Patents by Inventor Robert Philip Hertzberg

Robert Philip Hertzberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IL-8 receptor antagonists
    Publication number: 20020128321
    Abstract: This invention relates to novel compounds and a novel use of phenyl ureas in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).
    Type: Application
    Filed: May 31, 2001
    Publication date: September 12, 2002
    Applicant: SmithKline Beecham Corporation
    Inventors: Katherine Louisa Widdowson, Daniel Frank Veber, Anthony Joseph Jurewicz, Robert Philip Hertzberg, Melvin Clarence Rutledge
  • IL-8 receptor antagonists
    Patent number: 6262113
    Abstract: The present invention relates to novel compounds and a novel use of phenyl ureas in the treatment of disease states mediated by the chemokine Interleukin-8 (IL-8).
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: July 17, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Katherine Louisa Widdowson, Daniel Frank Veber, Anthony Joseph Jurewicz, Robert Philip Hertzberg, Melvin Clarence Rutledge, Jr.
  • Phenyl urea antagonists of the IL-8 receptor
    Patent number: 6211373
    Abstract: This invention relates to novel compounds of Formula (I), and a novel use of these compounds in treating chemokine mediated diseases, wherein the chemokine binds to an IL-8 a or b receptor.
    Type: Grant
    Filed: July 8, 1998
    Date of Patent: April 3, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Katherine Louisa Widdowson, Daniel Frank Veber, Anthony Joseph Jurewicz, Robert Philip Hertzberg, Melvin Clarence Rutledge, Jr.
  • IL-8 receptor antagonists
    Patent number: 6180675
    Abstract: This invention relates to the novel use of phenyl ureas in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).
    Type: Grant
    Filed: January 29, 1999
    Date of Patent: January 30, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Katherine Louisa Widdowson, Daniel Frank Veber, Anthony Joseph Jurewicz, Robert Philip Hertzberg, Melvin Clarence Rutledge, Jr.
  • IL-8 receptor antagonists
    Patent number: 6005008
    Abstract: This invention relates to the novel use of phenyl ureas in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).
    Type: Grant
    Filed: August 15, 1997
    Date of Patent: December 21, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Katherine Louisa Widdowson, Daniel Frank Veber, Anthony Joseph Jurewicz, Robert Philip Hertzberg, Melvin Clarence Rutledge, Jr.
  • Substituted indolizino?1,2-b!quinolinones
    Patent number: 5883255
    Abstract: The present invention provides a method of treating viral infections by using antiviral substituted indolizino?1,2-b!quinolinone compounds, antiviral substituted indolizino?1,2-b!quinolinone compounds, and pharmaceutical compositions thereof.
    Type: Grant
    Filed: February 27, 1997
    Date of Patent: March 16, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: David Alan Berges, Robert Philip Hertzberg, Randall Keith Johnson, William Dennis Kingsbury
  • IL-8 receptor antagonists
    Patent number: 5780483
    Abstract: This invention relates to novel compounds and a novel use of phenyl ureas in the treatment of disease scates mediated by the chemokine, Interleukin-8 (IL-8). In particular, this invention relates to the novel compounds of Formula (Ia) and their use in treating chemokine mediated diseases wherein the chemokine binds to an IL-8 a or b receptor. Compounds of Formula (Ia) are represented by the structure: ##STR1## wherein interalia, X is oxygen or sulfur;Rb is NR.sub.6 R.sub.7, alkcyl, aryl, arylC.sub.1-4 alkyl, aryl C.sub.2-4 alkenyl, heteroaryl, heteroarylC.sub.1-4 alkyl, heteroarylC.sub.2-4 alkenyl, heterocyclic or heterocyclic C.sub.1-4 alkyl, or a heterocyclic C.sub.2-4 alkenyl moiety, camphor, all of which may be optionally substituted;R.sub.1 is independently selected from hydrogen; halogen; nitro; cyano; C.sub.1-10 alkyl; halosubstituted C.sub.1-10 alkyl; C.sub.2-10 alkoxy; halosubstituted C.sub.1-10 alkoxy; azide; (CR.sub.8 R.sub.8)q S(O).sub.t R.sub.4 ; hydroxy; hydroxy substituted C.sub.
    Type: Grant
    Filed: August 21, 1996
    Date of Patent: July 14, 1998
    Assignee: SmithKline Beecham Corporation
    Inventors: Katherine Louisa Widdowson, Daniel Frank Veber, Anthony Joseph Jurewicz, Robert Philip Hertzberg, Melvin Clarence Rutledge, Jr.
  • Coumarin derivatives as retroviral inhibitors
    Patent number: 5723631
    Abstract: The present invention relates to a process for the preparation of a compound of the following structure: ##STR1## wherein, substituents are as defined in the specification.
    Type: Grant
    Filed: June 22, 1995
    Date of Patent: March 3, 1998
    Assignee: SmithKline Beecham Corporation
    Inventors: Ashok Dharmaji Patil, Robert Philip Hertzberg, Geoffrey B. Dreyer, Alan James Freyer, John W. Westley, Balan Chenera, Michael Leo West