Abstract: The immune response to melanoma cells and tumors can be induced or significantly increased by administering to a subject a pharmaceutical composition comprising alphavirus particles, especially Venezuelan equine encephalitis virus replicon particles, which express the melanoma antigen dopachrome tautomerase (DCT, TRP2) in cells of the subject, with the result of tumor regression and/or inhibition of metastasis of a melanoma subject, or a decreased risk of the occurrence or recurrence of melanoma and/or decreased severity of melanoma in a subject not suffering from melanoma at the time of administration. The pharmaceutical composition described herein can be used in conjunction with other therapeutic agents, it can be administered on more than one occasion and it can be combined with administrations of other compositions such as protein or other immunogenic compositions, and/or adjuvants, with beneficial effects to the human or animal subject to which it has been administered.

Abstract: The immune response to melanoma cells and tumors can be induced or significantly increased by administering to a subject a pharmaceutical composition comprising alphavirus particles, especially Venezuelan equine encephalitis virus replicon particles, which express the melanoma antigen dopachrome tautomerase (DCT, TRP2) in cells of the subject, with the result of tumor regression and/or inhibition of metastasis of a melanoma subject, or a decreased risk of the occurrence or recurrence of melanoma and/or decreased severity of melanoma in a subject not suffering from melanoma at the time of administration. The pharmaceutical composition described herein can be used in conjunction with other therapeutic agents, it can be administered on more than one occasion and it can be combined with administrations of other compositions such as protein or other immunogenic compositions, and/or adjuvants, with beneficial effects to the human or animal subject to which it has been administered.

Abstract: A support assembly for a barrier movable between open and closed positions over an opening comprises a track. The track is attached to the wall for guiding movement of the barrier between substantially vertical closed position and a substantially horizontal open position. A jack shaft assembly is attached to the track and to the barrier for movement thereof. A mounting assembly is attached to the track for receiving a drive unit comprising a motor for supplying power to the jack shaft assembly to move the barrier and for limiting rotational movement of the drive unit.

Abstract: The present invention provides methods and compositions comprising a population of alphavirus replicon particles comprising alphavirus replicon RNAs, wherein a first replicon RNA comprises nucleic acid encoding cytomegalovirus pp65 and IE1 protein or immunogenic fragments thereof, and a second replicon RNA comprises nucleic acid encoding cytomegalovirus gB protein or an immunogenic fragment thereof, and wherein each of the two replicon RNAs is contained within a separate alphavirus replicon particle.

Abstract: A support assembly for a barrier movable between open and closed positions over an opening comprises a track. The track is attached to the wall for guiding movement of the barrier between substantially vertical closed position and a substantially horizontal open position. A jack shaft assembly is attached to the track and to the barrier for movement thereof. A mounting assembly is attached to the track for receiving a drive unit comprising a motor for supplying power to the jack shaft assembly to move the barrier and for limiting rotational movement of the drive unit.

Abstract: An apparatus and a method for quick mounting of a barrier operator on a ground surface is disclosed. The apparatus includes a mounting frame positioned on the ground and mounting structure extending into the ground surface. Concrete may then be poured into the mounting frame to form an operator support on which the barrier operator is mounted. The mounting structure may be a mounting post received in an excavated portion of the ground, and the mounting post and excavated portion may then be filled with concrete. The concrete in the frame, mounting post, and mounting frame may communicate as to form a unitary mass with the mounting frame and mounting post. The mounting structure may be mounting rods secured directly with the ground. The mounting rods have a spiral flute for driving into and securing with the ground.

Abstract: A barrier movement or garage door operator has a jack shaft connected to an output shaft delivering power to move a barrier or garage door between open and closed positions, the jack shaft and output shaft being connected by a coupling. The coupling, jack shaft, and output shaft are fixed relative to each other. The coupling connects the jack shaft and output shaft for rotation around a common axis. The coupling receives a portion of the jack shaft and output shaft for securing the shafts within the coupling by compressing against an outer surface of each shaft. The shafts may be cylindrical, and the compressive force may be distributed around the cylindrical outer surface of the shafts. The coupling may have a portion sized to correspond to respective predetermined diameters or sizes of the shafts.

Abstract: One or more optical signals (wherein at least some of a plurality of optical signals are at different angles of travel with respect to one another and are directed towards an area comprising a movable barrier-controlled point of passage) create reflections when striking passageway boundaries as correspond to a given movable barrier. Obstacles in the pathway also give rise to reflections. By determining a time-of-flight for such reflections, one can detect a likely presence of an obstacle in such a pathway. Pursuant to one approach, such time-of-flight information can further provide information regarding a likely size of such an obstacle.

Abstract: A packaging system is provided for facilitating transport of a moveable barrier operator. The packaging system comprises a generally rectangular container having a top wall, a bottom wall, a front wall, a rear wall, and two side walls defining an interior compartment. A handle is coupled to the top wall for movement between an extended position and a retracted position within the interior compartment. A wheel mount is coupled to the bottom wall, and at least one wheel is mounted on the wheel mount.

Abstract: A barrier movement operator with improved mounting and power distribution capabilities is disclosed. The disclosed system includes an elongate member mounted from an overhead structure in a substantially horizontal manner. A head end of a barrier movement operator may be supported by the elongate member and the elongate member may be used to mount accessory devices such as lights and extension cords, and to provide mains voltage to the mounted accessories.

