Patents by Inventor Robert P. Hausinger

Robert P. Hausinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutant urease and method of use for determination of urea
    Patent number: 5846752
    Abstract: A mutant urease of Klebsiella aerogenes characterized as .alpha.H219Q having a glutamine (Q) in position 219 in place of histidine (H). The resulting enzyme has a low affinity for substrate (high value of K.sub.m) and is particularly useful in assays and test kits for measuring urea concentrations in body fluids.
    Type: Grant
    Filed: July 26, 1996
    Date of Patent: December 8, 1998
    Assignee: Board of Trustees operating Michigan State University
    Inventor: Robert P. Hausinger
  • Nucleic acids encoding mutant urease
    Patent number: 5783436
    Abstract: A mutant urease of Klebsiella aerogenes characterized as .alpha.H219 having a glutamine (Q) in position 219 in place of histidine (H). The resulting enzyme has a low affinity for substrate (high value of K.sub.m) and is particularly useful in assays and test kits for measuring urea concentrations in body fluids.
    Type: Grant
    Filed: November 11, 1997
    Date of Patent: July 21, 1998
    Assignee: Board of Trustees operating Michigan State University
    Inventor: Robert P. Hausinger