Patents by Inventor Robert R. Ryan

Robert R. Ryan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5702683
    Abstract: A family of contrast agents for use in magnetic resonance imaging and a method of enhancing the contrast of magnetic resonance images of an object by incorporating a contrast agent of this invention into the object prior to forming the images or during formation of the images. A contrast agent of this invention is a paramagnetic lanthanide hexaazamacrocyclic molecule, where a basic example has the formula LnC.sub.16 H.sub.14 N.sub.6. Important applications of the invention are in medical diagnosis, treatment, and research, where images of portions of a human body are formed by means of magnetic resonance techniques.
    Type: Grant
    Filed: January 22, 1991
    Date of Patent: December 30, 1997
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Paul H. Smith, James R. Brainard, Gordon D. Jarvinen, Robert R. Ryan
  • Patent number: 4923630
    Abstract: An organic extracting solution useful for separating elements of the actinide series of the periodic table from elements of the lanthanide series, where both are in trivalent form. The extracting solution consists of a primary ligand and a secondary ligand, preferably in an organic solvent. The primary ligand is a substituted monothio-1,3-dicarbonyl, which includes a substituted 4-acyl-2-pyrazolin-5-thione, such as 4-benzoyl-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-thione (BMPPT). The secondary ligand is a substituted phosphine oxide, such as trioctylphosphine oxide (TOPO).
    Type: Grant
    Filed: April 3, 1989
    Date of Patent: May 8, 1990
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Barbara F. Smith, Gordon D. Jarvinen, Robert R. Ryan
  • Patent number: 4867951
    Abstract: An organic extracting solution and an extraction method useful for separating elements of the actinide series of the periodic table from elements of the lanthanide series, where both are in trivalent form. The extracting solution consists of a primary ligand and a secondary ligand, preferably in an organic solvent. The primary ligand is a substituted monothio-1,3-dicarbonyl, which includes a substituted 4-acyl-2-pyrazolin-5-thione, such as 4-benzoyl-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-thione (BMPPT). The secondary ligand is a substituted phosphine oxide, such as trioctylphosphine oxide (TOPO).
    Type: Grant
    Filed: March 31, 1988
    Date of Patent: September 19, 1989
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Barbara F. Smith, Gordon D. Jarvinen, Robert R. Ryan