Abstract: A barrier movement operator having an integrated mains voltage connection with a selective connection of power to an accessory such as a light is disclosed.

Abstract: A movable barrier operator system operational component includes an integral display comprising at least one of a numeric display, an alphanumeric display, and a graphics display. The display can comprise an active display or an active interactive display and can further operate in conjunction with adjacent user-input interface opportunities. So configured, numerous user interface events can be highly leveraged to contribute to ease of installation and ease and reliability of use.

Abstract: A barrier operator comprises a current limit portion and a barrier operator portion. The current limit portion is coupled to a mains supply and the barrier operator position is coupled to the mains supply and the current limit portion. The barrier operator portion actuates a movable barrier. The current limit portion regulates electrical current to at least one additional device.

Abstract: The present invention provides methods and compositions comprising a population of alphavirus replicon particles comprising two or more isolated nucleic acids selected from 1) an isolated nucleic acid encoding an env gene product or an immunogenic fragment thereof of a human immunodeficiency virus, 2) an isolated nucleic acid encoding a gag gene product or an immunogenic fragment thereof of a human immunodeficiency virus, wherein the gag gene product or immunogenic fragment thereof is modified to inhibit formation of virus-like particles containing the gag gene product or the immunogenic fragment thereof and their release from a cell, and 3) an isolated nucleic acid encoding a pol gene product or an immunogenic fragment thereof of a human immunodeficiency virus, wherein the pol gene product or immunogenic fragment thereof is modified to inhibit protease, integrase, RNase H and/or reverse transcriptase activity, and wherein the nucleic acids are each contained within a separate alphavirus replicon particle.

Abstract: The present invention provides methods and compositions comprising a population of alphavirus replicon particles comprising alphavirus replicon RNAs, wherein a first replicon RNA comprises nucleic acid encoding cytomegalovirus pp65 and IE1 protein or immunogenic fragments thereof, and a second replicon RNA comprises nucleic acid encoding cytomegalovirus gB protein or an immunogenic fragment thereof, and wherein each of the two replicon RNAs is contained within a separate alphavirus replicon particle.

Abstract: The present invention provides methods and compositions comprising a population of alphavirus replicon particles comprising two or more isolated nucleic acids selected from 1) an isolated nucleic acid encoding an env gene product or an immunogenic fragment thereof of a human immunodeficiency virus, 2) an isolated nucleic acid encoding a g&agr;g gene product or an immunogenic fragment thereof of a human immunodeficiency virus, wherein the g&agr;g gene product or immunogenic fragment thereof is modified to inhibit formation of virus-like particles containing the g&agr;g gene product or the immunogenic fragment thereof and their release from a cell, and 3) an isolated nucleic acid encoding a pol gene product or an immunogenic fragment thereof of a human immunodeficiency virus, wherein the pol gene product or immunogenic fragment thereof is modified to inhibit protease, integrase, RNase H and/or reverse transcriptase activity, and wherein the nucleic acids are each contained within a separate alphavirus replicon

Abstract: A multi-strand chain forms a chain drive including at least two chains so that the chain drive may communicate a force when the chain is pushed or pulled. The chains may be separated or disengage so as to be stored compactly. The chains may be engaged to form the chain drive so that the chain drive is substantially rigid and in a linear orientation, and pivotally connected chain links may not substantially rotate relative to each other and may not be deflected substantially from the linear orientation. The chains may be engaged and disengaged by rotating around sprockets which deliver the force to the chain drive. The chain drive may be utilized as a garage door system for raising or moving laterally a garage door or movable barrier with the chain drive in compression.

Abstract: The present invention provides methods and compositions comprising a population of alphavirus replicon particles comprising two or more isolated nucleic acids selected from 1) an isolated nucleic acid encoding an env gene product or an immunogenic fragment thereof of a human immunodeficiency virus, 2) an isolated nucleic acid encoding a gag gene product or an immunogenic fragment thereof of a human immunodeficiency virus, wherein the gag gene product or immunogenic fragment thereof is modified to inhibit formation of virus-like particles containing the gag gene product or the immunogenic fragment thereof and their release from a cell, and 3) an isolated nucleic acid encoding a pol gene product or an immunogenic fragment thereof of a human immunodeficiency virus, wherein the pol gene product or immunogenic fragment thereof is modified to inhibit protease, integrase, RNase H and/or reverse transcriptase activity, and wherein the nucleic acids are each contained within a separate alphavirus replicon particle.

Abstract: A data communication system providing for the secure transfer and sharing of data via a local area network and/or a wide area network. The system includes a secure processing unit which communicates with a personal keying device and a crypto media controller attached to a user's Workstation. The communication between these processing elements generates a variety of data elements including keys, identifiers, and attributes. The data elements are used to identify and authenticate the user, assign user security access rights and privileges, and assign media and device attributes to a data access device according to a predefined security policy. The data elements are manipulated, combined, protected, and distributed through the network to the appropriate data access devices, which prevents the user from obtaining unauthorized data.

Abstract: A method and apparatus for controlling model vehicles in a manner which accurately simulates the operation of real vehicles. Parameters relating to operational characteristics of a vehicle, environmental conditions, loading conditions, operator control settings, and physical characteristics of a controllable model are processed by a computer to determine appropriate control functions to a model allowing it to accurately replicate the operation of a real vehicle operating under the same set of conditions.