Abstract: The present disclosure is generally directed to the use of compositions that include antibodies, e.g., monoclonal, chimeric, affinity-matured, humanized antibodies, antibody fragments, etc., that specifically bind one or more epitopes within a Sortilin protein, e.g., human Sortilin or mammalian Sortilin, and have improved and/or enhanced functional characteristics, in treating and/or delaying progression of a disease or injury in an individual in need thereof.

Abstract: The present disclosure relates generally to biomarkers of activity and/or therapeutic efficacy of anti-CD33 antibodies for the treatment of a disease or injury in an individual, as well as methods related thereto.

Abstract: The present disclosure describes a device including a wall protruding from and surrounding a base portion and an open top portion located opposite the base portion. The device may define a volume corresponding to a predetermined macronutrient quantity for a food type. Also described is a kit including a first bowl and a second bowl. In some examples, the first and second bowls each include a wall protruding from and surrounding a base portion and defining an open top portion located opposite the base portion. According to some examples, the first bowl defines a first volume corresponding to a predetermined macronutrient quantity of a first food type and the second bowl defines a second volume corresponding to a predetermined macronutrient quantity of a second food type that is different from the first volume corresponding to the predetermined macronutrient quantity of the first food type.

Abstract: The present disclosure describes a device including a wall protruding from and surrounding a base portion and an open top portion located opposite the base portion. The device may define a volume corresponding to a predetermined macronutrient quantity for a food type. Also described is a kit including a first bowl and a second bowl. In some examples, the first and second bowls each include a wall protruding from and surrounding a base portion and defining an open top portion located opposite the base portion. According to some examples, the first bowl defines a first volume corresponding to a predetermined macronutrient quantity of a first food type and the second bowl defines a second volume corresponding to a predetermined macronutrient quantity of a second food type that is different from the first volume corresponding to the predetermined macronutrient quantity of the first food type.

Abstract: The present disclosure describes a device including a wall protruding from and surrounding a base portion and an open top portion located opposite the base portion. The device may define a volume corresponding to a predetermined macronutrient quantity for a food type. Also described is a kit including a first bowl and a second bowl. In some examples, the first and second bowls each include a wall protruding from and surrounding a base portion and defining an open top portion located opposite the base portion. According to some examples, the first bowl defines a first volume corresponding to a predetermined macronutrient quantity of a first food type and the second bowl defines a second volume corresponding to a predetermined macronutrient quantity of a second food type that is different from the first volume corresponding to the predetermined macronutrient quantity of the first food type.

Abstract: Certain aspects of the present disclosure provide techniques for a method of displaying a user interface on a mobile device, comprising: receiving a transaction file; performing text recognition on the transaction file to extract one or more transaction elements; determining a transaction characteristic based on the one or more transaction elements; displaying a transaction characteristic user interface element within an interactive cell displayed in the user interface; receiving a user touch gesture associated with the interactive cell via the user interface; and displaying an action user interface element in response to receiving the user touch gesture, wherein the action user interface element is configured to perform an action based on the transaction characteristic associated with the interactive cell.

Abstract: The present disclosure is generally directed to the use of compositions that include antibodies, e.g., monoclonal, chimeric, affinity-matured or humanized antibodies, antibody fragments, etc., that specifically bind one or more epitopes within a Sortilin protein, e.g., human Sortilin or mammalian Sortilin, and have improved and/or enhanced functional characteristics, in treating and/or delaying progression of a disease or injury in an individual in need thereof.

Abstract: The present disclosure is generally directed to the use of antibodies that specifically bind one or more epitopes within a sortilin protein, e.g., human sortilin or mammalian sortilin, for treating and/or delaying progression of a disease, disorder, or injury in an individual in need thereof.

Abstract: The present disclosure is generally directed to the use of compositions that include antibodies, e.g., monoclonal, chimeric, affinity-matured, humanized antibodies, antibody fragments, etc., that specifically bind one or more epitopes within a TREM2 protein, e.g., human TREM2, for use in treating and/or delaying progression of a disease or injury in an individual in need thereof.

Abstract: The present disclosure is generally directed to antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind one or more epitopes within a CD33 protein, e.g., human CD33 or a mammalian CD33, and have improved and/or enhanced functional characteristics. The present disclosure is further directed to the methods of treating and/or delaying the progression of a disease or injury in an individual by administering such antibodies.

