Patents by Inventor Robert Nyfeler

Robert Nyfeler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5523311
    Abstract: A method and composition for the immunization of healthy useful plants against plant diseases containing as active ingredients compounds of formula ##STR1## in which: X is hydrogen, halogen, hydroxy, methyl, methoxy, HOOC or MOOC; Y is hydrogen, halogen, SO.sub.3 H, SO.sub.3 M, nitro, hydroxy or amino, M being the molar equivalent of an alkali metal or alkaline earth metal ion that is formed from a corresponding base or basic compound; and Z is cyano or --CO--A; A represents either --OH or --SH, the hydrogen atom of which may also be replaced by the molar equivalent of an inorganic or organic cationic residue, or wherein A represents any other organic residue which has a molecular weight of less than 900 and which may also contain one, or more than one, hetero atom, including the salts of the phytophysiologically tolerable 7-carboxylic acid or 7-thiocarboxylic acid with primary, secondary or tertiary amines or with inorganic bases.
    Type: Grant
    Filed: March 14, 1995
    Date of Patent: June 4, 1996
    Assignee: Ciba-Geigy Corporation
    Inventors: Rolf Schurter, Walter Kunz, Robert Nyfeler
  • Patent number: 5250557
    Abstract: The combination of the plant microbicide 4-(2,2-difluoro-1,3-benzodioxol-7-yl)-1H-pyrrole-3-carbonitrile with the plant microbicide 1-{2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-ylmethyl }-1H-1,2,4-triazole results in a synergistically increased effect in the control of plant diseases. Microbicidal compositions based on such combinations are suitable for treating crops of plants and natural products of vegetable and animal origin, and for seed treatment.
    Type: Grant
    Filed: November 15, 1991
    Date of Patent: October 5, 1993
    Assignee: Ciba-Geigy Corporation
    Inventors: Andrew Leadbeater, Bernhard Steck, Robert Nyfeler
  • Patent number: 5250556
    Abstract: The combination of the plant microbicide 4-(2,2-difluoro-1,3-benzodioxol-7-yl)-1H-pyrrole-3-carbonitril with the plant microbicide .alpha.-[2-(4-chlorophenyl)ethyl]-.alpha.-(1,1-dimethyl-ethyl)-.beta.-(1H- 1,2,4-triazolyl)-1-ethanol results in a synergistically enhanced effect in the control of plant diseases. Microbicidal compositions based on such combinations are suitable for treating natural products of vegetable and animal origin and, in particular, for seed treatment.
    Type: Grant
    Filed: November 13, 1991
    Date of Patent: October 5, 1993
    Assignee: Ciba-Geigy Corporation
    Inventors: Bernhard Steck, Robert Nyfeler
  • Patent number: 5190928
    Abstract: A method and composition for the immunization of healthy useful plants against plant diseases containing as active ingredients compounds of formula ##STR1## in which: X is hydrogen, halogen, hydroxy, methyl, methoxy, HOOC or MOOC;Y is hydrogen, halogen, SO.sub.3 H, SO.sub.3 M, nitro, hydroxy or amino, M being the molar equivalent of an alkali metal or alkaline earth metal ion that is formed from a corresponding base or basic compound; andZ is cyano or --CO--A;A represents either --OH or --SH, the hydrogen atom of which may also be replaced by the molar equivalent of an inorganic or organic cationic residue,or wherein A represents any other organic residue which has a molecular weight of less than 900 and which may also contain one, or more than one, hetero atom, including the salts of the phytophysiologically tolerable 7-carboxylic acid or 7-thiocarboxylic acid with primary, secondary or tertiary amines or with inorganic bases.
    Type: Grant
    Filed: April 10, 1991
    Date of Patent: March 2, 1993
    Assignee: Ciba-Geigy Corporation
    Inventors: Rolf Schurter, Walter Kunz, Robert Nyfeler
  • Patent number: 5135927
    Abstract: A microbicidal composition contains as active ingredient 2-chloro-4-trifluoromethylthiazol-5-carboxylic acid derivatives of the formula I ##STR1## R is an organic radical with up to 40 carbon atoms, which optionally contains nitrogen, oxygen or sulfur atoms and which can be transformed by hydrolosis or oxydation into the directly to the thiazol ring bound carboxyl rest.These compounds have good microbicidal activity and are used for the control and prevention of infestation of plants by phytophathogenic microorganismes.
