Abstract: Disclosed are methods of using inhibitors of tyrosine and threonine-specific cdc2-inhibitory kinase (Myt1), e.g., in the treatment of subjects in need thereof.

Abstract: Disclosed are compounds and pharmaceutically acceptable salts thereof that may be used in the treatment of subjects in need thereof. The compounds disclosed herein may be inhibitors of tyrosine and threonine-specific cdc2-inhibitory kinase (Myt1). Also disclosed are pharmaceutical compositions containing the compounds or pharmaceutically acceptable salts thereof and methods of their preparation and use.

Abstract: Disclosed are compounds and pharmaceutically acceptable salts thereof that may be used in the treatment of subjects in need thereof. The compounds disclosed herein may be inhibitors of tyrosine and threonine-specific cdc2-inhibitory kinase (Myt1). Also disclosed are pharmaceutical compositions containing the compounds or pharmaceutically acceptable salts thereof and methods of their preparation and use.

Abstract: System has an optical sensor (1), an aperture with the optical element (2) with the changeable permeability and an activation light (3) emitting radiation, which is detected by the optical sensor (1). The activation light is connected with the switch (4) and it is placed within the reach of the optical sensor (1). Within a device which realizes the technological process with the luminous manifestation the instruction for the beginning of a given technological process is detected and on the basis of this instruction the activation light (3) lights up. This activates the optical sensor (1) by means of the activation light (3) before the optical sensor (1) detects the luminous manifestation of the technological process itself. The activation light (3) can be a simple infrared LED diode.

Abstract: Technologies for maintaining integrity of requested data include data communicator circuitry and data integrity manager circuitry. The data communicator circuitry is configured to communicate a memory access request from a processor of the compute device to a memory of the compute device, obtain data associated with the memory access request from a data source via a communication channel, and obtain error control data associated with the data from the data source via an available communication channel that is different from the communication channel, wherein the data source is configured to provide requested data associated with the memory access request. The data integrity manager circuitry is configured to determine an integrity of the obtained data from the data source. In response to a determination that the obtained data includes an error, the data integrity manager is configured to correct the obtained data to generate corrected data.

Abstract: System has an optical sensor (1), an aperture with the optical element (2) with the changeable permeability and an activation light (3) emitting radiation, which is detected by the optical sensor (1). The activation light is connected with the switch (4) and it is placed within the reach of the optical sensor (1). Within a device which realizes the technological process with the luminous manifestation the instruction for the beginning of a given technological process is detected and on the basis of this instruction the activation light (3) lights up. This activates the optical sensor (1) by means of the activation light (3) before the optical sensor (1) detects the luminous manifestation of the technological process itself. The activation light (3) can be a simple infrared LED diode.

Abstract: The present invention relates more specifically to a bed sheet for secure placement of a child which provides breathable elements and/or a truss for preventing the child from being crushed or suffocated when a parent occupies a bed with the child. The bed sheet comprises at least one bumper extending upwardly from the top surface of the sheet. The bumpers form a substantially continuous closed wall that defines a secure area for the child to be placed. In one aspect of the invention, the bumper has an air flow passage that prevents suffocation of the child if the child's mouth and nose are forced against the bumper. In another aspect of the invention, a truss is disposed across and above at least a portion of the secure area when inserted into the bumpers.

Abstract: The invention relates to a flexible insert tube (1) for the lining of pipelines (2) and of ducts, in particular of sewers (4), where the flexible insert tube (1) has at least two sublayers (8, 10, 22), of which at least one first sublayer (8, 12) has fibres composed of an inorganic material and can be impregnated by a hardenable reactive composition, characterized in that in the direction from the inside to the outside, based on a longitudinal axis (6) of the flexible insert tube (1), a first inner sublayer (8) is followed by a further sublayer (10), which can be impregnated by the hardenable reactive composition, and whose proportion of fibres composed of an inorganic material is less than 100%.