Patents by Inventor Robert Rona

Robert Rona has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical formulations of spiramycin
    Patent number: 5696095
    Abstract: New formulations of spiramycin suitable for oral administration, particularly for children, comprise spiramycin and potassium acesulfame. These formulations mask the bitterness of spiramycin without adversely affecting the bioavailability or stability of the spiramycin. Preparation by wet granulation followed by dry state mixing is also disclosed.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 9, 1997
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Francois-Xavier Piot, Robert Rona
  • Oral spiramycin formulations and method for preparing same
    Patent number: 5403594
    Abstract: Formulations of spiramycin granules may be conducted by preparing a solution of albumin in the presence of an antifoaming agent, separately preparing a suspension of spiramycin in the presence of an antifoaming agent, granulating and drying a mixture of one or more sugars and water, mixing the albumin solution and spiramycin suspension with heating to coagulate the albumin, evaporating the solvents to obtain spiramycin granules, and mixing the sugar granules and spiramycin granules. Oral spiramycin formulations prepared according to this method are also disclosed.
    Type: Grant
    Filed: July 16, 1993
    Date of Patent: April 4, 1995
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Ana Calvo, Luis A. Del Rio, Manuel Esteban, Robert Rona
  • Process for the preparation of medication in the form of pearls
    Patent number: 5380532
    Abstract: Process for the preparation of pearls based on a pharmaceutical active substance exhibiting an indefinite crystallization point.The said active substance is mixed in molten form with a pharmaceutical excipient promoting the solidification of the active substance, the melt is forced to pass through a nozzle which is subjected to a vibration, the pearls formed are allowed to fall in a tower countercurrentwise to a gas, and the pearls formed are collected in the bottom of the tower.
    Type: Grant
    Filed: July 21, 1992
    Date of Patent: January 10, 1995
    Assignee: Rhone-Poulenc Rorer, S.A.
    Inventors: Michel Deleuil, Pierre Labourt-Ibarre, Robert Rona, Eraclis Statiotis
  • Process for the preparation of medications in the form of pearls
    Patent number: 5188838
    Abstract: Process for the preparation of pearls based on a pharmaceutical active substance exhibiting an indefinite crystallization point. The said active substance is mixed in molten form which a pharmaceutical excipient promoting the solidification of the active substance, the melt is forced to pass through a nozzle which is subjected to a vibration, the pearls formed are allowed to fall in a tower countercurrentwise to a gas, and the pearls formed are collected in the bottom of the tower.
    Type: Grant
    Filed: January 18, 1991
    Date of Patent: February 23, 1993
    Assignee: Rhone-Poulenc Sante
    Inventors: Michel Deleuil, Pierre Labourt-Ibarre, Robert Rona, Eraclis Statiotis