Abstract: Systems and method relate to administering phototherapy. A device includes a hollow structure having at least a first open end. The hollow structure includes a rotatable member, one or more coherent light generators, and, for each coherent light generator, one or more lenses or mirrors optically connected to the coherent light generator and configured to alter at least one aspect of a beam of coherent light. The device further includes a processing circuit including a processor and a memory storing instructions. The instructions, when executed by the processor, cause the processor to accept an input from an operator and generate one or more beams of coherent light according to a plurality of settings configured to produce a therapeutic effect at a targeted treatment site. Additionally, the rotatable member is configured to be rotated to direct the one or more beams of coherent light to the targeted treatment site.

Abstract: Systems and method relate to administering phototherapy. A device includes a hollow structure having at least a first open end. The hollow structure includes a rotatable member, one or more coherent light generators, and, for each coherent light generator, one or more lenses or mirrors optically connected to the coherent light generator and configured to alter at least one aspect of a beam of coherent light. The device further includes a processing circuit including a processor and a memory storing instructions. The instructions, when executed by the processor, cause the processor to accept an input from an operator and generate one or more beams of coherent light according to a plurality of settings configured to produce a therapeutic effect at a targeted treatment site. Additionally, the rotatable member is configured to be rotated to direct the one or more beams of coherent light to the targeted treatment site.

Abstract: Systems and method relate to administering phototherapy. A device includes a hollow structure having at least a first open end. The hollow structure includes a rotatable member, one or more coherent light generators, and, for each coherent light generator, one or more lenses or mirrors optically connected to the coherent light generator and configured to alter at least one aspect of a beam of coherent light. The device further includes a processing circuit including a processor and a memory storing instructions. The instructions, when executed by the processor, cause the processor to accept an input from an operator and generate one or more beams of coherent light according to a plurality of settings configured to produce a therapeutic effect at a targeted treatment site. Additionally, the rotatable member is configured to be rotated to direct the one or more beams of coherent light to the targeted treatment site.

Abstract: A resistance system is disclosed. The resistance system has a line reel system for deploying a tension line and a power system for drawing in the slack line. The resistance value can be set by a subject using the device by using a resistance controller and indicator located on an outer surface of the system. The system can be self-contained with an internal power supply. The system is particularly useful for swim training or rehabilitation. It can be simply operated by a user without removing the device.

Abstract: Systems and method relate to administering phototherapy. A device includes a hollow structure having at least a first open end. The hollow structure includes a rotatable member, one or more coherent light generators, and, for each coherent light generator, one or more lenses or mirrors optically connected to the coherent light generator and configured to alter at least one aspect of a beam of coherent light. The device further includes a processing circuit including a processor and a memory storing instructions. The instructions, when executed by the processor, cause the processor to accept an input from an operator and generate one or more beams of coherent light according to a plurality of settings configured to produce a therapeutic effect at a targeted treatment site. Additionally, the rotatable member is configured to be rotated to direct the one or more beams of coherent light to the targeted treatment site.

Abstract: Ground vehicles that may include flight capability are described. In some examples, a vehicle frame may include a main support and at least two auxiliary supports, with the main support disposed substantially along the centerline of the vehicle, and the at least two auxiliary supports extending upward and outward from the main support. In some examples, vehicles may include an inflatable airfoil, such as a ram air parachute, that includes stiffeners on or about a leading edge of the airfoil. In some examples, vehicles may include a front wheelbase attached to the main support and/or auxiliary supports, a rear wheelbase attached to the main support and/or auxiliary supports, a ground steering mechanism connected to the front wheelbase and/or the rear wheelbase, a motor connected to a propeller, and a propeller shroud at least partially encircling the propeller.

Abstract: A ground vehicle with flight capability is described including a deployable airfoil configured to deploy from a stowed configuration to a deployed configuration, preferably during ground locomotion of the vehicle. The vehicle also includes a deployment mechanism for automatically deploying the airfoil from the stowed configuration to the deployed configuration. An automated retrieval mechanism may also be included for returning the airfoil to the stowed configuration. Also described are methods of transitioning a vehicle from ground locomotion to flight, including deploying a ram-air airfoil from a stowed configuration to a deployed configuration during ground locomotion of the vehicle.

Abstract: Composition and method for making a multi-layer bio-based film having one or more cavitated layers. In one aspect, the multilayer flexible film has polylactic acid, an inorganic filler, and a cavitation stabilizer making up at least one film layer. In one aspect, the barrier web has a cavitated bio-based film layer. In another aspect, the print web has a cavitated bio-based film layer.

Abstract: Ground vehicles that may include flight capability are described. In some examples, a vehicle frame may include a main support and at least two auxiliary supports, with the main support disposed substantially along the centerline of the vehicle, and the at least two auxiliary supports extending upward and outward from the main support. In some examples, vehicles may include an inflatable airfoil, such as a ram air parachute, that includes stiffeners on or about a leading edge of the airfoil. In some examples, vehicles may include a front wheelbase attached to the main support and/or auxiliary supports, a rear wheelbase attached to the main support and/or auxiliary supports, a ground steering mechanism connected to the front wheelbase and/or the rear wheelbase, a motor connected to a propeller, and a propeller shroud at least partially encircling the propeller.

