The plurality of presence sensors is disposed at least partially within the boundary of the pixel matrix. The image acquisition controller is coupled to the pixel matrix and the plurality of presence sensors. The image acquisition controller is configured to: (i) receive signals from the presence sensors; (ii) identify, based on the signals, a scan region, wherein the scan region is a portion of the pixel matrix that is in contact with or adjacent to a specimen; and (iii) obtain image data only from pixels that are within the scan region for generating an image of the specimen.

Abstract: A three-dimensional print head apparatus comprising a hopper, a nozzle, a barrel, a heating system, a fume extraction system, a dry air purge system, and an agitator. The hopper may having a cavity and may have a lower aperture. The nozzle may have an upper aperture and may have a lower aperture. The heating system may be positioned along at least a portion of the barrel, which may defined a heated zone of the barrel. The dry air purge system may be in fluid communication with the hopper. The agitator may have at least one paddle.

Abstract: A three-dimensional print head apparatus including a hopper, a nozzle, a barrel, and a heating system. The apparatus may further include a fume extraction system and a dry air purge system. The hopper may have a cavity and a lower aperture. The nozzle may have an upper aperture and a lower aperture. The heating system may be positioned along the barrel, and the dry air purge system may be in fluid communication with the hopper.

Abstract: In one embodiment, a sensor system includes an active thermal sensor pixel matrix, a plurality of presence sensors, and an image acquisition controller. The pixel matrix includes a plurality of pixels arranged in a plurality of rows and a plurality of columns and a boundary defining a perimeter. The plurality of presence sensors is disposed at least partially within the boundary of the pixel matrix. The image acquisition controller is coupled to the pixel matrix and the plurality of presence sensors. The image acquisition controller is configured to: (i) receive signals from the presence sensors; (ii) identify, based on the signals, a scan region, wherein the scan region is a portion of the pixel matrix that is in contact with or adjacent to a specimen; and (iii) obtain image data only from pixels that are within the scan region for generating an image of the specimen.

Abstract: The present invention comprises an interactive touch control for a pinball machine to allow a user to interact with various settings of a pinball game. The invention further comprises an improved glass top assembly to permit lifting of the glass top via a hinge near the back box. The invention further comprises an improved mechanism for locking the glass top assembly to the cabinet and locking the playfield to the cabinet.

Abstract: An interlocking paver system including a polygon paver and a spacer paver is provided. The polygon paver may have a top level having a top level polygon paver perimeter and a bottom level secured to and protruding from the top level and having a bottom level polygon paver perimeter contained within the top level polygon paver perimeter. The spacer paver may have a top level having a top level spacer paver perimeter and a bottom level secured to and protruding from the top level and having a bottom level spacer paver perimeter extending beyond an entirety of the top level spacer paver perimeter. The spacer paver may be configured to selectively interlock with the polygon paver. The top level spacer paver perimeter, top level polygon paver perimeter, and bottom level spacer paver perimeter are different from one another.

Abstract: A three dimensional printing system includes a light engine having a spatial light modulator for curing individual layers of a photocure resin to form a three dimensional article of manufacture. The light engine is configured to: (1) receive a slice image that defines an array of energy values for curing a layer, (2) process the slice image to define an image frame compatible with the spatial light modulator, (3) receive an on signal, (4) activate the first light source in response to the on signal; (5) repeatedly send the first defined image frame to the first spatial light modulator during a defined cure time for the single layer of resin; (6) receive an off signal; (7) deactivate the first light source in response to the off signal; and (8) repeat steps (1) - (7) until the three dimensional article of manufacture is formed.