Abstract: In one embodiment, a system includes at least one projector configured to project a plurality of projected patterns, where a projected lighting characteristic of each of the projected patterns varies over a time period in accordance with an associated predetermined temporal lighting-characteristic pattern, a camera configured to capture images of detected patterns during the time period, and one or more processors configured to: determine, for each detected pattern, a detected temporal lighting-characteristic pattern based on variations in a detected lighting characteristic of the detected pattern, identify a detected pattern that corresponds to one of the projected patterns by comparing at least one of the detected temporal lighting-characteristic patterns to at least one of the temporal lighting-characteristic patterns, and compute a depth associated with the detected patterns based on the one or more of the projected patterns, the detected pattern, and a relative position between the camera and the project

Abstract: The present ventilator system, for detecting and treating concurrent chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA event(s)) overlap syndrome, comprises a pressure generator for generating a pressurized flow of breathable gas for delivery to an airway of a subject; sensor(s) for generating output signals conveying information related to breathable gas parameters; and processor(s) operatively connected to the sensor(s) and the pressure generator, configured to: detect presence of OSA event(s) and/or expiratory flow limitation (EFL) in the subject based on the output signals.

Abstract: A system for determining an airway flow value in a patient is provided. The system comprises a computer system that comprises one or more physical processors programmed with computer program instructions which, when executed cause the computer system to obtain, from one or more health monitoring devices, airway pressure information of the patient and airway flow information of the patient; determine an airway flow limitation index from the airway pressure information of the patient and the airway flow information of the patient; and determine the airway flow limitation value for the patient by comparing the determined airway flow limitation index with an airway flow limitation threshold value. The airway flow limitation value indicates a number of breaths of the patient that are flow limited in a given time period.

Abstract: In certain embodiments, a ventilator may provide interactive guidance for obtaining a subject's expiratory flow limitation results. In some embodiments, the ventilator may cause a progressive color component to be presented, where the progressive color component indicates a progression from one color proximate one side of the progressive color component to another color proximate another side of the progressive color component. The ventilator may cause a forced oscillation to be continuously applied to an airway of the subject for a time period. The ventilator may monitor the subject's degree of expiratory flow limitation based on output signals generated by one or more sensors as the forced oscillation is continuously applied for the time period. The ventilator may cause, based on the monitoring, a movable component's position on the progressive color component to be continuously updated during the time period to indicate the degree of expiratory flow limitation.

Abstract: The present disclosure pertains to a system configured to amplify the pressure and/or flow rate of a pressurized flow of breathable gas by entraining oxygen gas and/or ambient air with an air amplifier and a venturi valve at or near a blending gas source, distally (e.g., remotely) from an interface appliance of a subject interface (e.g., away from the face of the subject) to reduce noise from the system heard by the subject. The system is configured to provide this pressure support and/or ventilation with oxygen therapy. The system is configured to deliver ventilatory and/or pressure support with oxygen therapy while decreasing output requirements of the blending gas source and/or pressure generator.

Abstract: A system for adjusting extrinsic positive end expiratory pressure during an expiratory phase of a ventilator is provided. The system includes a computer system that comprises one or more physical processors programmed with computer program instructions which, when executed cause the computer system to: determine a respiratory reactance from airway flow information of the patient and airway pressure information of the patient, the airway flow information and airway pressure information of the patient being obtained from one or more sensors, and adjust the extrinsic positive end expiratory pressure during the expiratory phase of the ventilator such that the determined respiratory reactance falls within a defined respiratory reactance range.

Abstract: The present disclosure pertains to a system for delivering a humidified flow of concentrated oxygen containing gas to a subject, the system comprising: a subject interface; an oxygen concentrator operatively coupled to the subject interface, the oxygen concentrator configured to provide a flow of concentrated oxygen containing gas to the subject interface via a first conduit; and an aerosol generator operatively coupled to a water supply via a second conduit, the aerosol generator configured to provide a water vapor to the subject interface via the second conduit to humidify the flow of concentrated oxygen containing gas for delivery to the subject.

Abstract: A thrust reverser system for a turbine engine includes a support structure, a transcowl, a door, a lock, and a first elastic element. The transcowl is mounted on the support structure and is translatable between a stowed position, a deployed position, and an over-stow position. The door is pivotally coupled to the support structure and is rotatable between at least a first position, a second position, and a third position. The lock is movable between a locked position, to prevent transcowl translation toward the deployed position, and an unlocked position, to allow transcowl translation toward the deployed position. The lock is only able to move to the unlocked position when the transcowl is in the over-stow position. The first elastic element is disposed within the stowed position aperture and, when engaging both the support structure and the transcowl, supplies a force to the transcowl.

Abstract: An oxygen delivery system provides controlled flow of oxygen-enriched gas to a patient. The system includes one or more sensors configured to measure respiration rate information and heart rate information of the patient. A computer system including one or more physical processors is operatively connected with the sensors. The physical processors are programmed with computer program instructions which, when executed cause the computer system to determine a metabolic oxygen consumption information of the patient from the respiration rate information and the heart rate information from the one or more sensors, and continuously adjust flow, volume and/or pressure of the oxygen-enriched gas delivered from an oxygen source of the oxygen delivery system to the patient based on the determined metabolic oxygen consumption information of the patient.