    Type: Grant
    Filed: November 26, 1990
    Date of Patent: August 4, 1992
    Assignee: Ciba-Geigy Corporation
    Inventors: Werner Topfl, Robert Nyfeler, Werner Fory
  • Patent number: 5112849
    Abstract: 3-Cyano-4-(2,3-dichlorophenyl)pyrrole is suitable for controlling phytopathogenic microorganisms and is markedly superior in activity to preparation of a similar structure. Said compound may be employed for seed dressing, either along or in the form of compositions.
    Type: Grant
    Filed: May 18, 1990
    Date of Patent: May 12, 1992
    Assignee: Ciba-Geigy Corporation
    Inventors: Theodor Staub, Heide Dahmen, Robert Nyfeler, Robert J. Williams
  • Patent number: 5066661
    Abstract: The invention relates to novel N-(cyanomethyl)-benzo-1,2,3-thiadiazole-7-carboxamides of the formula I ##STR1## in which X.sub.1 and X.sub.2 independently of one another are hydrogen or 1 to 3 halogen; R is hydrogen C.sub.1 -C.sub.4 alkyl, C.sub.3 -C.sub.5 alkenyl or SR.sub.1 ; R.sub.1 is C.sub.1 -C.sub.3 alkyl which is substituted by 3 to 6 fluorine or chlorine; R.sub.2 is C.sub.1 -C.sub.4 alkyl, or is C.sub.1 -C.sub.5 alkyl which is interrupted by oxygen, or is C.sub.1 -C.sub.6 alkoxy, or is C.sub.1 -C.sub.3 alkyl which is substituted by 1 to 3 halogen, or is substituted C.sub.2 -C.sub.3 alkoxy, or is C.sub.1 -C.sub.6 alkylthio, or is furyl or thienyl, each of which is bonded in the 2- or 3-position, or is furyl or thienyl, each of which is substituted by 1 to 3 halogen and bonded in the 2- or 3-position; and R.sub.3 is hydrogen or C.sub.1 -C.sub.4 alkyl.Such compounds, by themselves or in the form of formulated agents, can be used for protecting plants against harmful microorganisms.
    Type: Grant
    Filed: March 6, 1990
    Date of Patent: November 19, 1991
    Assignee: Ciba-Geigy Corporation
    Inventors: Walter Kunz, Rolf Schurter, Robert Nyfeler
  • Patent number: 5036084
    Abstract: Pyridinyl derivatives of formula I ##STR1## wherein R.sub.1 to R.sub.5 are each independently hydrogen, halogen, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 haloalkyl, C.sub.1 -C.sub.6 alkoxy, C.sub.1 -C.sub.6 haloalkoxy, cyano, C.sub.1 -C.sub.6 alkoxycarbonyl or phenyl,R.sub.6 and R.sub.7 are each independently of the other hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.3 -C.sub.6 alkenyl or C.sub.3 -C.sub.6 alkynyl, or phenyl or benzyl, each of which is unsubstituted or substituted by halogen, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 haloalkyl, C.sub.1 -C.sub.6 alkoxy or C.sub.1 -C.sub.6 haloalkoxy,R.sub.8 is ##STR2## and R.sub.9 is hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.3 -C.sub.6 alkenyl, C.sub.3 -C.sub.6 alkynyl, or benzyl which is unsubstituted or substituted by halogen, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 haloalkyl, C.sub.1 -C.sub.6 alkoxy or C.sub.1 -C.sub.6 haloalkoxy, or R.sub.9 is an acyl radical.
