Abstract: An integrated electronic medical records and health care management system includes a managing application for receiving and storing member data associated with at least one member of a health plan. A risk assessment application coupled to the managing application generates a level of care for the member based upon the member data. A member safety knowledge database stores medication interaction data, and a clinical protocols knowledge database stores treatment data relating to the treatment of a plurality of health-related conditions. The managing application generates a plan of care for the member based upon the member data and member's level of care, the medication interaction data, and the treatment data. The managing application also monitors implementation of the member's plan of care and updates the plan of care based upon the implementation of the member's plan of care.