Abstract: The present invention provides novel attenuated Pasteurella multocida strains that may be used, in live or killed form, to formulate vaccines that are highly protective against P. multocida infection in bovines, other mammals, and in birds. The present invention also identifies the combination of nanP and hyaC gene mutations as key to the provision of such vaccines. When appropriately formulated, antigenic material of numerous other bovine pathogens may be combined with the live attenuated Pasteurella multocida strains, to make effective combination vaccines.

Abstract: Shielding techniques are used to provide an embedded sensor element such as a temperature sensing element on a wide bandgap power semiconductor device. A semiconductor device may include a drift layer and an embedded sensor element. The drift layer may be a wide bandgap semiconductor material. A shielding structure is provided in the drift layer below the embedded sensor element. The embedded sensor element may be provided between contacts that are in electrical contact with the shielding well. The distance between the contacts may be minimized. A noise reduction well may be provided between the contacts to further isolate the embedded sensor element from parasitic signals.

Abstract: The disclosure provides apparatus and methods of use pertaining to a bidirectional biomechanical prosthetic finger assembly. One embodiment includes a metacarpophalangeal (MCP) pivot configured for swivelable attachment to a hand of a user, a distal coupler, and an articulation assembly rotatively coupled therebetween. A multiple-finger ring configured to receive a user's residual finger and at least one adjacent finger is disposed upon the articulation assembly, and may be adjusted to a target location based on a length of the residual finger. The articulation assembly is configured to utilize vertical movements of the residual and/or adjacent finger(s) within the multiple-finger ring to articulate the distal coupler within a plane parallel to an x-z plane, and the MCP pivot is configured to utilize lateral movements of the residual finger within the ring to articulate the distal coupler within a plane parallel to an x-y plane. Other embodiments are also disclosed.

Abstract: A sieving device is described. The sieving device includes an adjustable sieve surface that includes a first sieve surface and a second sieve surface. Openings are formed in each of the first sieve surface and the second sieve surface so as to define a shared pathways extending through the adjustable sieve surface. The shared pathways are defined by a length dimension that is greater than a width dimension. The width dimension can correspond to a cephalothorax width of an insect.

Abstract: The present disclosure provides compounds of Formula (I?), Formula (II), and Formula (III). The compounds described herein may useful in treating and/or preventing protozoan infections in a subject in need thereof, treating and/or preventing trypanosomal infections (e.g., Trypanosoma cruzi (T. cruzi) or Trypanosoma brucei infections) and/or plasmodial infections in a subject in need thereof, treating and/or preventing diseases in a subject in need thereof (e.g., Chagas disease, malaria, and/or sleeping sickness), and may be useful in treating and/or preventing infectious diseases in a subject in need thereof. Also provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including a compound described herein.

Abstract: An apparatus or method implemented in a computer system. In one embodiment the method includes receiving, from a device, a request to join a video call, and determining, in response to receiving the request, whether the device meets predetermined requirements to join the video call via videoconferencing. The method further includes sending, in response to determining the device does not meet the predetermined requirements to join the video call via videoconferencing, a message to the device, wherein the message comprises a link to join the call via audio conferencing.

Abstract: A method and apparatus for reclaiming refrigerant. The method includes transferring, an unreclaimed refrigerant composition, including one or more hydrofluoro olefins, from a source vessel to a receiving vessel and transporting the receiving vessel to a recycling center. The unreclaimed refrigerant composition is analyzed to determine the composition of the unreclaimed refrigerant composition sample. A target composition is determined, based on the analyzed unreclaimed refrigerant composition, and one or more treatments are determined, based on the target composition. The unreclaimed refrigerant composition is treated, with the one or more treatments, to form a reclaimed refrigerant composition having the composition of the reclaimed refrigerant composition is equal to the target composition.

Abstract: A locking mechanism can be used for securing a scooter or other vehicle. The locking mechanism can secure a wheel of the scooter in a left or right steering position. The locking mechanism can be manually actuated by the user, such as by a foot or hand of the user. Once the wheel is secured in place, the scooter may be difficult to ride without unlocking. The locking mechanism can be unlocked through a wireless connection with a remote control (e.g. a phone).

