Abstract: Various compositions, methods, and devices are provided that use fluorescent nanoparticles, which can function as markers, indicators, and light sources. The fluorescent nanoparticles can be formed from a fluorophore core surrounded by a biocompatible shell, such as a silica shell. In one embodiment, the fluorescent nanoparticles can be delivered to tissue to mark the tissue, enable identification and location of the tissue, and/or illuminate an area surrounding the tissue. In another embodiment, the fluorescent nanoparticles can be used on a device or implant to locate the device or implant in the body, indicate an orientation of the device or implant, and/or illuminate an area surrounding the device or implant. The fluorescent nanoparticles can also be used to provide a therapeutic effect.

Abstract: A system for examining an area of a patient's anatomy that comprises a probe capable of fluorescing, and a scanning beam assembly that scans the probe with a beam of excitation radiation and detects the probe's fluorescence. The scanning beam assembly including a radiation source capable of emitting one or more wavelengths of radiation that are capable of exciting the probe and causing the probe to fluoresce, a scanning device that directs the radiation onto a field-of-view to create a scan of the field-of-view, a detector to detect radiation returned from the field-of-view, and a controller to convert the detected radiation into a displayable fluorescence image.

Abstract: Various compositions, methods, and devices are provided that use fluorescent nanoparticles to function as markers, indicators, and/or light sources. In an exemplary embodiment, the fluorescent nanoparticles are biocompatible, and more preferably they can be formed from a fluorophore core surrounded by a biocompatible shell, such as a silica shell. In one aspect, the fluorescent nanoparticles can be delivered to tissue to mark the tissue, enable identification and location of the tissue, and/or illuminate an area surrounding the tissue.

Abstract: Various compositions, methods, and devices are provided that use fluorescent nanoparticles, which can function as markers, indicators, and light sources. The fluorescent nanoparticles can be formed from a fluorophore core surrounded by a biocompatible shell, such as a silica shell. In one embodiment, the fluorescent nanoparticles can be delivered to tissue to mark the tissue, enable identification and location of the tissue, and/or illuminate an area surrounding the tissue. In another embodiment, the fluorescent nanoparticles can be used on a device or implant to locate the device or implant in the body, indicate an orientation of the device or implant, and/or illuminate an area surrounding the device or implant. The fluorescent nanoparticles can also be used to provide a therapeutic effect.

Abstract: Methods and devices are provided for performing various procedures using interchangeable end effectors. In general, the methods and devices allow a surgeon to remotely and selectively attach various interchangeable surgical end effectors to a shaft located within a patient's body, thus allowing the surgeon to perform various procedures without the need to remove the shaft from the patient's body. In an exemplary embodiment, multiple end effectors can be introduced into a body cavity. The end effectors can be disassociated or separate from one another such that they float within the body cavity. A distal end of a shaft can be positioned within the body cavity and it can be used to selectively engage one of the end effectors. In particular, the device can be configured to allow each end effector to be remotely attached and detached from the distal end of the shaft.

Abstract: Disclosed is a minimally invasive surgical instrument that may be used in hand-assisted laparoscopic surgeries. The device is a multifunctional surgical instrument that may be mounted directly on a surgeon's fingertip and inserted through an incision to allow the surgeon to manipulate tissue during a surgical procedure. Versions show a self-righting suture needle holder and a version with a dual pivoting jaw (e.g., grasper, cutter) that has an elongate neck to enhance the reach of the instrument. In addition, an elongate neck of an actuated fingertip instrument enhances the range reachable through a single incision.

Abstract: A first extruded member in joined to a molded member to form an integrated component. In one exemplary form, a surgical anchor is overmolded onto the end of an extruded suture to form a suture/anchor system.

Abstract: A method and devices for accomplishing the successful anastomosis of two hollow organ structures are disclosed. The method includes bringing the structures together, applying at least one fastener to hold the structures together and form a connection site, and applying, as alternatives or in conjunction, an adhesive, a wrap and/or a buttress about the connection site. Various examples of fasteners, fastener appliers, adhesives, adhesive initiators and buttress rings also are disclosed.

Abstract: A first apparatus for cleaning a distal end of a medical scope includes an annular sheath surroundingly attachable to the scope wherein the distal scope end is in fluid communication with the distal end of a lumen of the attached sheath with the proximal lumen end fluidly connectable to an irrigation fluid source and/or vacuum source. A second apparatus includes a motor-driven rotatable cannula having a closed distal end. A third apparatus includes an annular sheath and a lens which closes off the sheath, wherein the scope is insertable into the sheath, and wherein the lens is exposed to a distal lumen end of a lumen of the attached sheath. A fourth apparatus includes an annular sheath and a transparent shield rotatable attachable to the sheath to seal the distal sheath end. A fifth apparatus includes a sleeve attachable to and slidable along a scope.