Abstract: Certain aspects of the present disclosure provide techniques for a method of displaying a user interface on a mobile device, comprising: receiving a transaction file; performing text recognition on the transaction file to extract one or more transaction elements; determining a transaction characteristic based on the one or more transaction elements; displaying a transaction characteristic user interface element within an interactive cell displayed in the user interface; receiving a user touch gesture associated with the interactive cell via the user interface; and displaying an action user interface element in response to receiving the user touch gesture, wherein the action user interface element is configured to perform an action based on the transaction characteristic associated with the interactive cell.

Abstract: Methods of treating Alzheimer's Disease (AD) in patients suffering from mild to moderate AD, including ApoE4 positive patients and patients suffering from mild AD are provided.

Abstract: Methods of treating Alzheimer's Disease (AD) in patients suffering from mild to moderate AD, including ApoE4 positive patients and patients suffering from mild AD are provided.

Abstract: The present disclosure is generally directed to the use of compositions that include antibodies, e.g., monoclonal, chimeric, affinity-matured, humanized antibodies, antibody fragments, etc., that specifically bind one or more epitopes within a Sortilin protein, e.g., human Sortilin or mammalian Sortilin, and have improved and/or enhanced functional characteristics, in treating and/or delaying progression of a disease or injury in an individual in need thereof.

Abstract: An inherited dimension comprises one or more base dimension objects and one or more specialized dimension objects that are stored in a non-transitory volatile or non-volatile computer-readable storage. Each base dimension object of the one or more base dimension objects has a first set of dimension attributes that are common across the plurality of multidimensional datasets. The one or more specialized dimension objects include a specialized dimension object that has a second set of dimension attributes for a particular multidimensional dataset from the plurality of multidimensional datasets. In response to receiving a query that references the dimension and targets the particular multidimensional dataset, a base dimension object and the specialized dimension object are accessed to generate a query result.

Abstract: An apparatus for defining an acoustic reference for an audio system on an open air vehicle. The apparatus has a center frame module, a first side frame module extending laterally from a first side of the center frame and adjustable between 0 and 180 degrees with respect to the center frame, a second side frame module extending laterally from a second side of the center frame and adjustable between 0 and 180 degrees, and at least one piece of test equipment mounted to at least one of the center, first side or second side frames thereby defining the acoustic reference.

Abstract: Described is an approach for an improved method, system, and computer program product that performs zero-knowledge proof of knowledge of user identification and/or authentication for a decentralized, trustless storage and management of user identification and/or authentication using one or more distributed ledger systems.

Abstract: A torque shaft (20) comprising a hollow tube (22) provided with an end fitting (24, 26) at each end of a tube is made of a thermoplastic polymer matrix with reinforcing fibres embedded in the matrix, The tube (22) and end fittings (24, 26) are connected by mutually complementally shaped plugs (23) and sockets (27) that are dimensioned and positioned relative to each other to form an interference fit between the tube (22) and said plug (23) or socket (27).

Abstract: Techniques are described for inheritance of dimensional attributes in multidimensional datasets. In some embodiments, an inherited dimension comprises one or more base dimension objects and one or more specialized dimension objects that are stored in a non-transitory volatile or non-volatile computer-readable storage. Each base dimension object of the one or more base dimension objects has a first set of dimension attributes that are common across the plurality of multidimensional datasets. The one or more specialized dimension objects include a specialized dimension object that has a second set of dimension attributes for a particular multidimensional dataset from the plurality of multidimensional datasets. In response to receiving a query that references the dimension and targets the particular multidimensional dataset, a base dimension object and the specialized dimension object are accessed to generate a query result.

Abstract: Disclosed is a waterproofing membrane that comprises a carrier sheet (layer A); a waterproofing adhesive (layer B); a protective coating (layer C), wherein the protective coating is substantially free of surfactant and comprises an acrylic or methacrylic polymer or copolymer, an inorganic filler and a white pigment; and a releasable material (layer D), wherein the releasable material comprises amorphous nanoscale silica and a polymeric binder. The waterproofing membrane does not require a release liner, binds strongly to concrete cast against it (even after UV exposure), tolerates foot traffic, and withstands immersion in water over an extended period.