Abstract: The present disclosure provides for the treatment of cardiac diseases and disorders using in vitro-differentiated cardiomyocytes. Such methods can take advantage of both autologous and allogeneic pluripotent stem cells.

Abstract: The present disclosure generally relates to, inter alia, to nucleic acid constructs encoding a modified enterovirus genome that is devoid of partial or complete nucleic acid sequences encoding viral structural proteins. The disclosure also provides compositions and methods useful for producing defective interfering particles (DIPs) of enteroviruses, and for the prevention and/or treatment of various health conditions such as immune diseases and viral infections.

Abstract: Provided herein, inter alia, are methods and compounds for treating an HIV infection.

Abstract: Provided herein, inter alia, are methods and compounds for treating an HIV infection.

Abstract: The present invention provides methods and compositions for regulating gene expression using transcription factors linked to proteins that localize to the transcriptional machinery.

Abstract: The present invention provides methods and compositions for regulating gene expression using transcription factors linked to proteins that localize to the transcriptional machinery.

Abstract: Apparatus for sharpening and or honing a multi-bladed razor cartridge including a sharpening member, a housing to secure the sharpening member. An aloe vera or soap solution dispenser provides a lubricant to the sharpening member to lubricate the razor and a housing to limit the travel of the razor on the sharpening member.

Abstract: A method for using large chambers, located deep within the earth, for the disposal of processed waste is disclosed. In this context, waste includes solid waste from sewage, and other organic-waste materials from urban, agricultural or industrial sources. These wastes will be processed by mechanical pulverization and hydration to produce a slurry, which will be injected into the well's chamber. The anaerobic condition in the chamber will be conducive to the production of gases, especially methane which will be harvested as a source of industrial fuel. Hydrogen, ammonia and other gases will also be harvested. This system will alleviate the acute problem of disposal of wastes from urban agricultural and industrial sources. It will decrease pollution of the air with greenhouse gases and pollution of the land area water with organic wastes and also release of disease-causing pathogens. The system may be adapted to facilitate the disposal of nuclear wastes.