Abstract: The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose-cartridge and permit a user to set the delivery dose. The injector may include a housing, a piston rod adapted to operate through the housing, a dose dial sleeve located between the housing and the piston rod, and a drive sleeve located between the dose dial sleeve and the piston rod. The dose dial sleeve may have a helical thread of first lead and the drive sleeve may have a helical groove of second lead. The first lead of the helical thread and the second lead of the helical groove may be the same.

Abstract: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.

Abstract: A method of fractionating biomass, by permeability conditioning biomass suspended in a pH adjusted solution of at least one water-based polar solvent to form a conditioned biomass, intimately contacting the pH adjusted solution with at least one non-polar solvent, partitioning to obtain an non-polar solvent solution and a polar biomass solution, and recovering cell and cell derived products from the non-polar solvent solution and polar biomass solution. Products recovered from the above method. A method of operating a renewable and sustainable plant for growing and processing algae.

Abstract: An applicator unit for use in applying a substance to a surface, the applicator unit comprising: a body unit to which a container is movably disposed; an outlet unit which includes an applicator element to which substance is dispensed; and a pump unit which is operative to dispense substance to the applicator element on applying an actuation force to the container.

Abstract: A sensor kit comprising a sensor for detecting an analyte, a sensor housing and a calibration chamber. The calibration chamber comprises a first compartment containing a first calibration solution and a second compartment containing a source of the analyte to be detected. A dividing material is located between the first and second compartments enabling them to be mixed on breakage or removal of the dividing material. Further compartment(s) containing further source(s) of the analyte may optionally be provided. Calibration can carried out by (a) taking a reading of the analyte concentration of the first calibration solution, (b) mixing the contents of the first and second compartments by breaking or removing the dividing material, and (c) taking a reading of the analyte concentration of the resulting mixture. Steps (b) and (c) can be repeated for further compartment(s) to provide further reading(s) if desired.

Abstract: A method and system for proving a drug delivery device. The device comprises a drug delivery device housing and a medicament contained in the drug delivery device housing. A dose dial sleeve is positioned in the housing and is rotatable to set a non-inverted dose of the medicament contained in the medical delivery device. The non-inverted dose may be increased by turning the dose dial sleeve in a direction towards a user of the drug delivery device. The dose medicament may be decreased by rotating the dose dial sleeve in a direction away from the user.

Abstract: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.

Abstract: An applicator unit for use in applying a substance to a surface, the applicator unit comprising: a body unit to which a pressurizable container is in use attached; and an outlet unit which includes an applicator element to which substance is dispensed and a valve member which is movably disposed relative to the applicator element between a first, closed configuration in which the outlet unit is closed and a second, open configuration in which the outlet unit is opened such as to establish a communication path between the container and the applicator element, wherein the valve member is configured to be moved to the open configuration on pressurisation of the container, thereby providing for dispensing of substance to the applicator element.

Abstract: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.

Abstract: The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose-cartridge and permit a user to set the delivery dose. The injector may include a housing, a piston rod adapted to operate through the housing, a dose dial sleeve located between the housing and the piston rod, and a drive sleeve located between the dose dial sleeve and the piston rod. The dose dial sleeve may have a helical thread of first lead and the drive sleeve may have a helical groove of second lead. The first lead of the helical thread and the second lead of the helical groove may be the same.

Abstract: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve having a helical thread of a first lead, and a two-part piston rod. The two-part piston rod may include an outer part having a helical thread of a second lead and an inner part having a helical thread of a third lead. In such an embodiment, the first lead of the thread of the dose dial sleeve may be equal to the sum of the second lead of the thread of the outer part of the piston rod and the third lead of the thread of the inner part of the piston rod.

Abstract: A method for providing a gray water reclamation system includes connecting one or more gray water sources and one or more black water sources to a main drain line. A collection valve is also connected to the main drain line, the collection valve having (i) an inlet connected to the main drain line down stream from at least one of the black water sources, and (ii) an outlet connectable to either a gray water drain line or a black water drain line. A black water flow sensor is configured to detect water flow from a black water source, wherein the black water flow sensor is operable to transmit a black water event signal upon detecting water flow from the black water source, and wherein the collection valve is operable to connect the outlet to the black water drain line if the black water event signal is received thereby.

Abstract: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.

Abstract: The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose cartridge and permit a user to set the delivery dose. The injector may include a housing, a piston rod adapted to operate through the housing, a dose dial sleeve located between the housing and the piston rod, and a drive sleeve located between the dose dial sleeve and the piston rod. The dose dial sleeve may have a helical thread of first lead and the drive sleeve may have a helical groove of second lead. The first lead of the helical thread and the second lead of the helical groove may be the same.

Abstract: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve having a helical thread of a first lead, and a two-part piston rod. The two-part piston rod may include an outer part having a helical thread of a second lead and an inner part having a helical thread of a third lead. In such an embodiment, the first lead of the thread of the dose dial sleeve may be equal to the sum of the second lead of the thread of the outer part of the piston rod and the third lead of the thread of the inner part of the piston rod.

Abstract: A device for resisting rotation of a valve tappet, and in particular a roller valve tappet, is provided as part of a cylinder head gasket. The device includes a resilient portion having a flat face contacting a flat surface of a valve tappet to resist rotation thereof. The resiliency of the device urges the flat face against the flat surface of the valve tappet to resist rotation.