Abstract: An adapter is provided for use with an infusion set and inserter device used for placement of a subcutaneous infusion set or the like used for delivering a selected medication to a patient. The adapter comprises a first end adapted to be removably coupled to the infusion set and a second end adapted to be removably coupled to an insertion device, particularly the sled fixtured in a track of the insertion tool. The adapter is designed for receiving and supporting an infusion set in a position in the inserter which is used for placement of and insertion of the needle or cannula through the skin of a patient at a selected insertion site. The provided adapter connectors enable the use of a variety of insertion sets having differing configurations with a given inserter having a given configuration.