Abstract: The invention relates to a method of detecting chromosomal abnormalities, in particular, the invention relates to the diagnosis of fetal chromosomal abnormalities such as trisomy 21 (Down's syndrome) which comprises sequence analysis of cell-free DNA molecules in plasma samples obtained from maternal blood during gestation of the fetus.

Abstract: The present invention relates to uses and methods for the detection of a quantitative difference between first and second target sequence regions present in a nucleic acid sample, in particular but not exclusively a DNA sample, and a kit for carrying out the uses and methods of the invention.

Abstract: An arrangement in a building control system includes a plurality of field panel devices. Each field panel device is configured to receive control inputs and further configured to provide control outputs to at least one building control device. Each field panel device includes a data store, a communication circuit, and a processing circuit. The data store maintains a set of global data that is shared by all field panel devices. The communication circuit is operably connected to others of the plurality of field panel devices via a logical network. The processing circuit is operable to communicate changes of any of the set of global data to at least one other field panel device via the communication circuit.