Patents by Inventor Robert Murray Ratcliffe

Robert Murray Ratcliffe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds and methods for the treatment of bacterial dysentery using antibiotics and toxin binding oligosaccharide compositions
    Publication number: 20010018065
    Abstract: This invention relates to the treatment of diarrhea and related conditions caused by pathogenic E. coli infection. More specifically, this invention is drawn to the unexpected discovery that by administering a composition which binds and removes the shiga like toxins (SLT) produced by pathogenic E. coli whenever an antibiotic is administered, improved treatment is provided. Novel compositions containing both antibiotic and toxin binding composition and methods of treatment which use simultaneous administration toxin binding composition whenever antibiotic is administered are provided. These compositions and methods kill the enteric E. coli organisms which produce the conditions and neutralize the SLT produced by the organisms and/or released from the organisms when they are killed. Thus, these compositions and methods are better able to ameliorate the symptoms of the infection and inhibit progression of this infection into hemolytic uremic syndrome (HUS) than conventional treatment.
    Type: Application
    Filed: March 15, 2001
    Publication date: August 30, 2001
    Inventors: David John Rafter, Robert Murray Ratcliffe, Bradley G. Thompson, Glen D. Armstrong
  • Compounds and methods for the treatment of bacterial dysentery using antibiotics and toxin binding oligosaccharide compositions
    Patent number: 6224891
    Abstract: This invention relates to the treatment of diarrhea and related conditions caused by pathogenic E. coli infection. More specifically, this invention is drawn to the unexpected discovery that by administering a composition which binds and removes the shiga like toxins (SLT) produced by pathogenic E. coli whenever an antibiotic is administered, improved treatment is provided. Novel compositions containing both antibiotic and toxin binding composition and methods of treatment which use simultaneous administration toxin binding composition whenever antibiotic is administered are provided. These compositions and methods kill the enteric E. coli organisms which produce the conditions and neutralize the SLT produced by the organisms and/or released from the organisms when they are killed. Thus, these compositions and methods are better able to ameliorate the symptoms of the infection and inhibit progression of this infection into hemolytic uremic syndrome (HUS) than conventional treatment.
    Type: Grant
    Filed: February 23, 1999
    Date of Patent: May 1, 2001
    Assignee: Synsorb Biotech, Inc.
    Inventors: David John Rafter, Robert Murray Ratcliffe, Bradley G. Thompson, Glen D. Armstrong