Abstract: Methods and systems are described for providing deep brain stimulation (DBS) of the subcallosal cingulate region (SCC) to provide symptom relief in patients with treatment-resistant depression (TRD). The DBS devices may enable chronic electrophysiology recording to deliver SCC DBS therapy. One or more machine-learning models may identify SCC LFP changes that indicate the patient's current clinical state. The clinical state is distinct from acute transient stimulation effects, is sensitive to DBS stimulation adjustments, and accurately captures individual differences in recovery trajectory.

Abstract: An animal containment and transport assembly for transporting a pet includes a housing and a pair of covers. A top of the housing is open. The covers are hingedly engaged to the housing and are positioned to selectively close the top. The housing and the pair of covers thus define an interior space that can contain an animal. The covers are selectively engageable to the housing so that the covers are fixedly positioned over the top. A plurality of wheels is engaged to a bottom of the housing. A pull handle is engaged to and is selectively extensible from the housing. The pull handle can be grasped in a hand of a user, positioning the user to pull on the pull handle to locomote the housing across a surface.

Abstract: A quoit throwing game including three posts impaled at each end of a quoit pitching area or range; the posts being arrayed in a row longitudinally of the range with the intermediate post highest, so that the intermediate post most easily receives thereover a thrown quoit, the forward post receiving thereover a thrown quoit with some difficulty, and the rearward post receiving thereover a thrown quoit with greatest difficulty.