Abstract: The present ventilator system, for detecting and treating concurrent chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA event(s)) overlap syndrome, comprises a pressure generator for generating a pressurized flow of breathable gas for delivery to an airway of a subject; sensor(s) for generating output signals conveying information related to breathable gas parameters; and processor(s) operatively connected to the sensor(s) and the pressure generator, configured to: detect presence of OSA event(s) and/or expiratory flow limitation (EFL) in the subject based on the output signals.

Abstract: The present invention provides methods, compositions, apparatus, and kits for assessing glycoforms of proteins as a biomarker for disease. A purified recombinant form of lectin is used as a detector molecule to specifically label target sugars expressed in disease states. The high affinity of recombinant lectin allows for automation of assays that would be used in the diagnosis of diseases such as, but not limited to, cancer or liver disease.

Abstract: The present system comprises a pressure generator, an oscillator, sensors, and computer processors. The pressure generator generates a pressurized flow of breathable gas for delivery to the airway of a subject. The oscillator causes high frequency pressure level oscillations in the pressurized flow of breathable gas. The sensors generate output signals conveying information related to one or more parameters of the gas. The computer processors receive a base expiratory pressure level and a base inspiratory pressure level and control the pressure generator and the oscillator to generate the pressurized flow of breathable gas such that during exhalation the pressure level of the pressurized flow of breathable gas oscillates from or about the base expiratory pressure level and during inhalation the pressure level of the pressurized flow of breathable gas oscillates from or about the base inspiratory pressure level.

Abstract: A thrust reverser system comprising a single row vane assembly is provided. The provided thrust reverser system is capable of meeting performance requirements for turbine engines with reduced weight and cost.

Abstract: A thrust reverser system for a turbine engine includes a support structure, a transcowl, a door, a lock, and a first elastic element. The transcowl is mounted on the support structure and is translatable between a stowed position, a deployed position, and an over-stow position. The door is pivotally coupled to the support structure and is rotatable between at least a first position, a second position, and a third position. The lock is movable between a locked position, to prevent transcowl translation toward the deployed position, and an unlocked position, to allow transcowl translation toward the deployed position. The lock is only able to move to the unlocked position when the transcowl is in the over-stow position. The first elastic element is disposed within the stowed position aperture and, when engaging both the support structure and the transcowl, supplies a force to the transcowl.

Abstract: A thrust reverser system for a turbine engine includes a support structure, a transcowl, a door, and an anti-rotation structure. The transcowl is mounted on the support structure and has an inner surface. The transcowl is axially translatable, relative to the support structure, between first and second positions. The door is pivotally coupled to the turbine engine, and has a forward edge and an aft edge. The door is rotatable between stowed and deployed positions when the transcowl translates between the first and second positions, respectively. The anti-rotation structure extends from the transcowl and is disposed adjacent to the aft edge of the door when the transcowl is in the first position and the door is in the stowed position. The anti-rotation structure is configured such that door rotation out of the stowed position only occurs subsequent to or concurrently with translation of the transcowl out of the first position.

Abstract: A system for adjusting extrinsic positive end expiratory pressure during an expiratory phase of a ventilator is provided. The system includes a computer system that comprises one or more physical processors programmed with computer program instructions which, when executed cause the computer system to: determine a respiratory reactance from airway flow information of the patient and airway pressure information of the patient, the airway flow information and airway pressure information of the patient being obtained from one or more sensors, and adjust the extrinsic positive end expiratory pressure during the expiratory phase of the ventilator such that the determined respiratory reactance falls within a defined respiratory reactance range.

Abstract: A thrust reverser system for a turbine engine includes a support structure, a transcowl, a door, a lock, and a first elastic element. The transcowl is mounted on the support structure and is translatable between a stowed position, a deployed position, and an over-stow position. The door is pivotally coupled to the support structure and is rotatable between at least a first position, a second position, and a third position. The lock is movable between a locked position, to prevent transcowl translation toward the deployed position, and an unlocked position, to allow transcowl translation toward the deployed position. The lock is only able to move to the unlocked position when the transcowl is in the over-stow position. The first elastic element is disposed within the stowed position aperture and, when engaging both the support structure and the transcowl, supplies a force to the transcowl.

Abstract: A system and method for reducing idle thrust in a translating cowl reverser system is provided. The provided system and method provide a partial deployment, or thrust reverser system intermediate position for a translating cowl thrust reverser system.

Abstract: In certain embodiments, a ventilator may provide interactive guidance for obtaining a subject's expiratory flow limitation results. In some embodiments, the ventilator may cause a progressive color component to be presented, where the progressive color component indicates a progression from one color proximate one side of the progressive color component to another color proximate another side of the progressive color component. The ventilator may cause a forced oscillation to be continuously applied to an airway of the subject for a time period. The ventilator may monitor the subject's degree of expiratory flow limitation based on output signals generated by one or more sensors as the forced oscillation is continuously applied for the time period. The ventilator may cause, based on the monitoring, a movable component's position on the progressive color component to be continuously updated during the time period to indicate the degree of expiratory flow limitation.

Abstract: An oxygen delivery system provides controlled flow of oxygen-enriched gas to a patient. The system comprises one or more sensors configured to measure respiration rate information and heart rate information of the patient. A computer system comprising one or more physical processors is operatively connected with the sensors. The physical processors are programmed with computer program instructions which, when executed cause the computer system to determine a metabolic oxygen consumption information of the patient from the respiration rate information and the heart rate information from the one or more sensors, and continuously adjust flow, volume and/or pressure of the oxygen-enriched gas delivered from an oxygen source of the oxygen delivery system to the patient based on the determined metabolic oxygen consumption information of the patient.