    Type: Grant
    Filed: December 21, 1989
    Date of Patent: July 30, 1991
    Assignee: Ciba-Geigy Corporation
    Inventors: Hans Tobler, Peter Ackermann, Robert Nyfeler
  • Patent number: 4992434
    Abstract: A microbicidal compostion contains as active ingredient 2-chloro-4-trifluoromethylthiazol-5-carbonic acid derivatives of the formula I ##STR1## R is organic radical with up to 40 carbon atoms, which optionally contains nitrogen, oxygen or sulfur atoms and which can be transformed by hydrolosis or oxydation into the directly to the thiazol ring bound carboxyl rest. These compounds have good microbicidal activity and are used for the control and prevention of infestation of plants by phytophathogenic microorganisms.
    Type: Grant
    Filed: April 11, 1989
    Date of Patent: February 12, 1991
    Assignee: Ciba-Geigy Corporation
    Inventors: Werner Topfl, Robert Nyfeler, Werner Fory
  • Patent number: 4968344
    Abstract: A process for immunizing healthy plants against plant diseases which process comprises the dressing and/or coating of seeds or the treatment of plants and/or their environment by using active ingredients of the formula ##STR1## in which Hal is halogen,X is oxygen or sulfur, andR is hydrogen, C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.6 -alkyl which interrupted by an oxygen or sulfur atom, C.sub.1 -C.sub.6 -alkyl which is substituted by halogen, cyano or the COO--C.sub.1 -C.sub.6 -alkyl radical, C.sub.3 -C.sub.5 -alkenyl which is unsubstituted or substituted by halogen, C.sub.3 -C.sub.5 -alkynyl which is unsubstituted or substituted by halogen, C.sub.3 -C.sub.6 -cycloalkyl which is unsubstituted or substituted by halogen or methyl, or a normal equivalent of a cation which is formed from a base or a basic compound.
    Type: Grant
    Filed: October 31, 1989
    Date of Patent: November 6, 1990
    Assignee: Ciba-Geigy Corporation
    Inventors: Walter Kunz, Theodor Staub, Jean-Pierre M e/ traux, Karl Hoegerle, Robert Nyfeler, Patricia A. Ahl Goy
  • Patent number: 4945100
    Abstract: Essentially, a process is described for the preparation of the 1-triazolylethyl ether derivatives, defined in claim 1, of the general formula I ##STR1## which consists in (a) reacting an oxirane of the formula II ##STR2## at temperatures of -20.degree. to +100.degree. C., in the presence of an acid catalyst or an acid condensation agent, with an alcohol of the formula IIIR.sub.3 --OH (III)to give a glycol monoether of the formula IV ##STR3## and (b) subsequently reacting the glycol monoether of the formula IV or one of its esters, in the presence of an acid-binding agent or condensation agent, at temperatures of 0.degree. to 150.degree. C., with a triazole of the formula V ##STR4## the substituents R.sub.1, R.sub.2 ; amd R.sub.3 in the formula II to IV being as defined under formula I and M in formula V being hydrogen or a metal atom. The novel compounds within the scope of formula I and their use are also described.
    Type: Grant
    Filed: September 2, 1988
    Date of Patent: July 31, 1990
    Assignee: Ciba-Geigy Corporation
    Inventors: Robert Nyfeler, Helmut Zondler, Elmar Sturm
  • Patent number: 4931581
    Abstract: A method and composition for the immunization of healthy useful plants against plant diseases containing as active ingredients compounds of formula ##STR1## in which: X is hydrogen, halogen, hydroxy, methyl, methoxy, HOOC or MOOC;Y is hydrogen, halogen, SO.sub.3 H, SO.sub.3 M, nitro, hydroxy or amino, M being the molar equivalent of an alkali metal or alkaline earth metal ion that is formed from a corresponding base or basic compound; andZ is cyano or --CO--A;A represents either --OH or --SH, the hydrogen atom of which may also be replaced by the molar equivalent of an inorganic or organic cationic residue,or wherein A represents any other organic residue which has a molecular weight of less than 900 and which may also contain one, or more than one, hetero atom, including the salts of the phytophysiologically tolerable 7-carboxylic acid or 7-thiocarboxylic acid with primary, secondary or tertiary amines or with inorganic bases.