Abstract: Disclosed is a minimally invasive surgical instrument that may be used in hand-assisted laparoscopic surgeries. The device is a multifunctional surgical instrument that may be mounted directly on a surgeon's fingertip and inserted through an incision to allow the surgeon to manipulate tissue during a surgical procedure. Versions include marking elements that are actuated to expose marking flowable fluid (e.g., ink pad, marker tip, roller ball). Versions include those that actuate to open an ampoule containing a flowable material (e.g., adhesive) with continued actuation causing dispensing. In addition, two compounds that are mixed at the time of application are provided with a bifurcated ampoule version and a dual cylinder/plunger version.

Abstract: The present invention provides a system for surgery which includes an ultrasonic hand piece having a end-effector, a console having a digital signal processor (DSP) for controlling the hand piece, and a memory disposed in the end-effector. The generator console sends a drive current to drive the hand piece which imparts ultrasonic longitudinal movement to the blade. As the generator console reads the memory, the hand piece is authenticated for use with the generator console if a copyrighted data string is present in the memory. In a particular embodiment, the data string is an encrypted code, where the hand piece is authenticated for use with the console by decoding a corresponding encryption algorithm resident in the generator console and providing a responding data pattern.

Abstract: According to the invention, a finger-operated switch for activating and operating an ultrasonic surgical handpiece is provided. The power output of the surgical handpiece is responsive and proportional to the pressure applied to the finger-operated switch.

Abstract: According to the invention, a finger-operated switch for activating and operating an ultrasonic surgical handpiece is provided. The power output of the surgical handpiece is responsive and proportional to the pressure applied to the finger-operated switch.

Abstract: Disclosed is a minimally invasive surgical instrument that may be used in hand-assisted laparoscopic surgeries. The device is an ultrasonic transmitter and receiver and may be mounted directed on a surgeon's fingertip and inserted through an incision to allow the surgeon to monitor the operational field during a surgical procedure. The device may be used in combination with tactile feedback or other means of alerting the surgeon of the presence of blood vessels or arteries, for example, to provide the surgeon with an improved tactile sense of the surgical field.

Abstract: Disclosed is a minimally invasive surgical instrument that may be used in hand-assisted laparoscopic surgeries. The device is multifunctional surgical instrument that may be mounted directly on a surgeon's fingertip and inserted through an incision to allow the surgeon to manipulate tissue during a surgical procedure. The surgical instrument may be used for blunt dissection and allows for finger actuation of two opposing jaws to enable the surgeon to grasp and dissect tissue.

Abstract: Disclosed is a minimally invasive surgical instrument that may be used in hand-assisted laparoscopic surgeries. The device is multifunctional surgical instrument that may be mounted directly on a surgeon's fingertip and inserted through an incision to allow the surgeon to manipulate tissue during a surgical procedure.

Abstract: The present invention provides a surgical handpiece having a switch end cap detachably and rotatably connected to the handpiece body. A surgical instrument is inserted within the handpiece body so that a portion thereof extends beyond the handpiece body and is actuated to perform a surgical operation. The switch end cap includes a switch mechanism having one or more switch button members for selectively signaling the level of power to be delivered to the handpiece from a power source. According to one aspect of the present invention, the switch mechanism within the switch end cap is electrically connected to the handpiece body in such a manner that permits the switch end cap to be freely rotated about the handpiece body, while still maintaining the electrical connection therebetween. This is accomplished by having conductive finger members and complementary conductive members provide the electrical connection between the switch end cap and the handpiece body.

Abstract: Methods of controlling fluid flow (e.g., flow of liquids, water vapor and gases) through switch members, e.g., switch buttons, which are used to seal an interior cavity of a surgical handpiece are provided. The switch members provide improved sealing properties which prevent gas and water vapor transmission across the switch member and into and out of the sealed internal switch chamber. The switch members are also resistant to puncture due to striking by tools or cleaning instruments, or the like.

Abstract: The present invention provides a system for surgery which includes an ultrasonic hand piece having a end-effector, a console having a digital signal processor (DSP) for controlling the hand piece, and a memory disposed in the end-effector. The generator console sends a drive current to drive the hand piece which imparts ultrasonic longitudinal movement to the blade. As the generator console reads the memory, the hand piece is authenticated for use with the generator console if a copyrighted data string is present in the memory. In a particular embodiment, the data string is an encrypted code, where the hand piece is authenticated for use with the console by decoding a corresponding encryption algorithm resident in the generator console and providing a responding data pattern.

Abstract: Methods of controlling fluid flow (e.g., flow of liquids, water vapor and gases) through switch members, e.g., switch buttons, which are used to seal an interior cavity of a surgical handpiece are provided. The switch members provide improved sealing properties which prevent gas and water vapor transmission across the switch member and into and out of the sealed internal switch chamber. The switch members are also resistant to puncture due to striking by tools or cleaning instruments, or the like.