Patents by Inventor Robert R. Wolfe

Robert R. Wolfe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11273138
    Abstract: The present invention encompasses an amino acid composition for stimulating muscle protein synthesis. Further, the present disclosure relates generally to the use of an anabolic amino acid composition for the stimulation of muscle protein synthesis. In particular, disclosed are compositions and methods of using the same for the prevention and/or treatment of a loss of any one of muscle mass, muscle strength, muscle function, and physical function, or any combination thereof, in a mammal, especially an adult mammal. Also provided are kits comprising a composition for the stimulation of muscle protein synthesis and, in certain embodiments, instructions for administration.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: March 15, 2022
    Assignee: BioVentures, LLC
    Inventors: Robert R. Wolfe, Arny Ferrando
  • Publication number: 20200253908
    Abstract: The present invention encompasses an amino acid composition for stimulating muscle protein synthesis. Further, the present disclosure relates generally to the use of an anabolic amino acid composition for the stimulation of muscle protein synthesis. In particular, disclosed are compositions and methods of using the same for the prevention and/or treatment of a loss of any one of muscle mass, muscle strength, muscle function, and physical function, or any combination thereof, in a mammal, especially an adult mammal. Also provided are kits comprising a composition for the stimulation of muscle protein synthesis and, in certain embodiments, instructions for administration.
    Type: Application
    Filed: November 2, 2018
    Publication date: August 13, 2020
    Inventors: Robert R. Wolfe, Arny Ferrando
  • Patent number: 10022358
    Abstract: The present invention encompasses combinations comprising a plurality of amino acids, formulations thereof for use in humans and animals, as well as methods for increasing muscle protein synthesis, muscle strength, and/or muscle function in a subject with chronic heart failure, cardiac cachexia or a combination thereof.
    Type: Grant
    Filed: February 3, 2017
    Date of Patent: July 17, 2018
    Assignee: BioVentures, LLC
    Inventors: Robert R. Wolfe, Jeanne Wei
  • Publication number: 20170143679
    Abstract: The present invention encompasses combinations comprising a plurality of amino acids, formulations thereof for use in humans and animals, as well as methods for increasing muscle protein synthesis, muscle strength, and/or muscle function in a subject with chronic heart failure, cardiac cachexia or a combination thereof.
    Type: Application
    Filed: February 3, 2017
    Publication date: May 25, 2017
    Inventors: Robert R. Wolfe, Jeanne Wei
  • Patent number: 9597367
    Abstract: The present invention encompasses combinations comprising a plurality of amino acids, formulations thereof for use in humans and animals, as well as methods for increasing muscle protein synthesis, muscle strength, and/or muscle function in a subject with chronic heart failure, cardiac cachexia or a combination thereof.
    Type: Grant
    Filed: April 18, 2014
    Date of Patent: March 21, 2017
    Assignee: BIOVENTURES, LLC
    Inventors: Robert R. Wolfe, Jeanne Wei
  • Patent number: 9364463
    Abstract: The present invention encompasses an amino acid composition for recovery of muscle strength and function.
    Type: Grant
    Filed: November 19, 2012
    Date of Patent: June 14, 2016
    Assignee: BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS
    Inventors: Arny Ferrando, Robert R. Wolfe
  • Publication number: 20140343112
    Abstract: The present invention encompasses an amino acid composition for recovery of muscle strength and function.
    Type: Application
    Filed: November 19, 2012
    Publication date: November 20, 2014
    Inventors: Arny Ferrando, Robert R. Wolfe
  • Publication number: 20140315788
    Abstract: The present invention encompasses combination comprising a plurality of amino acids, formulations thereof for use in humans and animals, as well as methods for increasing muscle protein synthesis, muscle strength, and/or muscle function.
    Type: Application
    Filed: April 18, 2014
    Publication date: October 23, 2014
    Inventors: Robert R. Wolfe, Jeanne Wei
  • Patent number: 8703725
    Abstract: The present disclosure is directed to compositions for the promotion of muscle protein synthesis and control of tumor-induced weight loss in patients that are, for example, suffering from cancer cachexia. The present disclosure is also directed to methods of administering such compositions.
    Type: Grant
    Filed: November 28, 2012
    Date of Patent: April 22, 2014
    Assignee: Nestec S.A.
    Inventors: John P. Troup, Robert R. Wolfe
  • Publication number: 20120178672
    Abstract: A nutritional composition and method of use that improves the net balance in skeletal muscle by targeting both the synthetic and breakdown processes. The disclosed composition provides for improved protein intake to increase skeletal muscle protein accretion in stressed patients who are at risk for the development of renal insufficiency by stimulating protein synthesis.
    Type: Application
    Filed: March 18, 2010
    Publication date: July 12, 2012
    Inventors: Robert R. Wolfe, John P. Troup
  • Publication number: 20100267831
    Abstract: The present invention provides an amino acid-containing composition for preventing or remedying a decrease in skeletal muscle mass of aged people, comprising L-leucine at a molar composition ratio of 35% or more with respect to total of essential amino acids. According to the invention, the protein anabolism of skeletal muscle can be promoted to prevent or remedy a decrease of the skeletal muscle mass of aged people.
    Type: Application
    Filed: March 28, 2006
    Publication date: October 21, 2010
    Inventors: Hisamine Kobayashi, Hiromi Suzuki, Robert R. Wolfe, Christos S. Katsanos
  • Publication number: 20100179089
    Abstract: Compositions and methods for managing inflammation in the elderly by delivering a selection of amino acids, including arginine and/or citrulline, in a synergistic ratio with omega-3 fatty acids and carbohydrates with a low glycemic index.
    Type: Application
    Filed: January 13, 2009
    Publication date: July 15, 2010
    Inventors: Nicolaas E.P. Deutz, John P. Troup, Robert R. Wolfe
  • Publication number: 20090252684
    Abstract: Systems and methods by which optimal profiles of amino acids for specific tissues can be determined. The results of these systems and methods can then be sued to generate medical nutrition products targeting specific tissues either to enhance growth of specific tissues by providing complementary amino acids in a nutritional supplement or pharmaceutical composition form.
    Type: Application
    Filed: December 10, 2008
    Publication date: October 8, 2009
    Inventors: Robert R. Wolfe, John Troup, Nicolaas E. P. Deutz
  • Publication number: 20090203606
    Abstract: Nutritional compositions which provide for improved taste profiles for the elderly while simultaneously providing nutrition specific to assist in the management of nutritional deficiencies that lead to age specific and age associated health conditions in the elderly. There are also provided products using these compositions and incorporating packaging design, volume delivery, and sensory attributes to improve nutritional regimen compliance in the elderly.
    Type: Application
    Filed: February 5, 2009
    Publication date: August 13, 2009
    Inventors: Robert R. Wolfe, John P. Troup, Nicolaas E.P. Deutz
  • Publication number: 20080268038
    Abstract: Provided are compositions and methods for increasing diet induced thermogenesis. Typically, the compositions are comprised of L-histidine, L-isoleucine, L-leucine, L-lysine, L-methionine, L-phenylalanine, L-valine and L-threonine.
    Type: Application
    Filed: April 25, 2008
    Publication date: October 30, 2008
    Inventor: Robert R. Wolfe
  • Publication number: 20040087490
    Abstract: Compositions for the promotion of muscle protein synthesis and control of tumor-induced weight loss in patients that are, for example, suffering from cancer cachexia, and methods of administering such compositions.
    Type: Application
    Filed: September 15, 2003
    Publication date: May 6, 2004
    Inventors: John P. Troup, Robert R. Wolfe