Abstract: Air-ground vehicle fuel tank configurations and associated features are described that can be incorporated in the structural design of a vehicle in ways that improve both the ground mobility and flight capability of the vehicle. A vehicle frame may include a fuel tank with a main tank and two or more auxiliary tanks. The main tank may be disposed along the centerline of the vehicle, and the auxiliary tanks may extend upward and outward from the main tank, for example forming a “V” shape when viewed from the front. The auxiliary tanks may be substantially arc-shaped, when viewed from the side of the vehicle, and may be attached to the main tank at each end of the arc-shape. Each of the auxiliary tanks may include an attachment mechanism configured to attach to an airfoil suspension at or near an apex of the auxiliary tanks.

Abstract: Ground vehicles that may include flight capability are described. In some examples, a vehicle frame may include a fuel tank with a main tank and at least two auxiliary tanks, with the main tank disposed substantially along the centerline of the vehicle, and the at least two auxiliary tanks extending upward and outward from the main tank. In some examples, vehicles may include a chassis, a cage attached to the chassis, a front wheelbase attached to the chassis and/or cage, a rear wheelbase attached to the chassis and/or cage, a ground steering mechanism connected to the front wheelbase and/or the rear wheelbase, a motor connected to a propeller, and a propeller shroud at least partially encircling the propeller.

Abstract: A compressor mounting assembly that supports a variety of compressors and may be adapted to attach to a vehicle is disclosed herein. The compressor mounting assembly may contain structure that allows pivoting, rotation, and vertical adjustment to facilitate on-site testing, inspection, and/or manipulation of the compressor.

Abstract: Composition and method for making a multi-layer bio-based film having one or more cavitated layers. In one aspect, the multilayer flexible film has polylactic acid, an inorganic filler, and a cavitation stabilizer making up at least one film layer. In one aspect, the barrier web has a cavitated bio-based film layer. In another aspect, the print web has a cavitated bio-based film layer.

Abstract: Composition and method for making a multi-layer bio-based film having one or more cavitated layers. In one aspect, the multilayer flexible film has polylactic acid, an inorganic filler, and a cavitation stabilizer making up at least one film layer. In one aspect, the barrier web has a cavitated bio-based film layer. In another aspect, the print web has a cavitated bio-based film layer.

Abstract: Ground vehicles that may include flight capability are described. In some examples, a vehicle frame may include a fuel tank with a main tank and at least two auxiliary tanks, with the main tank disposed substantially along the centerline of the vehicle, and the at least two auxiliary tanks extending upward and outward from the main tank. In some examples, vehicles may include a chassis, a cage attached to the chassis, a front wheelbase attached to the chassis and/or cage, a rear wheelbase attached to the chassis and/or cage, a ground steering mechanism connected to the front wheelbase and/or the rear wheelbase, a motor connected to a propeller, and a propeller shroud at least partially encircling the propeller.

Abstract: Air-ground vehicle fuel tank configurations and associated features are described that can be incorporated in the structural design of a vehicle in ways that improve both the ground mobility and flight capability of the vehicle. A vehicle frame may include a fuel tank with a main tank and two or more auxiliary tanks The main tank may be disposed along the centerline of the vehicle, and the auxiliary tanks may extend upward and outward from the main tank, for example forming a “V” shape when viewed from the front. The auxiliary tanks may be substantially arc-shaped, when viewed from the side of the vehicle, and may be attached to the main tank at each end of the arc-shape. Each of the auxiliary tanks may include an attachment mechanism configured to attach to an airfoil suspension at or near an apex of the auxiliary tanks.

Abstract: The present invention provides a predictive biomarker whose expression level is useful for identifying patients responsive to a therapeutically effective dose of a CDK inhibitor. In one embodiment of the invention, the predictive biomarker is the ratio of MCL-1 to BCL-xL (MCL-1:BCL-xL ratio) and the CDK inhibitor is SCH 927965 (Dinaciclib).

Abstract: Composition and method for making a multi-layer bio-based film having one or more cavitated layers. In one aspect, the multilayer flexible film has polylactic acid, an inorganic filler, and a cavitation stabilizer making up at least one film layer. In one aspect, the barrier web has a cavitated bio-based film layer. In another aspect, the print web has a cavitated bio-based film layer.

Abstract: Medical devices, particularly stents, suitable for drug delivery and including a porous structure and/or colors are disclosed.

Abstract: The present invention is directed to methods, processes, and systems for delivering therapeutic agent to a medical device. Under some methods, processes, and systems of the invention, particles including a magnetic material and a therapeutic agent may be directed towards a medical device via magnetic attraction. In another embodiment particles including a magnetic material may force a therapeutic agent/solvent solution into porous matrix by using a magnetic attraction. In still another embodiment, a medical device having at least a portion thereof including a magnetic material is used to attract and adhere particles comprising magnetic material and therapeutic agent to a target surface of the medical device, wherein the particles are fused to the target surface.