    Type: Grant
    Filed: August 18, 1988
    Date of Patent: June 5, 1990
    Assignee: Ciba-Geigy Corporation
    Inventors: Rolf Schurter, Walter Kunz, Robert Nyfeler
  • Patent number: 4925840
    Abstract: The invention relates to novel 3-phenyl-4-cyanopyrrole derivatives of the general formula ##STR1## wherein X has the following meanings:A: hydrogen or CO--R.sub.1, wherein R.sub.1 is C.sub.1 -C.sub.6 alkyl which is unsubstituted or substituted by halogen or C.sub.1 -C.sub.3 alkoxy; or is C.sub.3 -C.sub.6 alkenyl, C.sub.3 -C.sub.6 alkynyl, or C.sub.1 -C.sub.6 alkoxy which is unsubstituted or substituted by halogen or C.sub.1 -C.sub.3 alkoxy; or is C.sub.3 -C.sub.6 alkenyloxy, C.sub.3 -C.sub.6 cycloalkyl, or tetrahydrofur-2-yl;B: S--R.sub.2, wherein R.sub.2 is C.sub.1 -C.sub.3 haloalkyl;C: CH(Y)R.sub.3, wherein R.sub.3 is hydrogen or C.sub.1 -C.sub.8 haloalkyl and Y is hydroxy, halogen or OC(O)R.sub.4, wherein R.sub.4 is C.sub.1 -C.sub.8 alkyl, C.sub.1 -C.sub.8 haloalkyl, C.sub.2 -C.sub.6 alkenyl, or C.sub.1 -C.sub.6 alkoxycarbonyl; orD: CH.sub.2 --Z, wherein Z is the group ##STR2## wherein each of R.sub.7 and R.sub.8 independently of the other is hydrogen, C.sub.1 -C.sub.6 alkyl or C.sub.1 -C.sub.
    Type: Grant
    Filed: August 3, 1988
    Date of Patent: May 15, 1990
    Assignee: Ciba-Geigy Corporation
    Inventors: Robert Nyfeler, Josef Ehrenfraund
  • Patent number: 4925842
    Abstract: Combinations of the fungicides propiconazol and fenpropimorph, which belong to the group of inhibitors of ergosterol biosynthesis, exhibit synergistically enhanced activity against fungi. The active components may also be applied individually in immediate succession.
    Type: Grant
    Filed: March 28, 1988
    Date of Patent: May 15, 1990
    Assignee: Ciba-Geigy Corporation
    Inventors: Reinhard Janicke, Robert Nyfeler
  • Patent number: 4894380
    Abstract: The invention relates to 2-mercapto-5-pyridyl-1,3,4-oxadiazoles and 2-mercapto-5-pyridyl-1,3,4-thiadiazoles of the formula I ##STR1## wherein X is oxygen or sulfur,R' is C.sub.1 -C.sub.3 alkyl which is substituted by bromine, fluorine, C.sub.1 -C.sub.3 alkoxy or cyano; unsubstituted or halogen-substituted C.sub.3 -C.sub.7 alkenyl; unsubstituted or halogen-substituted C.sub.4 -C.sub.7 alkynyl,R is C.sub.1 -C.sub.3 alkyl, unsubstituted C.sub.1 -C.sub.3 alkoxy or C.sub.1 -C.sub.3 alkoxy which is substituted by halogen or C.sub.1 -C.sub.3 alkoxy; unsubstituted or halogen-substituted C.sub.3 -C.sub.7 alkenyl; C.sub.3 -C.sub.7 alkynyl, C.sub.1 -C.sub.3 alkylthio, halogen, cyano, hydroxy, amino or amino which is substituted by one or two C.sub.1 -C.sub.3 alkyl groups; or is aminocarbonyl; andn is 0, 1, 2, 3 or 4,to the preparation of the compounds of formula I and to novel intermediates for the synthesis of these compounds. The compounds of formula I have nematicidal properties.
