Patents by Inventor Robert Rippel

Robert Rippel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted cyclohexane derivatives for the treatment of diseases
    Patent number: 5451573
    Abstract: Substituted cyclohexane derivatives for the treatment of diseases Esters of cyclohexane derivatives of the formula I ##STR1## in which A--B, R.sup.3, R.sup.4, R.sup.5, Y and Z have the meanings indicated, for use as inhibitors of the glucose-6-phosphatase system of the liver in mammals are described. The compounds are suitable for the production of pharmaceutical preparations.
    Type: Grant
    Filed: September 7, 1993
    Date of Patent: September 19, 1995
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Horst Hemmerle, Peter Schindler, Roland Utz, Robert Rippel, Andreas Herling
  • Process for the preparation of thiophene derivatives and also new dihydrothiophene 1-oxides
    Patent number: 5166346
    Abstract: Process for the preparation of thiophene derivatives and also new dihydrothiophene 1-oxides.Thiophene derivatives having an--optionally substituted--amino group on the thiophene ring are prepared by dehydrogenating dihydrothiophenes, substituted in a manner identical to that of the desired thiophene derivatives, by means of H.sub.2 O.sub.2, the dihydrothiophenes being reacted with H.sub.2 O.sub.2 in a first reaction stage in a neutral medium to give the corresponding sulfoxides, which are then rearranged into the thiophene derivatives by means of acid in the second reaction stage.The dihydrothiophene 1-oxides formed as intermediates in this reaction are new compounds. Like the thiophene derivatives formed from them by rearrangement with acid, they are intermediates, mainly in the sector of plant protection agents and pharmaceuticals.
    Type: Grant
    Filed: December 20, 1990
    Date of Patent: November 24, 1992
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Robert Rippel, Hans-Wolfram Flemming, Manfred Rukwied
  • Substituted thienoimidazole derivatives
    Patent number: 5114955
    Abstract: Substituted thienoimidzaole derivatives, processes for their preparation, pharmaceutical preparations containing them and their use as inhibitors of gastric acid secretion.The invention relates to substituted thienoimidazole derivatives of the formula ##STR1## in which A stands for ##STR2## T denotes --S--, --SO-- or --SO.sub.2 --, R.sup.7 denotes a substituted aryloxy or aralkoxy radical and R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.8 have the meanings indicated in the description, processes for their preparation, pharmaceutical preparations containing them and their use as medicaments.
    Type: Grant
    Filed: November 10, 1988
    Date of Patent: May 19, 1992
    Assignee: Hoechst Aketiengesellschaft
    Inventors: Hans-Jochen Lang, Klaus Weidmann, Karl-Heinz Scheunemann, Hildegard Nimmesgern, Robert Rippel, Andreas W. Herling
  • Substituted thienoimidazole derivatives, a process for the preparation thereof, pharmaceutical compositions containing them, and the use thereof as inhibitors of gastric acid secretion, as gastroprotectives and as medicaments for intestinal inflammations
    Patent number: 4956366
    Abstract: Substituted thienoimidazole derivatives, a process for the preparation thereof, pharmaceutical compositions containing them, and the use thereof as inhibitors of gastric acid secretion, as gastroprotectives and as medicaments for intestinal inflammationsThe invention relates to compounds of the formula ##STR1## in which A represents ##STR2## T denotes --S--, --SO-- or --SO.sub.2 --, R.sup.1 to R.sup.10, X, Y and Z have the meanings indicated in the description, to a process for the preparation thereof, to pharmaceutical compositions containing them, and to the use thereof as inhibitors of gastric acid secretion, as gastroprotectives and as medicaments for intestinal inflammations.
    Type: Grant
    Filed: July 13, 1988
    Date of Patent: September 11, 1990
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hildegard Nimmesgern, Klaus Weidmann, Hans-Jochen Lang, Robert Rippel, Andreas W. Herling
  • Substituted thienoimidazole-toluidine derivatives as inhibitors of gastric acid secretion
    Patent number: 4871734
    Abstract: Thienoimidazole-toluidines of the formula I ##STR1## in which A represents ##STR2## T denotes --S--, --SO-- or --SO.sub.2 --, and R.sup.1 to R.sup.9 have the meanings stated in the description, and a process for their preparation, pharmaceutical compositions containing them, and their use as inhibitors of gastric acid secretion, are described.
    Type: Grant
    Filed: November 20, 1987
    Date of Patent: October 3, 1989
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Jochen Lang, Manfred Rosner, Weidmann, Klaus, Robert Rippel, Andreas W. Herling
  • Substituted thienoimidazole derivatives, pharmaceutical compositions containing them, and their use as inhibitors of gastric acid secretion
    Patent number: 4845118
    Abstract: The invention relates to compounds of the formula ##STR1## in which A represents ##STR2## T denotes --S--, --SO-- or --SO.sub.2 --, and R.sup.1 to R.sup.9 have the meanings given in the description, to a process for their preparation, to pharmaceutical compositions containing them, and to their use as inhibitors of gastric acid secretion.
    Type: Grant
    Filed: December 22, 1987
    Date of Patent: July 4, 1989
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Jochen Lang, Robert Rippel, Andreas W. Herling, Klaus Weidmann