Abstract: An axial seal assembly is for sealing against a radial engagement surface of an outer member or an inner member disposed within a bore of the outer member. The seal assembly includes an annular case coupled with the outer member or disposed about the inner member and an annular elastomeric seal body. The seal body includes an inner portion attached to the case and an outer portion extending axially and radially from the inner portion so as to be positionable generally parallel to the radial engagement surface. The outer portion has a contact section extending generally axially from a remainder of the outer portion and being sealingly engageable with the radial engagement surface, the seal body outer portion being bendable about the seal body inner portion such that the seal body outer portion remains parallel to the engagement surface during axial displacement between the annular case and the engagement surface.

Abstract: The present disclosure is concerned with fertilizer compositions that provide controlled, delayed, and/or prolonged release of micronutrients in soil. In one embodiment, the inventive composition comprises a dry, powdered blend of a first target micronutrient source in chelated form and a second source of the same target micronutrient but provided in non-chelated form. In another embodiment, the inventive composition provides at least two sources of boron, with one source being a water-soluble form and the other source being a water-insoluble form. Regardless of the embodiment, the methods of using the fertilizer composition results in increased uptake of the particular micronutrient, nitrogen, and/or potassium compared to the prior art.

Abstract: A method for treating a tumor, comprising identifying a tumor as a pancreatic cancer tumor and implanting in the tumor identified as a pancreatic cancer tumor, at least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 5.6 Mega becquerel (MBq) hour and 11.6 MBq hour, per centimeter length.

Abstract: A horse puppet audio player device for celebrating a baseball home run includes a puppet configured for resembling a horse. The horse has a body. A head of the horse is positioned on a top surface of the body. An opening for a pocket is positioned on a bottom surface of the body. A plurality of legs is positioned on the bottom surface of the body and protrudes out therefrom. A plurality of hair is positioned on the horse and includes a tail and a head hair. The tail is positioned on an end of the body of the horse. The head hair is positioned on a path from the head to the body of the horse. A jersey is worn on the body of the horse. An audio player is positioned in a leg of the plurality of legs.

Abstract: In accordance with at least one aspect of this disclosure, a system includes, an environmental control system (ECS) having a plurality of ducts configured to convey a flow of air into an interior space through the plurality of ducts, a plurality of valves disposed in the plurality of ducts to control the flow of air through a respective duct into the interior space, an overhead bin mounted in the interior space below the plurality of ducts relative to the direction of airflow, and a diffuser disposed at an outlet of the plurality of duct configured to induce the airflow to flow along a convex outer surface of the overhead bin.

Abstract: A transdermal drug delivery device is disclosed. Over an extended wear period, the device causes cumulative moderate irritation plus significant irritation of less than 5% and/or achieves a meaningful degree of detachment over a seven day period of less than 20%.

Abstract: Methods and devices described for improved catheters including those having a deflectable section to allow for expansion while maintaining flow through a vessel.

Abstract: In package intra-chip and/or inter-chip optical communications are provided using microLEDs and photodetectors mounted to integrated circuit (IC) chips and/or to transceiver dies associated with the IC chips. Light from the LEDs may pass through waveguides on or in a substrate to which the IC chips are mounted or which couple the IC chips.

Abstract: A computer-implemented method of using video program viewer interaction data that has been loaded to a media measurement database as input to a measurement engine which then calculates Linear, DVR, and VOD asset viewing activity at three levels: (a) Video Program, (b) Video Program Airing, (c) Video Program Airing Segment, where each level provides summary metrics for groupings of Demographic, Geographic, and/or Device Characteristic, and also second-by-second viewing metrics, including counting advertising impressions, within the Demographic, Geographic, Device groupings. System also accounts for reduced value of ad viewing when viewer is using trick plays or when viewer delays viewing recorded content. Together these metrics provide detailed information on customer viewing behavior which can be used to drive business decisions for service providers, advertisers and content producers. Additionally, a viewing histogram analysis is produced.

Abstract: Disclosed herein are novel compositions and methods for stimulation of and the production or expansion of natural killer (NK) cells. Numbers of NK cells can be increased following contact with exosomes modified with one or more stimulatory peptides. Methods and compositions for the production of exosomes, wherein the exosomes comprises stimulatory peptides are also described. Also described are methods of treating cancer using the disclosed NK-stimulating exosomes or NK cells stimulated by the disclosed methods.

Abstract: A magnetic rod guide for a filter is provided that includes a base for attachment to part of a filter, a through aperture through which a magnetic rod can move, and resilient engagement device. The resilient engagement device includes one or more resilient latches for holding the magnetic rod in one or more fixed positions relative to the guide. Each resilient latch is adapted to allow movement of the magnetic rod through the through aperture in either direction, for insertion into the flier or withdrawal from the filter into one of the fixed positions.