Patents by Inventor Robert Rosa

Robert Rosa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12079115
    Abstract: A system including a development environment data store configured to store development environment data associated with development computer code and a production environment data store configured to store production environment data pertaining to one or more electronic services. The system includes a scenario builder computer is configured to identify one or more scenario parameters relevant to the development computer code, the one or more scenario parameters comprising less than a full set of available scenario parameters and provides the one or more scenario parameters to a scrubber computer.
    Type: Grant
    Filed: March 9, 2022
    Date of Patent: September 3, 2024
    Assignee: United Services Automobile Association (USAA)
    Inventors: Robert Lee Black, Timothy Blair Chalmers, Sumita T. Jonak, David M. Jones, Jr., Gideon Bowie Luck, Ana Rosa Maldonado, Oscar Roberto Tijerina
  • Publication number: 20240238485
    Abstract: Drug-eluting devices and methods for the treatment of tumors of the pancreas, biliary system, gallbladder, liver, small bowel, or colon, are provided. Methods include deploying a drug-eluting device having a film which includes a mixture of a degradable polymer and a chemotherapeutic drug, wherein the film has a thickness from about 2 ?m to about 1000 ?m, into a tissue site and releasing a therapeutically effective amount of the chemotherapeutic drug from the film to treat the tumor, wherein the release of the therapeutically effective amount of the drug from the film is controlled by in vivo degradation of the polymer at the tissue site.
    Type: Application
    Filed: March 29, 2024
    Publication date: July 18, 2024
    Inventors: Laura Indolfi, Elazer R. Edelman, Robert S. Langer, Jeffrey W. Clark, David T. Ting, Cristina Rosa Annamaria Ferrone, Matteo Ligorio
  • Patent number: 10105396
    Abstract: The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties. The invention includes administration of TSG-6, STC-1, or a combination thereof to the ocular as a treatment for an ocular disease, disorder or condition in a mammal.
    Type: Grant
    Filed: June 26, 2017
    Date of Patent: October 23, 2018
    Assignees: The Texas A&M University System, Temple Therapeutics, Inc.
    Inventors: Darwin J. Prockop, Joo Youn Oh, Barry Berkowitz, Gavin W. Roddy, Robert Rosa
  • Publication number: 20180236035
    Abstract: The present invention encompasses methods, compositions, and devices for treating an ocular disease, disorder or condition in a mammal. The invention includes polypeptides that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties, and their application in the treatment of eye disease, particularly diseases of the retina. In particular aspects, the invention includes administration of a therapeutic polypeptide such as a stanniocalcin family member protein for the treatment of an eye disease. Also included are fusion proteins and cells stimulated or modified to express the therapeutic polypeptides as set forth herein.
    Type: Application
    Filed: February 6, 2018
    Publication date: August 23, 2018
    Inventor: Robert Rosa
  • Publication number: 20180015124
    Abstract: The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties. The invention includes administration of TSG-6, STC-1, or a combination thereof to the ocular as a treatment for an ocular disease, disorder or condition in a mammal.
    Type: Application
    Filed: June 26, 2017
    Publication date: January 18, 2018
    Inventors: Darwin J. Prockop, Joo Youn Oh, Barry Berkowitz, Gavin W. Roddy, Robert Rosa
  • Publication number: 20170266261
    Abstract: The present invention encompasses methods, compositions, and devices for treating an ocular disease, disorder or condition in a mammal. The invention includes polypeptides that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties, and their application in the treatment of eye disease, particularly diseases of the retina. In particular aspects, the invention includes administration of a therapeutic polypeptide such as a stanniocalcin family member protein for the treatment of an eye disease. Also included are fusion proteins and cells stimulated or modified to express the therapeutic polypeptides as set forth herein.
    Type: Application
    Filed: November 9, 2016
    Publication date: September 21, 2017
    Inventor: Robert Rosa
  • Patent number: 9730961
    Abstract: The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties. The invention includes administration of TSG-6, STC-1, or a combination thereof to the ocular as a treatment for an ocular disease, disorder or condition in a mammal.
    Type: Grant
    Filed: August 13, 2015
    Date of Patent: August 15, 2017
    Assignees: The Texas A&M University System, Temple Therapeutics, Inc., Scott & White Healthcare
    Inventors: Darwin J. Prockop, Joo Youn Oh, Barry Berkowitz, Gavin W. Roddy, Robert Rosa
  • Patent number: 9498517
    Abstract: The present invention encompasses methods, compositions, and devices for treating an ocular disease, disorder or condition in a mammal. The invention includes polypeptides that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties, and their application in the treatment of eye disease, particularly diseases of the retina. In particular aspects, the invention includes administration of a therapeutic polypeptide such as a stanniocalcin family member protein for the treatment of an eye disease. Also included are fusion proteins and cells stimulated or modified to express the therapeutic polypeptides as set forth herein.
    Type: Grant
    Filed: July 1, 2015
    Date of Patent: November 22, 2016
    Assignees: Scott & White Healthcare, The Texas A&M University System
    Inventors: Robert Rosa, Gavin W. Roddy, Darwin J. Prockop
  • Publication number: 20160058795
    Abstract: The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties. The invention includes administration of TSG-6, STC-1, or a combination thereof to the ocular as a treatment for an ocular disease, disorder or condition in a mammal.
