Abstract: The subject matter described herein presents various technical solutions for the technical problems facing autonomous vehicles (e.g., fully autonomous and semi-autonomous vehicles). To address technical problems facing wireless communication cost and latency, a heterogeneous roadside infrastructure can be used to improve the ability for a vehicle to communicate with a data source. To address technical problems facing interruption of vehicle services due to an abrupt loss of connection, a quality of service system provides the ability to determine and share quality of service information, such as location-based information, maps, interference data, and other quality of service information. To address technical problems facing high volume data upload and download between autonomous vehicles and cloud-based data services, optical wireless communication (OWC) provides increased data throughput and reduced complexity, and may be beneficial for short-range high-mobility wireless communications.

Abstract: This invention provides a method of reducing viral load in an HIV-1-infected human subject which comprises administering to the subject an effective HIV-1 viral load reducing dose of a CCR5 receptor antagonist, such as a humanized antibody designated PRO 140 or an anti-CCR5 receptor monoclonal antibody, wherein the viral load reducing dose achieves an average maximum decrease of viral load in the subject of at least 1.83 log10 to 2.5 log10 at about ten days following administration of the CCR5 receptor antagonist and wherein the viral load reducing dose further achieves a mean viral load reduction of 1.7 log10 at about nine days following administration of the CCR5 receptor antagonist. The viral load reducing dose results in a suppression of mean viral load by 1.0 log10 within about four days following administration of the CCR5 receptor antagonist, and suppression of viral load in the subject persists at or below a level of reduction of 1.0 log10 for about two to three weeks.

Abstract: The present invention is directed to kinase inhibitor compounds having the following structure: or a stereoisomer, pharmaceutically acceptable salt, oxide, or solvate thereof, where R1, R2, X, n, R3, Y, Z, R4, R5, R6, and = are as defined herein. The present invention also relates to compositions containing the kinase inhibitor compounds, methods of inhibiting activity of a kinase in a cell, methods of increasing cell proliferation in a population of pancreatic beta cells, methods of treating a subject for a condition associated with insufficient insulin secretion, and methods of treating a subject for a neurological disorder.

Abstract: A bar connector comprises an elongate bar with a series of electrical attachment structures along a length of the elongate bar. Each wire electrical attachment structure is to secure at least one wire to the elongate bar. A flexible connector wire with two ends that connect to the elongate bar is used to establish an electrical connection between the at least one wire and a secondary distribution line by a crimp connector. A method of connecting an electrical wire with the bar connector is also claimed.

Abstract: Disclosed is a process for the alkylation of an aliphatic organic compound comprising: (a) providing a catalyst comprising one or more zeolitic materials having a BEA framework structure, wherein the BEA framework structure comprises YO2 and optionally comprises X2O3, wherein Y is a tetravalent element, and X is a trivalent element, (b) contacting the catalyst with one or more aliphatic organic compounds in the presence of one or more alkylating agents in one or more reactors for obtaining one or more alkylated organic compounds, wherein the one or more zeolitic materials are obtainable from a synthetic process which does not employ an organotemplate as structure directing agent.

Abstract: A mobile salon vehicle is configured to contain a plurality of spa chairs with an integrated massaging foot spa tub. The mobile salon vehicle includes a generator, a water tank, a water heater, water pump and associated plumbing to service the massaging foot spa tubs. The salon chair may include a full service reclining massaging chair to provide salon services on the go.

Abstract: Method and apparatus are disclosed for initiation of vehicle remote park-assist with key fob. An example vehicle includes a cabin, a human-machine interface (HMI) unit located in the cabin, and a receiver-transceiver module. The receiver-transceiver module is configured to receive a return signal including a distance indicator from a key fob and a remote park-assist (RePA) signal. The example vehicle also includes an autonomy unit configured to perform RePA based on the RePA signal. The example vehicle also includes a controller configured to receive, via the HMI unit, selections to activate RePA and utilize the key fob for transmitting the RePA signal and determine, based on the distance indicator, whether the key fob is in the cabin. The controller also is configured to, responsive to determining that the key fob is in the cabin, prevent the autonomy unit from performing RePA.

Abstract: Described are dissolvable, porous solid structures formed using certain vinyl acetate-vinyl alcohol copolymers. The copolymer and the porosity of the structure allow for liquid flow during use such that the structure readily dissolves to provide a desired consumer experience. Also described are processes for making open cell foam and fibrous dissolvable solid structures.

Abstract: An adaptive seat configuration system and method are configured to adaptively determine a seat configuration for an internal cabin of an aircraft. The adaptive seat configuration system and method include a seat configuration analysis control unit that receives seat configuration data from one or more sources. The seat configuration analysis control analyzes the seat configuration data and determines the seat configuration for the internal cabin of the aircraft.

Abstract: A printhead for an additive manufacturing system includes a hopper, an outlet, a mixing shaft, and a drive shaft. The hopper includes an inner volume configured to store a slurry material for mixing. The outlet includes a passageway fluidly coupled with the hopper. The outlet includes an open end for discharging the slurry material to a surface through the passageway. The mixing shaft extends through the inner volume of the hopper and includes a member that extends radially outwards from the mixing shaft. The member is configured to mix the slurry material within the hopper as the mixing shaft rotates. The drive shaft extends through the inner volume of the hopper and at least partially into the passageway of the outlet. The drive shaft includes a sloped surface configured to drive the slurry material from the hopper to the surface through the passageway of the outlet.

