Patents by Inventor Robert N Brey

Robert N Brey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Topically Active Steroids For Use in Radiation and Chemotherapeutics Injury
    Publication number: 20170333448
    Abstract: Methods of delivering corticosteroids or metabolites thereof for treating and preventing tissue damage resulting from acute radiation injury in the gastrointestinal tract with locally effective therapeutic agents.
    Type: Application
    Filed: April 24, 2017
    Publication date: November 23, 2017
    Inventors: Robert N Brey, Christopher Schaber, George McDonald
  • Polymerizable fatty acids, phospholipids and polymerized liposomes therefrom
    Patent number: 6511677
    Abstract: The invention relates to an oral drug delivery system which delivers biologically active substances to the mucosal tissue of the intestine utilizing novel polymerized liposomes. Novel polymerizable fatty acids having a polymerizable group, a surfactant group, and a functional group, and optionally coupled to ligands which target mucosal tissue in the intestine are disclosed. Novel negatively charged polymerizable lipids which have phosphatidyl inositol (PI), phosphatidyl glycerol (PG) or phosphatidyl serine (PS) groups on a polymerizable backbone are also described.
    Type: Grant
    Filed: November 17, 2000
    Date of Patent: January 28, 2003
    Assignee: Orasomol Technologies, Inc.
    Inventors: Robert N Brey, Likan Liang
  • Polymerizable fatty acids, phospholipids and polymerized liposomes therefrom
    Patent number: 6500453
    Abstract: The invention relates to an oral drug delivery system which delivers biologically active substances to the mucosal tissue of the intestine utilizing novel polymerized liposomes. Novel polymerizable fatty acids having a polymerizable group, a surfactant group, and a functional group, and optionally coupled to ligands which target mucosal tissue in the intestine are disclosed. Novel negatively charged polymerizable lipids which have phosphatidyl inositol (PI), phosphatidyl glycerol (PG) or phosphatidyl serine (PS) groups on a polymerizable backbone are also described.
    Type: Grant
    Filed: December 13, 2001
    Date of Patent: December 31, 2002
    Assignee: Orasomol Technologies, Inc.
    Inventors: Robert N Brey, Likan Liang
  • Polymerizable fatty acids, phospholipids and polymerized liposomes therefrom
    Patent number: 6187335
    Abstract: The invention relates to an oral drug delivery system which delivers biologically active substances to the mucosal tissue of the intestine utilizing novel polymerized liposomes. Novel polymerizable fatty acids having a polymerizable group, a surfactant group, and a functional group, and optionally coupled to ligands which target mucosal tissue in the intestine are disclosed. Novel negatively charged polymerizable lipids which have phosphatidyl inositol (PI), phosphatidyl glycerol (PG) or phosphatidyl serine (PS) groups on a polymerizable backbone are also described.
    Type: Grant
    Filed: December 31, 1997
    Date of Patent: February 13, 2001
    Assignee: Orasomal Technologies, Inc.
    Inventors: Robert N Brey, Likan Liang