Patents by Inventor Robert Overell
Robert Overell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11707483Abstract: Provided herein are micellic assemblies comprising a plurality of copolymers. In certain instauces, micellic assemblies provided herein are pH sensitive particles.Type: GrantFiled: September 23, 2019Date of Patent: July 25, 2023Assignees: UNIVERSITY OF WASHINGTON, GENEVANT SCIENCES GMBHInventors: Patrick S. Stayton, Allan S. Hoffman, Anthony Convertine, Craig L. Duvall, Danielle Benoit, Robert Overell, Paul H. Johnson, Anna S. Gall, Mary G. Prieve, Amber E. E. Paschal, Charbel Diab, Priyadarsi De
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Publication number: 20200147121Abstract: Provided herein are micellic assemblies comprising a plurality of copolymers. In certain instances, micellic assemblies provided herein are pH sensitive particles.Type: ApplicationFiled: September 23, 2019Publication date: May 14, 2020Applicants: University of Washington, GENEVANT SCIENCES GMBHInventors: Patrick S. Stayton, Allan S. Hoffman, Anthony Convertine, Craig L. Duvall, Danielle Benoit, Robert Overell, Paul H. Johnson, Anna S. Gall, Mary G. Prieve, Amber E.E. Paschal, Charbel Diab, Priyadarsi De
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Patent number: 10420790Abstract: Provided herein are micellic assemblies comprising a plurality of copolymers. In certain instauces, micellic assemblies provided herein are pH sensitive particles.Type: GrantFiled: April 27, 2017Date of Patent: September 24, 2019Assignees: University of Washington, GENEVANT SCIENCES GMBHInventors: Patrick S. Stayton, Allan S. Hoffman, Anthony Convertine, Craig L. Duvall, Danielle Benoit, Robert Overell, Paul H. Johnson, Anna S. Gall, Mary G. Prieve, Amber E. E. Paschal, Charbel Diab, Priyadarsi De
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Publication number: 20170239360Abstract: Provided herein are micellic assemblies comprising a plurality of copolymers. In certain instauces, micellic assemblies provided herein are pH sensitive particles.Type: ApplicationFiled: April 27, 2017Publication date: August 24, 2017Applicants: University of Washington, PhaseRx, Inc.Inventors: Patrick S. Stayton, Allan S. Hoffman, Anthony Convertine, Craig L. Duvall, Danielle Benoit, Robert Overell, Paul H. Johnson, Anna S. Gall, Mary G. Prieve, Amber E.E. Paschal, Charbel Diab, Priyadarsi De
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Patent number: 9662403Abstract: Provided herein are micellic assemblies comprising a plurality of copolymers. In certain instances, micellic assemblies provided herein are pH sensitive particles.Type: GrantFiled: March 2, 2016Date of Patent: May 30, 2017Assignees: University of Washington, PhaseRx, Inc.Inventors: Patrick S. Stayton, Allan S. Hoffman, Anthony Convertine, Craig L. Duvall, Danielle Benoit, Robert Overell, Paul H. Johnson, Anna S. Gall, Mary G. Prieve, Amber E. E. Paschal, Charbel Diab, Priyadarsi De
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Publication number: 20160250338Abstract: Provided herein are micellic assemblies comprising a plurality of copolymers. In certain instances, micellic assemblies provided herein are pH sensitive particles.Type: ApplicationFiled: March 2, 2016Publication date: September 1, 2016Applicants: University of Washington, PhaseRx, Inc.Inventors: Patrick S. Stayton, Allan S. Hoffman, Anthony Convertine, Craig L. Duvall, Danielle Benoit, Robert Overell, Paul H. Johnson, Anna S. Gall, Mary G. Prieve, Amber E.E. Paschal, Charbel Diab, Priyadarsi De
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Publication number: 20160082121Abstract: A composition for delivering an agent to a cell, comprising a bispecific affinity reagent and a pH-responsive, membrane destabilizing polymer. The bispecific affinity reagent may include a first affinity reagent covalently linked to a second affinity reagent, wherein the first affinity reagent binds to a molecule on the surface of a cell, and the second affinity reagent binds to an intracellular target.Type: ApplicationFiled: December 2, 2015Publication date: March 24, 2016Applicants: University of Washington, PhaseRx, Inc.Inventors: Patrick S. Stayton, Allan S. Hoffman, Anthony Convertine, Craig L. Duvall, Robert Overell, Paul Johnson