Abstract: A storage system and a load handling device for lifting and moving containers stacked in the storage system are described. The storage system includes a plurality of rails or tracks arranged in a grid pattern above the stacks of containers. The grid pattern can include a plurality of grid spaces and each stack is located within a footprint of only a single grid space. The load handling device is configured to move laterally on the rails or tracks above the stacks. The load-handling device includes a container-receiving space located above the rails or tracks in use and a lifting device arranged to lift a container from a stack into the container-receiving space. The load handling device has a footprint that, in use, occupies only a single grid space in the storage system.

Abstract: Distributed system controllers provide on-demand data access in complex, heterogenous data storage. In one embodiment, the distributed system controllers respond to name space metadata event messages published on a persistent message but to maintain a common name space in a complex of heterogenous data storage systems. In one embodiment, data unit access request metadata messages are propagated in recursive, cascading hops along a persistent message bus until the requested data unit is located and retrieved. Other features and aspects may be realized, depending upon the particular application.

Abstract: Embodiments of secondary batteries having electrode assemblies are provided. A secondary battery can comprise an electrode assembly having a stacked series of layers, the stacked series of layers having an offset between electrode and counter-electrode layers in a unit cell member of the stacked series. A set of constraints can be provided with a primary constraint system with first and second primary growth constraints separated from each other in a longitudinal direction, and connected by at least one primary connecting member, and a secondary constraint system comprises first and second secondary growth constraints separated in a second direction and connected by members of the stacked series of layers. The primary constraint system may at least partially restrain growth of the electrode assembly in the longitudinal direction, and the secondary constraint system may at least partially restrain growth in the second direction that is orthogonal to the longitudinal direction.

Abstract: A method may include obtaining, from one of the rules of a static analysis, a built-in path relation describing a path constraint on a path variable, generating, using the rules, a transfer function that updates a property vector while analyzing code, generating an evaluation function that determines, using the updated property vector, whether the static analysis is satisfied, and determining whether the code includes a defect by executing the static analysis on the code using the path constraint, the transfer function, and the evaluation function.

Abstract: The compositions and methods described herein include methods and agents that inhibit inflammasome signaling in a mammal such as antibodies directed against inflammasome components used alone or in combination with extracellular vesicle uptake inhibitor(s) or other agents. Also described herein are compositions and methods of use thereof for treating viral-associated lung inflammation, for example lung inflammation associated with viral infections such as SARS-CoV-2.

Abstract: Method and apparatus are disclosed for key fob utilization for vehicle remote park-assist. An example vehicle system for remote park-assist (RePA) includes a key fob. The key fob includes a low frequency (LF) antenna to receive a beacon and an ultra-high frequency (UHF) antenna to transmit a return signal including a distance indicator and a RePA signal. The example vehicle system also includes a vehicle. The vehicle includes an LF module to transmit the beacon at a predefined interval, a receiver-transceiver module to receive the return signal and the RePA signal, a controller to enable RePA responsive to determining that the distance indicator is less than a tethering threshold distance, and an autonomy unit to perform RePA based on the RePA signal.

Abstract: A computer-implemented method, system or product, the method comprising receiving, by a memory management system, a first memory request from a first thread in a multi-threaded computing environment, the memory request including a target value associated with a size of memory requested by the first thread; in response to receiving the first memory request, retrieving a header referencing a first node in a linked list data structure having a plurality of connected nodes, the header comprising a first pointer value, referring to a free first memory block, and a first size value associated with a size of the first memory block; reading, by way of an atomic operation, the first pointer value and the first size value from the linked list data structure.

Abstract: A computing system and method for classifying a reliability distribution model for a part derived from empirical reliability data for the part includes a module for converting the reliability distribution model and the empirical reliability data into a plurality of data points in a matrix. The matrix is inputted to a machine-learned pattern recognition algorithm trained to assign the matrix to one of a predetermined plurality of classes. The machine-learned algorithm assigns the matrix to one of a predetermined plurality of classes according to an assessment, by the machine-learned pattern recognition algorithm, of the statistical fit between the reliability distribution model and the empirical reliability data on which the reliability distribution model was based.

Abstract: Disclosed herein is a method and system for CO2 removal from a gas stream using a diamine solvent having a Formula I R1(R2)N-L1-NH-R3 ??(I) With respect to Formula I, each of R1 and R2 independently is aliphatic, cycloaliphatic, or R1 and R2 together with the nitrogen to which they are attached, form a heterocyclyl ring; L1 is aliphatic, cycloaliphatic, or L1 and R1 together with the nitrogen to which they are attached form a heterocyclyl ring; and R3 is aliphatic, cycloaliphatic, cycloalkylalkyl, or alkoxyalkyl. And/or the compound may have a viscosity of less than 75 cP at a CO2-loading of 40 mol % and at a temperature of 40° C.

Abstract: Described are assay methods, modules and kits useful in the detection, treatment and/or prevention of dementia and related conditions, including but not limited to Alzheimer's disease and mild cognitive disorders.