Abstract: Systems, methods, and computer-readable media for exchanging medical research information are described. Medical research information may include information associated with a research project (for instance, a clinical trial) and/or the health or physical characteristics of a subject of the research project (“subject information”). In some embodiments, a medical research information exchange system (“exchange system”) may receive subject information from various information sources, such as a Health Information Exchange (HIE) or directly from a healthcare organization. The exchange system may process the subject information, for example, verifying that the subject information complies with protocols of the research project and transforming the subject information from a source format (for instance, Health Level-7 (HL7)) into a format that may be used by a research system (for instance, a Clinical Data Interchange Standards Consortium format (CDISC) format).