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Patent number: 9220791Abstract: A composition for delivering an agent to a cell, comprising a bispecific affinity reagent and a pH-responsive, membrane destabilizing polymer. The bispecific affinity reagent may include a first affinity reagent covalently linked to a second affinity reagent, wherein the first affinity reagent binds to a molecule on the surface of a cell, and the second affinity reagent binds to an intracellular target.Type: GrantFiled: February 5, 2014Date of Patent: December 29, 2015Assignees: University of Washington, PhaseRx, Inc.Inventors: Patrick S. Stayton, Allan S. Hoffman, Anthony Convertine, Craig L. Duvall, Robert Overell, Paul Johnson
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Patent number: 9211250Abstract: Compositions comprising a heterogeneous polymeric micelle and an agent (e.g., a polynucleotide) associated with the micelle are disclosed, together with methods for intracellular delivery of such agent.Type: GrantFiled: May 13, 2009Date of Patent: December 15, 2015Assignees: University of Washington, PhaseRx, Inc.Inventors: Paul Johnson, Patrick S. Stayton, Allan S. Hoffman, Robert Overell, Anna Gall, Mary Prieve, Amber Paschal, Charbel Diab, Priyadarsi De
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Publication number: 20150238619Abstract: Provided herein are polymeric carriers suitable for the delivery of polynucleotides (e.g., oligonucleotides) and/or other therapeutic agents into a living cell.Type: ApplicationFiled: February 24, 2015Publication date: August 27, 2015Applicants: PHASERX, INC., UNIVERSITY OF WASHINGTONInventors: Patrick S. Stayton, Allan S. Hoffman, Anthony J. Convertine, Craig L. Duvall, Danielle Benoit, Robert Overell, Paul H. Johnson, Anna S. Gall, Mary G. Prieve, Amber E.E. Paschal, Charbel Diab, Priyadarsi De
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Publication number: 20140228516Abstract: A composition for delivering an agent to a cell, comprising a bispecific affinity reagent and a pH-responsive, membrane destabilizing polymer. The bispecific affinity reagent may include a first affinity reagent covalently linked to a second affinity reagent, wherein the first affinity reagent binds to a molecule on the surface of a cell, and the second affinity reagent binds to an intracellular target.Type: ApplicationFiled: February 5, 2014Publication date: August 14, 2014Applicants: PHASERX, INC., UNIVERSITY OF WASHINGTONInventors: Patrick S. Stayton, Allan S. Hoffman, Anthony Convertine, Craig L. Duvall, Robert Overell, Paul Johnson
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Publication number: 20120021514Abstract: Compositions comprising a heterogeneous polymeric micelle and an agent (e.g., a polynucleotide) associated with the micelle are disclosed, together with methods for intracellular delivery of such agent.Type: ApplicationFiled: May 13, 2009Publication date: January 26, 2012Applicants: PHASERX, INC., UNIVERSITY OF WASHINGTONInventors: Paul Johnson, Patrick S. Stayton, Allan S. Hoffman, Robert Overell, Anna Gall, Mary Prieve, Amber Paschal, Charbel Diab, Priyadarsi De
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Publication number: 20110281934Abstract: Provided herein are micelles comprising a plurality of copolymers. In certain instances, micelles provided herein are pH sensitive particles.Type: ApplicationFiled: May 13, 2009Publication date: November 17, 2011Applicants: PHASERX, INC., UNIVERSITY OF WASHINGTONInventors: Paul Johnson, Patrick S. Stayton, Allan S. Hoffman, Robert Overell, Anna Gall, Mary Prieve, Amber Paschal, Charbel Diab, Priyadarsi De
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Patent number: 5736387Abstract: The invention provides retroviral vectors which can be used for directing gene delivery to a specific sub-population of mammalian cells. The vectors comprise chimeric targeting proteins which specifically alter the host range of the vector. The chimeric targeting proteins contain a ligand moiety which is capable of binding to receptors present on target cells, and an uptake moiety which is capable of promoting entry of the vector into the target cell. The ligand moiety is derived from a cytokine that acts upon the target cells of interest, and the uptake moiety is derived from a retroviral envelope protein.Type: GrantFiled: June 1, 1994Date of Patent: April 7, 1998Assignee: Targeted Genetics CorporationInventors: Ralph W. Paul, Robert Overell