    Type: Application
    Filed: August 13, 2015
    Publication date: March 3, 2016
    Inventors: Darwin J. Prockop, Joo Youn Oh, Barry Berkowitz, Gavin W. Roddy, Robert Rosa
  • Publication number: 20150374791
    Abstract: The present invention encompasses methods, compositions, and devices for treating an ocular disease, disorder or condition in a mammal. The invention includes polypeptides that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties, and their application in the treatment of eye disease, particularly diseases of the retina. In particular aspects, the invention includes administration of a therapeutic polypeptide such as a stanniocalcin family member protein for the treatment of an eye disease. Also included are fusion proteins and cells stimulated or modified to express the therapeutic polypeptides as set forth herein.
    Type: Application
    Filed: July 1, 2015
    Publication date: December 31, 2015
    Inventors: Robert Rosa, Gavin W. Roddy, Darwin J. Prockop
  • Patent number: 9090704
    Abstract: The present invention encompasses methods, compositions, and devices for treating an ocular disease, disorder or condition in a mammal. The invention includes polypeptides that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties, and their application in the treatment of eye disease, particularly diseases of the retina. In particular aspects, the invention includes administration of a therapeutic polypeptide such as a stanniocalcin family member protein for the treatment of an eye disease. Also included are fusion proteins and cells stimulated or modified to express the therapeutic polypeptides as set forth herein.
    Type: Grant
    Filed: May 22, 2014
    Date of Patent: July 28, 2015
    Assignees: Scott & White Healthcare, The Texas A&M University System
    Inventors: Robert Rosa, Gavin W. Roddy, Darwin J. Prockop
  • Patent number: 9062103
    Abstract: The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties. The invention includes administration of TSG-6, STC-1, or a combination thereof to the ocular as a treatment for an ocular disease, disorder or condition in a mammal.
    Type: Grant
    Filed: April 11, 2014
    Date of Patent: June 23, 2015
    Assignees: The Texas A&M University System, Temple Therapeutics, Inc., Scott & White Healthcare
    Inventors: Darwin J. Prockop, Joo Youn Oh, Barry Berkowitz, Gavin W. Roddy, Robert Rosa
  • Publication number: 20140286914
    Abstract: The present invention encompasses methods, compositions, and devices for treating an ocular disease, disorder or condition in a mammal. The invention includes polypeptides that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties, and their application in the treatment of eye disease, particularly diseases of the retina. In particular aspects, the invention includes administration of a therapeutic polypeptide such as a stanniocalcin family member protein for the treatment of an eye disease. Also included are fusion proteins and cells stimulated or modified to express the therapeutic polypeptides as set forth herein.
    Type: Application
    Filed: May 22, 2014
    Publication date: September 25, 2014
    Applicants: Scott & White Healthcare, The Texas A&M University System
    Inventors: Robert Rosa, Gavin W. Roddy, Darwin J. Prockop
  • Patent number: 8785395
    Abstract: The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties. The invention includes administration of TSG-6, STC-1, or a combination thereof to the ocular as a treatment for an ocular disease, disorder or condition in a mammal.
    Type: Grant
    Filed: May 3, 2011
    Date of Patent: July 22, 2014
    Assignees: The Texas A & M University System, Temple Therapeutics, Inc.
    Inventors: Darwin J. Prockop, Joo Youn Oh, Gavin W. Roddy, Robert Rosa, Barry A. Berkowitz
  • Patent number: 8759298
    Abstract: The present invention encompasses methods, compositions, and devices for treating an ocular disease, disorder or condition in a mammal. The invention includes polypeptides that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties, and their application in the treatment of eye disease, particularly diseases of the retina. In particular aspects, the invention includes administration of a therapeutic polypeptide such as a stanniocalcin family member protein for the treatment of an eye disease. Also included are fusion proteins and cells stimulated or modified to express the therapeutic polypeptides as set forth herein.
    Type: Grant
    Filed: July 16, 2012
    Date of Patent: June 24, 2014
    Assignees: Scott & White Healthcare, The Texas A&M University System
    Inventors: Robert Rosa, Gavin W. Roddy, Darwin J. Prockop
  • Publication number: 20130143814
    Abstract: The present invention encompasses methods, compositions, and devices for treating an ocular disease, disorder or condition in a mammal. The invention includes polypeptides that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties, and their application in the treatment of eye disease, particularly diseases of the retina. In particular aspects, the invention includes administration of a therapeutic polypeptide such as a stanniocalcin family member protein for the treatment of an eye disease. Also included are fusion proteins and cells stimulated or modified to express the therapeutic polypeptides as set forth herein.
    Type: Application
    Filed: July 16, 2012
    Publication date: June 6, 2013
    Inventors: Robert Rosa, Gavin W. Roddy, Darwin J. Prockop
  • Publication number: 20130039924
    Abstract: The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties. The invention includes administration of TSG-6, STC-1, or a combination thereof to the ocular as a treatment for an ocular disease, disorder or condition in a mammal.
    Type: Application
    Filed: May 3, 2011
    Publication date: February 14, 2013
    Inventors: Darwin J. Prockop, Yoo Youn Oh, Gavin W. Roddy, Robert Rosa, Barry A. Berkowitz