Patents by Inventor Robert Patrick Doyle

Robert Patrick Doyle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conjugate of insulin and vitamin B12 for oral delivery
    Patent number: 8883723
    Abstract: Compositions containing a therapeutic peptide covalently linked to Vitamin B12 at the 5?-hydroxyl group of the ribose moiety of ?-ligand are described. The length of the linkage is optimized so that the biological activity of both the Vitamin B12 and the therapeutic peptide is maintained. Therapeutic peptide includes insulin, PYY, NPY and GLP-1. Attachment to Vitamin B12 provides uptake of the therapeutic peptide from the digestive tract and longer residence time.
    Type: Grant
    Filed: March 4, 2008
    Date of Patent: November 11, 2014
    Assignee: Syracuse University
    Inventor: Robert Patrick Doyle
  • Dynamic screentip language translation
    Patent number: 8612893
    Abstract: When a user interface cursor hovers over a user interface item, a determination is made as to whether the user interface item has an associated screentip. If the user interface item has an associated screentip, text associated with the screentip is identified, a translated text string is located for the text string, and the translated text string is displayed in the screentip. If the user interface item does not have an associated screentip, a determination is made as to whether the user interface item contains a text string. If so, a determination is made as to whether a translated text string is available that corresponds to the text in the user interface item. If so, the translated text string is displayed in a screentip for the user interface item.
    Type: Grant
    Filed: November 12, 2012
    Date of Patent: December 17, 2013
    Assignee: Microsoft Corporation
    Inventors: Colin Fitzpatrick, John Patrick Whelan, Robert Patrick Doyle, John Gerard Lane, Barry McHugh, Terry Farrell, Paul Barnes, Andre Michael McQuaid, David Mowatt
  • Dynamic screentip language translation
    Patent number: 8312390
    Abstract: When a user interface cursor hovers over a user interface item, a determination is made as to whether the user interface item has an associated screentip. If the user interface item has an associated screentip, text associated with the screentip is identified, a translated text string is located for the text string, and the translated text string is displayed in the screentip. If the user interface item does not have an associated screentip, a determination is made as to whether the user interface item contains a text string. If so, a determination is made as to whether a translated text string is available that corresponds to the text in the user interface item. If so, the translated text string is displayed in a screentip for the user interface item.
    Type: Grant
    Filed: June 10, 2009
    Date of Patent: November 13, 2012
    Assignee: Microsoft Corporation
    Inventors: Colin Fitzpatrick, John Patrick Whelan, Robert Patrick Doyle, John Gerard Lane, Barry McHugh, Terry Farrell, Paul Barnes, Andre Michael McQuaid, David Mowatt
  • Vitamine B12 - Peptide Conjugates for Oral Delivery
    Publication number: 20110092416
    Abstract: Compositions containing a therapeutic peptide covalently linked to Vitamin B12 at the 5?-hydroxyl group of the ribose moiety of ?-ligand are described. The length of the linkage is optimized so that the biological activity of both the Vitamin B12 and the therapeutic peptide is maintained. Therapeutic peptides for conjugation with vitamin B12 include insulin, PYY, NPY and GLP-1. Attachment to Vitamin B12 provides uptake of the therapeutic peptide from the digestive tract and longer residence time.
    Type: Application
    Filed: June 18, 2010
    Publication date: April 21, 2011
    Inventors: Robert Patrick DOYLE, Timothy J. FAIRCHILD
  • Oral delivery of tetanus toxoid
    Publication number: 20100330161
    Abstract: Orally active vitamin B12-tetanus toxoid (TT) conjugates are described. Attachment of TT to vitamin B12 provides for uptake of the conjugate from the digestive tract, and allows for delivery of the immunologically active TT to the blood. Pharmaceutical compositions and methods of disease prevention employing the orally active Vitamin B12-TT conjugate of the invention are also described.
    Type: Application
    Filed: June 29, 2010
    Publication date: December 30, 2010
    Applicant: SYRACUSE UNIVERSITY TECHNOLOGY TRANSFER AND INDUSTRIAL DEVELOPMENT OFFICE
    Inventors: Robert Patrick Doyle, Anthony Vortherms
  • DYNAMIC SCREENTIP LANGUAGE TRANSLATION
    Publication number: 20100318743
    Abstract: When a user interface cursor hovers over a user interface item, a determination is made as to whether the user interface item has an associated screentip. If the user interface item has an associated screentip, text associated with the screentip is identified, a translated text string is located for the text string, and the translated text string is displayed in the screentip. If the user interface item does not have an associated screentip, a determination is made as to whether the user interface item contains a text string. If so, a determination is made as to whether a translated text string is available that corresponds to the text in the user interface item. If so, the translated text string is displayed in a screentip for the user interface item.
    Type: Application
    Filed: June 10, 2009
    Publication date: December 16, 2010
    Applicant: Microsoft Corporation
    Inventors: Colin Fitzpatrick, John Patrick Whelan, Robert Patrick Doyle, John Gerard Lane, Barry McHugh, Terry Farrell, Paul Barnes, Andre Michael McQuaid, David Mowatt
  • Conjugate of insulin and vitamin B12 for oral delivery
    Publication number: 20080242595
    Abstract: Compositions containing a therapeutic peptide covalently linked to Vitamin B12 at the 5?-hydroxyl group of the ribose moiety of ?-ligand are described. The length of the linkage is optimized so that the biological activity of both the Vitamin B12 and the therapeutic peptide is maintained. Therapeutic peptide includes insulin, PYY, NPY and GLP-1. Attachment to Vitamin B12 provides uptake of the therapeutic peptide from the digestive tract and longer residence time.
    Type: Application
    Filed: March 4, 2008
    Publication date: October 2, 2008
    Applicant: Syracuse University
    Inventor: Robert Patrick Doyle