    Type: Grant
    Filed: March 25, 1988
    Date of Patent: January 16, 1990
    Assignee: Ciba-Geigy Corporation
    Inventors: Robert Nyfeler, Wolfgang Eckhardt, Ernst Beriger, Odd Kristiansen
  • Patent number: 4861367
    Abstract: 2-Mercapto-5-pyrazinyl-1,3,4-oxadiazoles and 2-mercapto-5-pyrazinyl-1,3,4-thiadiazoles of formula I ##STR1## wherein X is oxygen or sulfur,R' is C.sub.1 -C.sub.5 alkyl, unsubstituted or substituted by halogen, C.sub.1 -C.sub.3 alkoxy or cyano; unsubstituted or halogen-substituted C.sub.3 -C.sub.7 alkenyl; unsubstituted or halogen-substituted C.sub.3 -C.sub.7 alkynyl,R is C.sub.1 -C.sub.3 alkyl, unsubstituted C.sub.1 -C.sub.3 alkoxy or C.sub.1 -C.sub.3 alkoxy which is substituted by halogen or C.sub.1 -C.sub.3 alkoxy; halogen, cyano, hydroxy, amino or amino which is substituted by one or two C.sub.1 -C.sub.3 alkyl groups; or is aminocarbonyl; andn is 0, 1, 2 or 3, the preparation thereof and novel intermediates for their synthesis are disclosed.The compounds of formula I have nematicidal properties. Nematicidal compositions which contain at least one compound of formula I as active ingredient, methods of using said compounds and of the compositions containing them for controlling nematodes are also disclosed.
    Type: Grant
    Filed: March 25, 1988
    Date of Patent: August 29, 1989
    Assignee: Ciba-Geigy Corporation
    Inventors: Robert Nyfeler, Wolfgang Eckhardt, Ernst Beriger
  • Patent number: 4861787
    Abstract: Novel compounds of the formula ##STR1## in which R' represents C.sub.1 -C.sub.5 -alkyl, halogen, trifluoromethyl or C.sub.1 -C.sub.3 -alkoxy;R" represents C.sub.1 -C.sub.5 -alkyl or halogen; andR"' represents C.sub.1 -C.sub.5 -alkyl that is unsubstituted or is substituted by from 1 to 6 halogen atoms, C.sub.1 -C.sub.5 -alkenyl that is unsubstituted or is substituted by from 1 to 6 halogen atoms, or C.sub.1 -C.sub.5 - alkynyl that is unsubstituted or is substituted by from 1 to 6 halogen atoms;m represents 0, 1, 2 or 3 andn represents 0 or 1; andX.sub.1 and X.sub.2 each represents, independently of the other, oxygen or sulphur,as active ingredients for controlling plant parasite nematodes and for preventing damage to cultivated plants caused by nematode attack.
    Type: Grant
    Filed: October 25, 1988
    Date of Patent: August 29, 1989
    Assignee: Ciba-Geigy Corporation
    Inventors: Ernst Beriger, Wolfgang Eckhardt, Robert Nyfeler
  • Patent number: 4851028
    Abstract: A method of combating undesirable plant growth and of regulating plant growth, which comprises allowing a herbicidal or plant-regulating amount of a compound of the formula I ##STR1## in which R.sub.1 is SR.sub.2 ; OR.sub.2 ; O--CHR.sub.10 R.sub.2 ; N(R.sub.3) (CHR.sub.10 R.sub.4); N(R.sub.11)(CHR.sub.10 R.sub.4) or NR.sub.3 R.sub.4 ; R.sub.2 is optionally substituted C.sub.1 -C.sub.10 -alkyl C.sub.1 -C.sub.4 -haloalkyl; C.sub.3 -C.sub.8 -alkenyl; (3-methyloxetan-3-yl)methyl; C.sub.3 -C.sub.8 -alkynyl; or an optionally substituted radical from the group comprising phenyl, benzyl, C.sub.3 -C.sub.7 -cycloalkyl, furanyl or furfuryl R.sub.3 and R.sub.4 independently of one another are hydrogen; an optionally substituted phenyl or benzyl radical; C.sub.1 -C.sub.8 -alkyl; or C.sub.3 -C.sub.6 -cycloalkyl; or R.sub.3 and R.sub.
