Patents by Inventor Robert Redfield

Robert Redfield has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions for down-regulation of CCR5 expression and methods of use thereof
    Publication number: 20060154857
    Abstract: The present invention relates to the downregulation of surface receptor CCR5 expression through manipulation of the cell cycle in activated lymphocytes by administering a composition that arrests the G1 phase of the cell cycle, thereby reducing receptor sites for entry of HIV into T cells, and thus, the effects of HIV. Further, compositions are disclosed that include at least one G1 phase arresting agent and at least one antiviral agent, wherein the combination of agents synergistically enhances the activity of the antiviral agent.
    Type: Application
    Filed: November 16, 2005
    Publication date: July 13, 2006
    Applicant: University of Maryland Biotechnology Institute
    Inventors: Robert Redfield, Anthony Amoroso, Charles Davis, Alonso Heredia
  • Compositions for inducing increased levels of beta-chemokines and methods of use therefor
    Publication number: 20060099170
    Abstract: The present invention relates to compositions and methods for inducing increased levels and availability of ?-chemokines by administering to a subject at least one G1 phase arresting compound, wherein the increased levels and availability of ?-chemokines block chemokine/viral receptors thereby preventing or treating viral infections.
    Type: Application
    Filed: September 12, 2003
    Publication date: May 11, 2006
    Inventors: Robert Redfield, Anthony Amoroso, Charles Davis, Alonso Heredia
  • Synergistic combinations of guanosine analog reverse transcriptase inhibitors and inosine monophosphate dehydrogenese inhibitors and uses therefor
    Patent number: 6514979
    Abstract: Synergistic combinations of guanosine nucleoside analog reverse transcriptase inhibitors such as abacavir with inosine monophosphate dehydrogenase inhibitors such as mycophenolates, pharmaceutical compositions comprising such combinations, and therapeutic methods comprising administering the synergistic combinations to subjects in need thereof, for treating a viral infection, such as an HIV-1 infection.
    Type: Grant
    Filed: March 3, 1999
    Date of Patent: February 4, 2003
    Assignee: University of Maryland Biotechnology Institute
    Inventors: David Margolis, Alonso Heredia, David Oldach, Robert Redfield