Abstract: The present invention features a safety seal for a liquid spray dispensing assembly consisting of a sprayer mechanism and a container. A typical spray dispensing assembly has a container with a threaded cylindrical neck defining a container opening, and a sprayer mechanism with a pump mounted onto a threaded cap and a dip tube which extends into the container when the cap is threadedly secured to the neck of the container. Liquid is drawn from the container through the dip tube by operating the pump. The safety seal has a flange portion, a first sealing portion and a second sealing portion. The flange portion is insertable into the cap for contact with the rim of the neck when the cap is secured to the exterior surface of the neck. The flange retains the seal within the container opening. The first sealing portion extends from the flange and provides a frictional circumferential seal with the interior surface of the neck adjacent the neck rim.