Abstract: Provided herein are methods of treating an autoantibody-mediated disease in a subject, methods of monitoring treatment of an autoantibody-mediated disease in a subject, based on the frequency of B cells in the subject.

Abstract: Injection-molding processes and systems are described herein. An exemplary method involves: (a) holding one or more inserts in a desired position within a mold cavity by contacting a retractable core to at least a portion of each insert, wherein the retractable core is a feature of a mold plate; (b) while the one or more inserts are being held in the desired position by the retractable core, initiating an injection of molten plastic into the mold cavity; (c) retracting the retractable core from the one or more inserts while continuing the injection of molten plastic into the mold cavity, wherein retracting the retractable core creates additional cavity space within the mold cavity between the retractable core and the one or more inserts; and (d) continuing the injection of molten plastic into the mold cavity until the mold cavity, including the additional cavity space, is filled.

Abstract: Injection-molding processes and systems are described herein. An exemplary method involves: (a) holding one or more inserts in a desired position within a mold cavity by contacting a retractable core to at least a portion of each insert, wherein the retractable core is a feature of a mold plate; (b) while the one or more inserts are being held in the desired position by the retractable core, initiating an injection of molten plastic into the mold cavity; (c) retracting the retractable core from the one or more inserts while continuing the injection of molten plastic into the mold cavity, wherein retracting the retractable core creates additional cavity space within the mold cavity between the retractable core and the one or more inserts; and (d) continuing the injection of molten plastic into the mold cavity until the mold cavity, including the additional cavity space, is filled.

Abstract: An assembly having an electric switching function, comprises a switch device which has associated electric conductors and a movable actuating part, on which a hood member is mounted, and which is provided in a housing comprised by an outer injection-molded body; the hood member has its rim resting on a first injection-molded synthetic material body that fixes and partially encloses the electric conductors, and is sealingly connected to the first injection-molded synthetic material body by means of the outer, second injection-molded synthetic material body that both covers the rim of the hood member and also adjoins the first injection-molded synthetic material body.

Abstract: For a conductor structure component with plastics material injection-molded therearound, a fixing member for electric conductors is inserted, which fixing member is formed by a prefabricated carrier body comprising receptacles for the retention of individual wires as said electric conductors.

Abstract: An assembly having an electric switching function, comprises a switch device which has associated electric conductors and a movable actuating part, on which a hood member is mounted, and which is provided in a housing comprised by an outer injection-molded body; the hood member has its rim resting on a first injection-molded synthetic material body that fixes and partially encloses the electric conductors, and is sealingly connected to the first injection-molded synthetic material body by means of the outer, second injection-molded synthetic material body that both covers the rim of the hood member and also adjoins the first injection-molded synthetic material body.

Abstract: A flanged ring for fixing a bearing in place at least axially with respect to a machine component is in the form of a ring-shaped sheet metal element provided with a break at least at one place on the circumference of the annular metal element. The break defines two adjacently positioned end regions of the annular metal element and these end regions are adapted to be permanently connected to one another by way of an interlocking connection. The interlocking connection can be constituted by a portion of one end region extending towards or being punched out towards the other end region. Alternatively, the interlocking connection can be provided by a connecting element (e.g., a rivet) that extends through a bore in each of the end regions.