    Type: Grant
    Filed: September 2, 1987
    Date of Patent: July 25, 1989
    Assignee: Ciba-Geigy Corporation
    Inventors: Helmut Zondler, Wolfgang Eckhardt, Robert Nyfeler, Hans-Georg Brunner
  • Patent number: 4849009
    Abstract: 2-Arylmethyliminopyrazines of the formula I ##STR1## in which R.sub.1 is SR.sub.2 ; OR.sub.2 ; O--CHR.sub.10 R.sub.2 ; N(R.sub.3)(CHR.sub.10 R.sub.4); N(R.sub.11)(CHR.sub.10 R.sub.4) or NR.sub.3 R.sub.4 ; R.sub.2 is C.sub.1 -C.sub.10 - alkyl which is unsubstituted or substituted by hydroxyl, mercapto, C.sub.1 -C.sub.4 -alkoxycarbonyl, mercaptoalkoxy, C.sub.1 -C.sub.4 -alkoxy, C.sub.1 -C.sub.4 -alkylcarbonyl, mono- or di-C.sub.1 -C.sub.4 -alkylamino, C.sub.1 -C.sub.4 -haloalkoxy, tri-(C.sub.1 -C.sub.4 -alkoxy)-silyl, cyano, nitro or phenyl; C.sub.1 -C.sub.4 -haloalkyl; C.sub.3 -C.sub.8 -alkenyl; (3-methyl-oxetan-3-yl)methyl; C.sub.3 -C.sub.8 -alkynyl; or a radical from the group comprising phenyl, benzyl, C.sub.3 -C.sub.7 -cycloalkyl, furanyl or furfuryl which is unsubstituted or mono-, di- or trisubstituted by identical or different substituents from the group comprising halogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkylcarbonyl, nitro, C.sub.1 -C.sub.4 -alkoxy and C.sub.1 -C.sub.4 -haloalkyl; R.sub.
    Type: Grant
    Filed: September 2, 1987
    Date of Patent: July 18, 1989
    Assignee: Ciba-Geigy Corporation
    Inventors: Helmut Zondler, Wolfgang Eckhardt, Robert Nyfeler
  • Patent number: 4840662
    Abstract: The invention discloses novel N-(2-nitrophenyl)-5-aminopyrimidine derivatives of the general formula ##STR1## wherein R.sub.1 and R.sub.2 are each independently NO.sub.2 or CF.sub.3, or one of R.sub.1 and R.sub.2 is hydrogen,R.sub.3 is hydrogen or halogen,R.sub.4 is hydrogen or the --C(O)R' group, in which R' is C.sub.1 -C.sub.4 alkyl which is unsubstituted or substituted by halogen, C.sub.1 -C.sub.3 alkoxy or C.sub.1 -C.sub.3 alkylthio,R.sub.5, R.sub.6 and R.sub.7 are each independently hydrogen, halogen, nitro, cyano, thiocyano, mercapto, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 haloalkyl, C.sub.1 -C.sub.6 alkoxy, C.sub.1 -C.sub.6 alkoxy which is substituted by halogen, nitro, cyano, C.sub.1 -C.sub.3 alkoxy, C.sub.1 -C.sub.3 alkylthio and/or N(C.sub.1 -C.sub.4 alkyl).sub.2 ; or are C.sub.3 -C.sub.6 cycloalkoxy, C.sub.3 -C.sub.6 alkenyloxy, C.sub.3 -C.sub.6 alkynyloxy, C.sub.1 -C.sub.6 alkylthio, C.sub.3 -C.sub.6 alkenylthio, C.sub.1 -C.sub.6 alkylsulfonyl, C.sub.1 -C.sub.6 alkylsulfoxyl, C.sub.3 -C.sub.
    Type: Grant
    Filed: July 16, 1984
    Date of Patent: June 20, 1989
    Assignee: Ciba-Geigy Corporation
    Inventors: Helmut Zondler, Adolf Hubele, Robert Nyfeler