Abstract: The present invention relates to antibodies that are specific for SARS-CoV-2. The present invention also provides methods of treatment, uses, pharmaceutical compositions and kits comprising the antibodies.

Abstract: The invention relates to antibodies or antigen-binding fragments thereof which specifically bind to CXCR4. The invention also relates to said antibodies for use in therapy, for use in treating cancer, and for use in treating a solid tumor. The invention also relates to pharmaceutical compositions comprising said antibodies, nucleic acids that encode said antibodies, vectors comprising said nucleic acids, and host cells comprising said nucleic acids or vectors.

Abstract: Antibodies that bind ICOS (Inducible T cell Co-Stimulator). Therapeutic use of anti-ICOS antibodies for modulating the ratio between regulatory T cells and effector T cells, to stimulate the immune system of patients, including use in treating cancers. Methods of producing anti-ICOS antibodies, including species cross-reactive antibodies, using transgenic knock-out mice.

Abstract: Antibodies that bind ICOS (Inducible T cell Co-Stimulator). Therapeutic use of anti-ICOS antibodies for modulating the ratio between regulatory T cells and effector T cells, to stimulate the immune system of patients, including use in treating cancers. Methods of producing anti-ICOS antibodies, including species cross-reactive antibodies, using transgenic knock-out mice.

Abstract: A transaction printer includes the MICR encoding of indicia at a precise location called the amount field. In order to accomplish this, an optical sensor is provided in a check processing machine at a point-of-sale to detect the edge of the check and stage it at a known location from the thermal, MICR print head. A clutch mechanism is used to engage the print head with a platen and to engage a read head with the check, so that indicia can be sequentially imprinted and read within the check processing machine in a single, sequential operation that moves the check from a home position to a MICR print position, and subsequently to a MICR read position.