Abstract: A method and apparatus for inserting a watermark into a compiled computer program. A location process specifies an insertion point in the compiled program and a watermark generating process inserts a watermark, based on data to be encoded, into the program at the insertion point. The location process is also utilized to specify the location of watermark data to be decoded.

Abstract: A method for detecting one or more metabolites of a test agent in a tissue including: A) incubating a test agent and an enzyme within a three-dimensional structure comprising a first mold or polymer scaffold, a semi-permeable membrane, and a second mold or polymer scaffold, wherein the semi-permeable membrane is disposed between the first and second molds or polymer scaffolds, and wherein the first mold or polymer scaffold has microchannels that form a fluidic branching network that mimics the forces and transport of natural vasculatures and wherein the second mold or polymer scaffold comprises cells; B) forming an enzyme-substrate complex between the enzyme and the test agent; and C) detecting one or more metabolites of the test agent.

Abstract: The present invention generally relates to a combination of the fields of tissue engineering, drug discovery and drug development. It more specifically provides new methods and materials for testing the efficacy and safety of experimental drugs, defining the metabolic pathways of experimental drugs and characterizing the properties (e.g., side effects, new uses) of existing drugs. Preferably, evaluation is carried out in three-dimensional tissue-engineered systems, wherein drug toxicity, metabolism, interaction and/or efficacy can be determined.

Abstract: A method of determining toxicity of a test agent in a tissue including A) incubating a test agent within a three-dimensional tissue engineered structure comprising a first mold or polymer scaffold, a semi-permeable membrane, and a second mold or polymer scaffold, wherein the semi-permeable membrane is disposed between the first and second molds or polymer scaffolds, and wherein the first mold or polymer scaffold has microchannels comprising vessels that bifurcate, and B) obtaining information from step A) to assess toxicity.

Abstract: A rapid electrochemical flow-through sensor and method for detecting the presence of autoantibodies in a fluid sample such as blood is shown and described. The sensor may take either a single- or multi-plexed form. The sensor comprises a fluid inlet, a reaction region comprising immobilized autoantigens and an electrode assembly, and a fluid outlet.

Abstract: The present invention generally relates to a combination of the fields of tissue engineering, drug discovery and drug development. It more specifically provides new methods and materials for testing the efficacy and safety of experimental drugs, defining the metabolic pathways of experimental drugs and characterizing the properties (e.g., side effects, new uses) of existing drugs. Preferably, evaluation is carried out in three-dimensional tissue-engineered systems, wherein drug toxicity, metabolism, interaction and/or efficacy can be determined.

Abstract: A system and method for information distribution and retrieval. A preferred embodiment comprises downloading information, such as data, an application, and the like, from a server to a client. The information may be distributed to other clients without the need of a network connection to the server. Furthermore, modifications to the information made by the client may be distributed to other clients and the server. In another embodiment, the present invention downloads segments on an as needed basis. The segments may be reusable to provide further benefits. A relatively small application utilizes the reusable segments and an activity graph to perform specific functions.

Abstract: On the seat of a motorcycle, a strap, typically located between the front and rear seats of the motorcycle seat, may be grasped by the rear seat passenger. A cover for the entire seat is stowed in a pocket in the strap. The pocket is openable to permit deployment of the cover over the seat and the cover may be re-stowed within the pocket in the strap. Closure elements close the pocket of the strap.

Abstract: A sock having a pocket supported inside its leg portion. A first vertical slit opening in the sock provides access to the pocket within the sock and that opening is closed by a zipper. The pocket has a corresponding slit opening in one wall and the margins of the slit opening in the pocket are stitched along the margins of the two tracks of the zipper closure at the opposite sides of the slit opening in the sock. That is the only securement of the pocket to the sock, avoiding additional stitching or fastening of the pocket to the leg portion of the sock. The pocket is large enough and wide enough to hold needed objects.